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Entry version 44 (16 Oct 2019)
Sequence version 1 (28 Nov 2012)
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Protein

Receptor-like serine/threonine-protein kinase

Gene
N/A
Organism
Setaria italica (Foxtail millet) (Panicum italicum)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Receptor-like serine/threonine-protein kinaseUniRule annotation (EC:2.7.11.1UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSetaria italica (Foxtail millet) (Panicum italicum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4555 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaePanicodaePaniceaeCenchrinaeSetaria

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0515 LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
TKANTHR

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00028 B_lectin, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.90.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001480 Bulb-type_lectin_dom
IPR036426 Bulb-type_lectin_dom_sf
IPR000742 EGF-like_dom
IPR011009 Kinase-like_dom_sf
IPR003609 Pan_app
IPR000719 Prot_kinase_dom
IPR000858 S_locus_glycoprot_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
IPR024171 SRK-like_kinase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01453 B_lectin, 1 hit
PF08276 PAN_2, 1 hit
PF07714 Pkinase_Tyr, 1 hit
PF00954 S_locus_glycop, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000641 SRK, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00108 B_lectin, 1 hit
SM00473 PAN_AP, 1 hit
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51110 SSF51110, 1 hit
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50927 BULB_LECTIN, 1 hit
PS50026 EGF_3, 1 hit
PS50948 PAN, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K4A357-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAWSAIRYAA TVLLLLLLLV QPCASDDRLV PGKPLFPSAT IVSDGGSIAL
60 70 80 90 100
GFFSLTNSTP AKLHLGIWYN DIPRLTVVWV ANRETPITNS SSSPPSLSLT
110 120 130 140 150
NTSNLVLSDA SGRVLWTTNI TGSVSPSPPA TGVAAVLLDT GNLVVRTPNG
160 170 180 190 200
TTLWQSFDHP TDTFLPGMKI WIKSSNHRER HAERMVVSWK GPDDPSPGSF
210 220 230 240 250
TYGADPNTSL QYAPWTGFTV DGEYQVNSSA YIYVAIVNTE EDTYISYSLS
260 270 280 290 300
DGATHTRYVL TYAGEYQLQS WNSSSSAWPV LGQWPTWECN HYGQCGPYGY
310 320 330 340 350
CDSTMAAPTC RCLDGFEPTN PEEWSGGRFS RGYRRKEALR CGDGDGFLAL
360 370 380 390 400
PGMKSPDKFV LVRNRTSEEC AAECAKNCSC VAYAYADLSS SGTKGGMTRC
410 420 430 440 450
LIWAGELIDT EKMGDMAGGE TLYLRSAGLD DPGNRRKAKT KLMKILLSAV
460 470 480 490 500
LVSSIVILAG IIFACFKFQA RRRNREDHKK LGLILGDTGT SEGLGEGNTA
510 520 530 540 550
QDFGFPFVRF EDIVAATLDK EEFRNEVVLI ARLQHRNLVR LLSCSVKGEE
560 570 580 590 600
KMLIYEYLPN KSLDDSRLTI IHRDLKAANV LLDGEMRPKI ADFGMARLFN
610 620 630 640 650
DNQTKANTHR VVGTYGYMAP EYAMEGIFSI KSDVYSFGVL LVEIVTGRRR
660 670 680 690 700
SSMDDIIGFS NLIIYAWNMW KEGKTGCLAD SSIMDTLALL YVQENPDDRP
710 720 730 740 750
HMSSVVFSLK NRCVTLPRPN QPAYFAQRST EMDQIRDNIY NLLNTLTLTN
760
IEPRYFFLKI L
Length:761
Mass (Da):84,323
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAFACCB3E771F94B8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AGNK02001227 Genomic DNA No translation available.

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
KQL25609; KQL25609; SETIT_033310mg

Gramene; a comparative resource for plants

More...
Gramenei
KQL25609; KQL25609; SETIT_033310mg

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGNK02001227 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblPlantsiKQL25609; KQL25609; SETIT_033310mg
GrameneiKQL25609; KQL25609; SETIT_033310mg

Phylogenomic databases

eggNOGiCOG0515 LUCA
OMAiTKANTHR

Family and domain databases

CDDicd00028 B_lectin, 1 hit
Gene3Di2.90.10.10, 1 hit
InterProiView protein in InterPro
IPR001480 Bulb-type_lectin_dom
IPR036426 Bulb-type_lectin_dom_sf
IPR000742 EGF-like_dom
IPR011009 Kinase-like_dom_sf
IPR003609 Pan_app
IPR000719 Prot_kinase_dom
IPR000858 S_locus_glycoprot_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
IPR024171 SRK-like_kinase
PfamiView protein in Pfam
PF01453 B_lectin, 1 hit
PF08276 PAN_2, 1 hit
PF07714 Pkinase_Tyr, 1 hit
PF00954 S_locus_glycop, 1 hit
PIRSFiPIRSF000641 SRK, 3 hits
SMARTiView protein in SMART
SM00108 B_lectin, 1 hit
SM00473 PAN_AP, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF51110 SSF51110, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50927 BULB_LECTIN, 1 hit
PS50026 EGF_3, 1 hit
PS50948 PAN, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK4A357_SETIT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K4A357
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: October 16, 2019
This is version 44 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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