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Protein
Submitted name:

NR4A1 isoform 1

Gene

NR4A1

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi264 – 339Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
NR4A1 isoform 1Imported
Submitted name:
NR4A1 isoform 2Imported
Submitted name:
NR4A1 isoform 4Imported
Submitted name:
Nuclear receptor subfamily 4, group A, member 1Imported
Gene namesi
Name:NR4A1Imported
ORF Names:CK820_G0039616Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000039485

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini264 – 339Nuclear receptorInterPro annotationAdd BLAST76
Domaini360 – 595NR LBDInterPro annotationAdd BLAST236

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4217 Eukaryota
ENOG410YWNC LUCA
KOiK04465
OrthoDBiEOG091G0GUM
TreeFamiTF315430

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR003071 Nuc_orp_HMR_rcpt
IPR003070 Nuc_orph_rcpt
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01285 HMRNUCRECPTR
PR01284 NUCLEARECPTR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

K7BQ21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPCIQAQYGT PAPSPGPHDH LASDPLTPEF IKPTMDLASP EAAPTAPTAL
60 70 80 90 100
PSFSTFMDGY TGEFDTFLYQ LPGTVQPCSS ASSSASSTSS SSATSPASAS
110 120 130 140 150
FKFEDFQVYG CYPGPLSGPV DEALSSSGSD YYGSPCSAPS PSTPSFQPPQ
160 170 180 190 200
LSPWDGSFGH FSPSQTYEGL RAWTEQLPKA SGPPQPPAFF SFSPPTGPSP
210 220 230 240 250
SLAQSPLKLF PSQATHQLGE GESYSMPTAF PGLAPTSPHL EGSGILDAPV
260 270 280 290 300
TSTKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK
310 320 330 340 350
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP
360 370 380 390 400
SKPKQPPDAS PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPRFGKEDA
410 420 430 440 450
EDVQQFYDLL SGSLEVIRKW AEKIPGFAEL SPADQDLLLE SAFLELFILR
460 470 480 490 500
LAYRSKPGEG KLIFCSGLVL HRLQCARGFG DWIDSILAFS RSLHSLLVDV
510 520 530 540 550
PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVA AVAGEPQPAS
560 570 580 590
CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF
Length:598
Mass (Da):64,535
Last modified:February 28, 2018 - v1
Checksum:i54253029CB2B4F55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GABF01005956 mRNA Translation: JAA16189.1
GABE01005505 mRNA Translation: JAA39234.1
NBAG03000375 Genomic DNA Translation: PNI33081.1
NBAG03000375 Genomic DNA Translation: PNI33082.1
NBAG03000375 Genomic DNA Translation: PNI33084.1
RefSeqiXP_003313737.1, XM_003313689.3
XP_003313738.1, XM_003313690.3
XP_003952237.1, XM_003952188.3

Genome annotation databases

GeneIDi451913
KEGGiptr:451913

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GABF01005956 mRNA Translation: JAA16189.1
GABE01005505 mRNA Translation: JAA39234.1
NBAG03000375 Genomic DNA Translation: PNI33081.1
NBAG03000375 Genomic DNA Translation: PNI33082.1
NBAG03000375 Genomic DNA Translation: PNI33084.1
RefSeqiXP_003313737.1, XM_003313689.3
XP_003313738.1, XM_003313690.3
XP_003952237.1, XM_003952188.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000039485

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi451913
KEGGiptr:451913

Organism-specific databases

CTDi3164

Phylogenomic databases

eggNOGiKOG4217 Eukaryota
ENOG410YWNC LUCA
KOiK04465
OrthoDBiEOG091G0GUM
TreeFamiTF315430

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR003071 Nuc_orp_HMR_rcpt
IPR003070 Nuc_orph_rcpt
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01285 HMRNUCRECPTR
PR01284 NUCLEARECPTR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7BQ21_PANTR
AccessioniPrimary (citable) accession number: K7BQ21
Secondary accession number(s): A0A2J8KDI8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: September 12, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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