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Protein
Submitted name:

TEX2 isoform 3

Gene

TEX2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transportSAAS annotation, Transport
LigandLipid-bindingSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
TEX2 isoform 3Imported
Submitted name:
Testis expressed 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TEX2Imported
ORF Names:CK820_G0011590Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan troglodytes (Chimpanzee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002277 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:9704 TEX2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei471 – 489HelicalSequence analysisAdd BLAST19
Transmembranei496 – 516HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSPTRG00000009537 Expressed in 6 organ(s), highest expression level in testis

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9598.ENSPTRP00000016202

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini823 – 1108SMP-LTDInterPro annotationAdd BLAST286

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2238 Eukaryota
ENOG410Z3SZ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000463

Identification of Orthologs from Complete Genome Data

More...
OMAi
HWNTRSL

Database of Orthologous Groups

More...
OrthoDBi
EOG091G01R4

TreeFam database of animal gene trees

More...
TreeFami
TF314900

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031468 SMP_LBD

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51847 SMP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K7CET3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSLYGRHAE KTTDMPKPSA PKVHVQRSVS RDTIAIHFSA SGEEEEEEEE
60 70 80 90 100
EFREYFEEGL DDQSIVTGLE AKEDLYLEPQ VGHDPAGPAA SPVLADGLSV
110 120 130 140 150
SQAPAILPVS KNTVKLLESP VPAAQVLSTV PLAVSPGSSS SGPLASSPSV
160 170 180 190 200
SSLSEQKTSS SSPLSSPSKS PILSSSASTS TLSSAKPFMS LVKSLSTEVE
210 220 230 240 250
PKESPHPARH RHLMKTLVKS LSTDTSRQES DTVSYKPPDS KLNLHLFKQF
260 270 280 290 300
TQPRNTGGDS KTAPSSPLTS PSDTRSFFKV PEMEAKIEDT KRRLSEVIYE
310 320 330 340 350
PFQLLSKIIG EESGSHRPKA LSSSASELSN LSSLNGHLES NNNYSIKEEE
360 370 380 390 400
CDSEGDGYGS DSNIPRSDHP KSTDEPTREI ELKSSQGSSL KDLGLKTSSL
410 420 430 440 450
VLEKCSLSAL VSKEDEEFCE LYTEDFDLET EGESKVDKLS DIPLKPEVLA
460 470 480 490 500
EDGVVLDSED EVDSAVQHPE LPVKTLGFFT MCVYVYLILP LPHYVSGLFL
510 520 530 540 550
GIGLGFMTAV CVIWFFTPPS AHKYHKLHKN LRHWNTRSLD IKEPEILKGW
560 570 580 590 600
MNEIYNYDPE TYHATLTHSV FVRLEGGTLR LSKPNKNISR RASYNEPKPE
610 620 630 640 650
VTYISQKIYD LSDSKIYLVP KTLARKRIWN KKYPICIELG QQDDFMSKAQ
660 670 680 690 700
TDKETSEEKP PAEGSEDPKK PPRPQEGTRS SQRDQILYLF GRTGREKEEW
710 720 730 740 750
FRRFILASKL KSEIKKSSGV SGGKPAPVFL APGLLPAHSR HNSPSGHLTH
760 770 780 790 800
SRSSSKGSVE EIMSQPKQKE LAGSVRQKML LDYSVYMGRC VPQESRSPQR
810 820 830 840 850
SPLQSAESSP TAGKKLPEVP PSEEEEQEAW VNALLGRIFW DFLGEKYWSD
860 870 880 890 900
LVSKKIQMKL SKIKLPYFMN ELTLTELDMG VAVPKILQAF KPYVDHQGLW
910 920 930 940 950
IDLEMSYNGS FLMTLETKMN LTKLGKEPLV EALKVGEIGK EGCRPRAFCL
960 970 980 990 1000
ADSDEESSSA GSSEEDDAPE PSGGDKQLLP GAEGYVGGHR TSKIMRFVDK
1010 1020 1030 1040 1050
ITKSKYFQKA TETEFIKKKI EEVSNTPLLL TVEVQECRGT LAVNIPPPPT
1060 1070 1080 1090 1100
DRLWYGFRKP PHVELKARPK LGEREVTLVH VTDWIEKKLE QEFQKVFVMP
1110 1120 1130
NMDDVYITIM HSAMDPRSTS CLLKDSPVEA ADQP
Length:1,134
Mass (Da):126,049
Last modified:January 9, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i559E0C75FA2FCDD9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AACZ04070141 Genomic DNA No translation available.
GABC01004880 mRNA Translation: JAA06458.1
GABD01008281 mRNA Translation: JAA24819.1
NBAG03000001 Genomic DNA Translation: PNJ01237.1

NCBI Reference Sequences

More...
RefSeqi
XP_016788243.1, XM_016932754.1
XP_511583.3, XM_511583.6

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPTRT00000017493; ENSPTRP00000016202; ENSPTRG00000009537

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
454767

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04070141 Genomic DNA No translation available.
GABC01004880 mRNA Translation: JAA06458.1
GABD01008281 mRNA Translation: JAA24819.1
NBAG03000001 Genomic DNA Translation: PNJ01237.1
RefSeqiXP_016788243.1, XM_016932754.1
XP_511583.3, XM_511583.6

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000016202

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000017493; ENSPTRP00000016202; ENSPTRG00000009537
GeneIDi454767

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55852
VGNCiVGNC:9704 TEX2

Phylogenomic databases

eggNOGiKOG2238 Eukaryota
ENOG410Z3SZ LUCA
GeneTreeiENSGT00390000000463
OMAiHWNTRSL
OrthoDBiEOG091G01R4
TreeFamiTF314900

Gene expression databases

BgeeiENSPTRG00000009537 Expressed in 6 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR031468 SMP_LBD
PROSITEiView protein in PROSITE
PS51847 SMP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK7CET3_PANTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K7CET3
Secondary accession number(s): A0A2J8QY97, H2QDP1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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