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Entry version 56 (25 May 2022)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

RCaMP

Gene
N/A
Organism
Entacmaea quadricolor (Bubble-tip anemone) (Parasicyonis actinostoloides)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi304Calcium 1Combined sources1
Metal bindingi306Calcium 1Combined sources1
Metal bindingi306Calcium 2Combined sources1
Metal bindingi308Calcium 1Combined sources1
Metal bindingi308Calcium 2Combined sources1
Metal bindingi310Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi310Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi315Calcium 1Combined sources1
Metal bindingi315Calcium 2Combined sources1
Metal bindingi340Calcium 3Combined sources1
Metal bindingi342Calcium 3Combined sources1
Metal bindingi342Calcium 4Combined sources1
Metal bindingi344Calcium 3Combined sources1
Metal bindingi344Calcium 4Combined sources1
Metal bindingi346Calcium 3; via carbonyl oxygenCombined sources1
Metal bindingi346Calcium 4; via carbonyl oxygenCombined sources1
Metal bindingi351Calcium 3Combined sources1
Metal bindingi351Calcium 4Combined sources1
Metal bindingi377Calcium 5Combined sources1
Metal bindingi377Calcium 6Combined sources1
Metal bindingi377Calcium 7Combined sources1
Metal bindingi379Calcium 5Combined sources1
Metal bindingi379Calcium 6Combined sources1
Metal bindingi379Calcium 7Combined sources1
Metal bindingi381Calcium 5Combined sources1
Metal bindingi381Calcium 6Combined sources1
Metal bindingi381Calcium 7Combined sources1
Metal bindingi383Calcium 5; via carbonyl oxygenCombined sources1
Metal bindingi383Calcium 6; via carbonyl oxygenCombined sources1
Metal bindingi383Calcium 7; via carbonyl oxygenCombined sources1
Metal bindingi388Calcium 5Combined sources1
Metal bindingi388Calcium 6Combined sources1
Metal bindingi388Calcium 7Combined sources1
Metal bindingi413Calcium 8Combined sources1
Metal bindingi413Calcium 9Combined sources1
Metal bindingi415Calcium 8Combined sources1
Metal bindingi415Calcium 9Combined sources1
Metal bindingi417Calcium 8Combined sources1
Metal bindingi417Calcium 9Combined sources1
Metal bindingi419Calcium 8; via carbonyl oxygenCombined sources1
Metal bindingi419Calcium 9; via carbonyl oxygenCombined sources1
Metal bindingi424Calcium 8Combined sources1
Metal bindingi424Calcium 9Combined sources1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionPhotoproteinARBA annotation
Biological processLuminescence
LigandCalciumCombined sources, ChromophoreARBA annotation, Metal-bindingCombined sources

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.82.1.7, the calmodulin calcium binding protein (calmodulin) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RCaMPImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEntacmaea quadricolor (Bubble-tip anemone) (Parasicyonis actinostoloides)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6118 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaActiniidaeEntacmaea

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
K4DIE3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini291 – 326EF-handInterPro annotationAdd BLAST36
Domaini327 – 362EF-handInterPro annotationAdd BLAST36
Domaini364 – 399EF-handInterPro annotationAdd BLAST36
Domaini400 – 432EF-handInterPro annotationAdd BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GFP family.ARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00051, EFh, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.155.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR009017, GFP
IPR011584, GFP-related
IPR000786, Green_fluorescent_prot

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13499, EF-hand_7, 2 hits
PF01353, GFP, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01229, GFLUORESCENT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00054, EFh, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473, SSF47473, 1 hit
SSF54511, SSF54511, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018, EF_HAND_1, 4 hits
PS50222, EF_HAND_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K4DIE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASMTGGQQM GRDLYDDDDK DLATMVDSSR RKWNKTGHAV RAIGRLSSAI
60 70 80 90 100
NTEMMYPADG GLRGYTHMAL KVDGGGHLSC SFVTTYRSKK TVGNIKMPGI
110 120 130 140 150
HYVSHRLERL EESDNEMFVV QREHAVAKFV GLGGGGGTGG SMNSLIKENM
160 170 180 190 200
RMKVVLEGSV NGHQFKCTGE GEGNPYMGTQ TMRIKVIEGG PLPFAFDILA
210 220 230 240 250
TSFMYGSRTF IKYPKGIPDF FKQSFPEGFT WERVTRYEDG GVITVMQDTS
260 270 280 290 300
LEDGCLVYHA QVRGVNFPSN GAVMQKKTKG WEPTRDQLTE EQIAEFKEAF
310 320 330 340 350
SLFDKDGDGT ITTKELGTVM RSLGQNPTEA ELQDMINEVD ADGDGTIDFP
360 370 380 390 400
EFLIMMARKM KDTDSEEEIR EAFRVFDKDG NGYISAAELR HVMTNLGEKL
410 420 430
TDEEVDEMIR EADIDGDGQV NYEEFVQMMT AK
Length:432
Mass (Da):48,114
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i733D9A319AE45613
GO

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3U0KX-ray2.10A1-432[»]
4IK1X-ray2.00A1-48[»]
A51-147[»]
A279-283[»]
A306-338[»]
A342-354[»]
A361-362[»]
A368-432[»]
4IK3X-ray2.01A1-48[»]
A51-147[»]
A279-283[»]
A306-338[»]
A342-354[»]
A361-362[»]
A368-432[»]
4IK4X-ray2.01A1-48[»]
A51-147[»]
A279-283[»]
A306-338[»]
A342-354[»]
A361-362[»]
A368-432[»]
4IK5X-ray2.50A25-48[»]
A51-147[»]
A279-283[»]
A306-338[»]
A342-354[»]
A361-362[»]
A368-432[»]
4IK8X-ray1.55A1-48[»]
A51-147[»]
A279-283[»]
A306-338[»]
A342-354[»]
A361-362[»]
A368-432[»]
4IK9X-ray1.80A1-48[»]
A51-147[»]
A279-283[»]
A306-338[»]
A342-354[»]
A361-362[»]
A368-432[»]
6ZSMX-ray1.95A51-147[»]
A218-218[»]
A225-269[»]
A295-300[»]
A312-336[»]
A348-362[»]
A369-432[»]
6ZSNX-ray2.60A51-147[»]
A218-218[»]
A225-269[»]
A295-300[»]
A312-336[»]
A348-362[»]
A369-432[»]
SMRiK4DIE3
ModBaseiSearch...
PDBe-KBiSearch...

Protein family/group databases

TCDBi8.A.82.1.7, the calmodulin calcium binding protein (calmodulin) family

Family and domain databases

CDDicd00051, EFh, 2 hits
Gene3Di2.40.155.10, 1 hit
InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR009017, GFP
IPR011584, GFP-related
IPR000786, Green_fluorescent_prot
PfamiView protein in Pfam
PF13499, EF-hand_7, 2 hits
PF01353, GFP, 2 hits
PRINTSiPR01229, GFLUORESCENT
SMARTiView protein in SMART
SM00054, EFh, 4 hits
SUPFAMiSSF47473, SSF47473, 1 hit
SSF54511, SSF54511, 2 hits
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 4 hits
PS50222, EF_HAND_2, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK4DIE3_ENTQU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K4DIE3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: May 25, 2022
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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