Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 25 (05 Jun 2019)
Sequence version 1 (09 Jan 2013)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

BCL6 corepressor

Gene

BCOR

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
BCL6 corepressorImported
Submitted name:
BCOR isoform 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BCORImported
ORF Names:CK820_G0054238Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan troglodytes (Chimpanzee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1410 – 1515ANK_REP_REGIONInterPro annotationAdd BLAST106
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1444 – 1476ANKPROSITE-ProRule annotationAdd BLAST33
Repeati1477 – 1509ANKPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni309 – 345DisorderedSequence analysisAdd BLAST37
Regioni388 – 438DisorderedSequence analysisAdd BLAST51
Regioni557 – 641DisorderedSequence analysisAdd BLAST85
Regioni737 – 760DisorderedSequence analysisAdd BLAST24
Regioni773 – 794DisorderedSequence analysisAdd BLAST22
Regioni815 – 844DisorderedSequence analysisAdd BLAST30
Regioni1052 – 1276DisorderedSequence analysisAdd BLAST225
Regioni1378 – 1399DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili991 – 1011Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1052 – 1087PolyampholyteSequence analysisAdd BLAST36
Compositional biasi1110 – 1144PolyampholyteSequence analysisAdd BLAST35
Compositional biasi1145 – 1159BasicSequence analysisAdd BLAST15
Compositional biasi1182 – 1197PolarSequence analysisAdd BLAST16
Compositional biasi1202 – 1223PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1224 – 1254PolarSequence analysisAdd BLAST31
Compositional biasi1378 – 1396PolarSequence analysisAdd BLAST19

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHDH Eukaryota
ENOG410YT00 LUCA

