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Entry version 45 (05 Jun 2019)
Sequence version 1 (09 Jan 2013)
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Protein
Submitted name:

KIF20B isoform 3

Gene

KIF20B

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi152 – 159ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
KIF20B isoform 3Imported
Submitted name:
Kinesin family member 20BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KIF20BImported
ORF Names:CK820_G0004348Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan troglodytes (Chimpanzee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini58 – 479Kinesin motorInterPro annotationAdd BLAST422

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni790 – 827DisorderedSequence analysisAdd BLAST38
Regioni1209 – 1237DisorderedSequence analysisAdd BLAST29
Regioni1638 – 1657DisorderedSequence analysisAdd BLAST20
Regioni1722 – 1743DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili570 – 600Sequence analysisAdd BLAST31
Coiled coili677 – 753Sequence analysisAdd BLAST77
Coiled coili844 – 885Sequence analysisAdd BLAST42
Coiled coili907 – 934Sequence analysisAdd BLAST28
Coiled coili1031 – 1103Sequence analysisAdd BLAST73
Coiled coili1142 – 1176Sequence analysisAdd BLAST35
Coiled coili1357 – 1391Sequence analysisAdd BLAST35
Coiled coili1396 – 1423Sequence analysisAdd BLAST28
Coiled coili1463 – 1483Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi790 – 805PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1209 – 1227PolyampholyteSequence analysisAdd BLAST19