Database of Orthologous Groups

More...
OrthoDBi
85469at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit
3.10.260.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR031628 BCOR
IPR032365 PUFD
IPR038227 PUFD_som_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit
PF15808 BCOR, 1 hit
PF16553 PUFD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K7BCB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSATPLYGN VHSWMNSERV RMCGASEDRK ILVNDGDASK ARLELREENP
60 70 80 90 100
LNHNVVDAST AHRIDGLAAL SMDRTGLIRE GLRVPGNIVY SSLCGLGSEK
110 120 130 140 150
GREAATSTLG GLGFSSERNP EMQFKPNTPE TVEASAVSGK PPNGFSAMYK
160 170 180 190 200
TPPGIQKSAV ATAEALGLDR PASDKQSPLN INGASYLRLP WVNPYMEGAT
210 220 230 240 250
PAIYPFLDSP NKYSLNMYKA LLPQQSYSLA QPLYSPVCTN GERFLYLPPP
260 270 280 290 300
HYVGPHIPSS LASPMRLSTP SASPAIPPLV HCADKSLPWK MGVSPGNPVD
310 320 330 340 350
SHAYPHIQNS KQPRVPSAKA VTSGLPGDTA LLLPPSPRPS PRVHLPTQPA
360 370 380 390 400
ADTYSEFHKH YARISTSPSV ALSKPYMTVS SEFPAARLSN GKYPKAPEGG
410 420 430 440 450
EGAQPVPGHA RKTAVQDRKD GSSPPLLEKQ TVTKDVTDKP LDLSSKVVDV
460 470 480 490 500
DASKADHMKK MAPTVLVHSR AGSGLVLSGS EIPKETLSPP GNGCAIYRSE
510 520 530 540 550
IISTAPSSWV VPGPSPNEEN NGKSMSLKNK ALDWAIPQQR SSSCPRMGGT
560 570 580 590 600
DAVITNVSGS VSSAGRPASA SPAPNANADG TKTSRSSVET TPSVIQHVGQ
610 620 630 640 650
PPATPAKHSS STSSKGAKAS NPEPSFKANE NGLPPSSIFL SPNDAFRSPP
660 670 680 690 700
IPYPRSYLPY PAPEGIAVSP LSLHGKGPVY PHPVLLPNGS LFPGHLAPKP
710 720 730 740 750
GLPYGLPTGR PEFVTYQDAL GLGMVHPMLI PHTPIEITKE EKPERRSRSH
760 770 780 790 800
ERARYEDPTL RNRFSEILET SSTKLHPDVP TDKNLKPNPN WNQGKTVVKS
810 820 830 840 850
DKLVYVDLLR EEPDAKTDTN VSKPSFAAES VGQSAEPPKP SVEPALQQHR
860 870 880 890 900
DFIALREELG RISDFHETYT FKQPVFTVSK DSVLAGTNKE NLGLPVSTPF
910 920 930 940 950
LEPPLGSDGP AVTFGKTQED PKPFCVGSAP PSVDVTPTYT KDGADEAESN
960 970 980 990 1000
DGKVLKPKPS KLAKRIANSA GYVGDRFKCV TTELYADSSQ LSREQRALQR
1010 1020 1030 1040 1050
AMMRFSELEM KEREGGHPAT KDSEMCKFSP ADWERLKGNQ DKKPKSVALE
1060 1070 1080 1090 1100
EAIAEQNESE RCEYSVGNKH HDPFEAPEDK DLPVEKYFVE RQPVSEPPAD
1110 1120 1130 1140 1150
QVASDMPHSP TLRVDRKRKV SGDSSHTETT AEEVPEDPLL KAKRRRVSKG
1160 1170 1180 1190 1200
LHPKKQRHLL HLRERWEQQV SAADGKPGRQ SRKEVTQATQ PEAIPQGTNI
1210 1220 1230 1240 1250
TEEKPGRKRA EAKGNRSWSE ESLKPSDNEQ GLPVFSGSPP MKSLSSTSAG
1260 1270 1280 1290 1300
GKKQAQPSCA PASRPPAKQQ KIKENQKTDV LCADEEEDCQ AASLLQKYTD
1310 1320 1330 1340 1350
NSEKPSGKRL CKTKHLIPQE SRRGLPLTGE YYVENADGKV TVRRFRKRPE
1360 1370 1380 1390 1400
PSSDYDLSPA KQEPKPFDRL QQLLPASQST QLPCSSSPQE TTQSRPMPPE
1410 1420 1430 1440 1450
ARRLIVNKNA GETLLQRAAR LGYEEVVLYC LENKICDVNH RDNAGYCALH
1460 1470 1480 1490 1500
EACARGWLNI VRHLLEYGAD VNCSAQDGTR PLHDAVENDH LEIVRLLLSY
1510 1520 1530 1540 1550
GADPTLATYS GRTIMKMTHS ELMEKFLTDY LNDLQGRNDD DASGAWDFYG
1560 1570 1580 1590 1600
SSVCEPDDES GYDVLANPPG PEDQDDDDDA YSDVFEFEFS ETPLLPCYNI
1610 1620 1630 1640 1650
QVSVAQGPRN WLLLSDVLKK LKMSSRIFRC NFPNVEIVTI AEAEFYRQVS
1660 1670 1680 1690 1700
ASLLFSCSKD LEAFNPESKE LLDLVEFTNE IQTLLGSSVE WLHPSDLASD

NYW
Length:1,703
Mass (Da):186,160
Last modified:January 9, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA704ABE1B03A93F9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GABC01001698 mRNA Translation: JAA09640.1
NBAG03000645 Genomic DNA Translation: PNI12599.1

NCBI Reference Sequences

More...
RefSeqi
XP_016798926.1, XM_016943437.1
XP_016803024.1, XM_016947535.1
XP_016803025.1, XM_016947536.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
465574

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GABC01001698 mRNA Translation: JAA09640.1
NBAG03000645 Genomic DNA Translation: PNI12599.1
RefSeqiXP_016798926.1, XM_016943437.1
XP_016803024.1, XM_016947535.1
XP_016803025.1, XM_016947536.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi465574

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54880

Phylogenomic databases

eggNOGiENOG410IHDH Eukaryota
ENOG410YT00 LUCA
OrthoDBi85469at2759

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
3.10.260.40, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR031628 BCOR
IPR032365 PUFD
IPR038227 PUFD_som_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF15808 BCOR, 1 hit
PF16553 PUFD, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK7BCB5_PANTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K7BCB5
Secondary accession number(s): A0A2J8IQ16
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: June 5, 2019
This is version 25 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again