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0247 Eukaryota
COG5059 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.850.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028828 KIF20B
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR24115 PTHR24115, 1 hit
PTHR24115:SF534 PTHR24115:SF534, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00225 Kinesin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00380 KINESINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00129 KISc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K7CXE0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESNFNQEGV PRPSYVFSAD PIARPSEINF DGIKLDLSHE FSLVAPNTEA
60 70 80 90 100
NSFESKDYLQ VCLRIRPFTQ SEKELESEGC VHILDSQTVV LKEPQCILGR
110 120 130 140 150
LSEKSSGQMA QKFSFSKVFG PATTQKEFFQ GCIMQPVKDL LEGQSRLIFT
160 170 180 190 200
YGLTNSGKTY TFQGTEENIG ILPRTLNVLF DSLQDRLYTK MNLKPHRSRE
210 220 230 240 250
YLRLSSEQEK EEIASKSALL RQIKEVTVRN DSDDTLYGSL TNSLNISEFE
260 270 280 290 300
ESIKDYEQAN LNMANSIKFS VWVSFFEIYN EYIYDLFVPV SSKFQKRKML
310 320 330 340 350
RLSQDVKGYS FIKDLQWIQV SDSKEAYRLL KLGIKHQSVA FTKLNNASSR
360 370 380 390 400
SHSIFTVKIL QIEDSEMSRV IRVSELSLCD LAGSERTMKT QNEGERLRET
410 420 430 440 450
GNINTSLLTL GKCINVLKNS EKSKFQQHVP FRESKLTHYF QSFFNGKGKI
460 470 480 490 500
CMIVNISQCY LAYDETLNVL KFSAIAQKVC VPDTLNSSQE KLFGPVKSSQ
510 520 530 540 550
DVSLDSNSNS KILNVKRATI SWENSLEDLM EDEDLVEELE NTEETQNVET
560 570 580 590 600
KLLDEDLDKT LEENKAFISH EEKRKLLDLI EDLKKKLINE KKEKLTLEFK
610 620 630 640 650
IREEVTQEFT QYWAQREADF KETLLQEREI LEENAERRLA IFKDLVGKCD
660 670 680 690 700
TREEPAKDIC ATKVETEEAT ACLELKFNQI KAELAKTKGE LIKTKEELKK
710 720 730 740 750
REDESDSLIQ ELETSNKKII TQNQRIKELI NIIDQKEDTI NEFQNLKSHM
760 770 780 790 800
ENTFKCNDKA DTSSLIINNK LICNETVEVP KDSKTKICSE RKRVNENELQ
810 820 830 840 850
QDEPPAKKGS IHVSSAITED QKKSEEVRPN IAEIEDIRVL QENNEGLRAF
860 870 880 890 900
LLTIENELKN EKEEKAELNK QIVRFQQELS LSEKKNLTLS KEVQQIQSNY
910 920 930 940 950
DIAIAELHVQ KSKNQEQEEK IMKLSNEIET ATRSITNNVS QIKLMHTKID
960 970 980 990 1000
ELRTLDSVSQ ISNIDLLNLR DLSNGSEEDN LPNTQLHLLG NDYLVSKQVK
1010 1020 1030 1040 1050
EYRIQEPNRE NSFHSSIEAI WEECKEIVKA SSKKSHQIEE LEQQIEKLQA
1060 1070 1080 1090 1100
EVKGYKDENN RLKVKEKEHK NQDDLLKEKE TLIQQLKEEL QEKNVTLDVQ
1110 1120 1130 1140 1150
IQHVVEGKRA LSELTQGVTC YKAKIKELET ILETQKVERS HSAKLEQDIL
1160 1170 1180 1190 1200
EKESIILKLE RNLKEFQEHL QDSVKNTKDL SVKELKLKEE ITQLTNNLQD
1210 1220 1230 1240 1250
MKHLLQLKEE EEETNRQETE KLKEELSASS ARTQNLKADL QRKEEDYADL
1260 1270 1280 1290 1300
KEKLTDAKKQ IEQVQKEVSV MRDEDKLLRI KINELEKKKN QCSQELDMKQ
1310 1320 1330 1340 1350
RTIQQLKEQL NNQKVEEAIQ QYERACKDLN VKEKIIEDMR MTLEEQEQTQ
1360 1370 1380 1390 1400
VEQDQVLEAK LEEVERLATE LEKWKEKCND LETKNNQRSN KEHENNTDVL
1410 1420 1430 1440 1450
GKLTNLQDEL QESEQKYNAD RKKWLEEKMM LITQAKEAEN IRNKEMKKYA
1460 1470 1480 1490 1500
EDRERFFKQQ NEMEILTAQL TEKDSDLQKW REERDQLVAA LEIQLKALIS
1510 1520 1530 1540 1550
SNVQKDNEIE QLKRIISETS KIETQIMDIK PKRISSADPD KLQTEPLSTS
1560 1570 1580 1590 1600
FEISRNKVED GSVVLDSCEV STENDQSTRF PKPELEIQFT PLQPNKMAVK
1610 1620 1630 1640 1650
HPGCTTPVTV KIPKARKRKS NEMEEDLVKC ENKKNATPRT NVKFPISDDR
1660 1670 1680 1690 1700
NSSVKKEQKV AIRPSSKKTY SLRSQASIIG VNLATKKKEG TLQKFGDFLQ
1710 1720 1730 1740 1750
HSPSILQSKA KKIIETMSSS KLSNVEASKE NVSQPKRAKR KLYTSEISSP
1760 1770 1780
IDISGQVILM DQKMKESDHQ IIKRRLRTKT AK
Length:1,782
Mass (Da):206,480
Last modified:January 9, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE96B3BAE3AD1D27C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GABC01005966 mRNA Translation: JAA05372.1
GABD01001516 mRNA Translation: JAA31584.1
NBAG03000216 Genomic DNA Translation: PNI82354.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GABC01005966 mRNA Translation: JAA05372.1
GABD01001516 mRNA Translation: JAA31584.1
NBAG03000216 Genomic DNA Translation: PNI82354.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0247 Eukaryota
COG5059 LUCA

Family and domain databases

Gene3Di3.40.850.10, 2 hits
InterProiView protein in InterPro
IPR028828 KIF20B
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 1 hit
PTHR24115:SF534 PTHR24115:SF534, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK7CXE0_PANTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K7CXE0
Secondary accession number(s): A0A2J8PEA4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: June 5, 2019
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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