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Entry version 40 (11 Dec 2019)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene

SETIT_8G160000v2

Organism
Setaria italica (Foxtail millet) (Panicum italicum)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: GO_Central

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SETIT_8G160000v2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSetaria italica (Foxtail millet) (Panicum italicum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4555 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaePanicodaePaniceaeCenchrinaeSetaria
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000004995 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VIII

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4555.Si025839m

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini43 – 91SANTInterPro annotationAdd BLAST49
Domaini623 – 724DIRPInterPro annotationAdd BLAST102

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni116 – 165DisorderedSequence analysisAdd BLAST50
Regioni181 – 224DisorderedSequence analysisAdd BLAST44
Regioni239 – 275DisorderedSequence analysisAdd BLAST37
Regioni306 – 385DisorderedSequence analysisAdd BLAST80
Regioni412 – 587DisorderedSequence analysisAdd BLAST176
Regioni1028 – 1071DisorderedSequence analysisAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili868 – 891Sequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi141 – 165PolarSequence analysisAdd BLAST25
Compositional biasi198 – 222PolyampholyteSequence analysisAdd BLAST25
Compositional biasi319 – 335BasicSequence analysisAdd BLAST17
Compositional biasi336 – 370PolyampholyteSequence analysisAdd BLAST35
Compositional biasi452 – 489PolyampholyteSequence analysisAdd BLAST38
Compositional biasi501 – 542PolyampholyteSequence analysisAdd BLAST42
Compositional biasi543 – 558PolarSequence analysisAdd BLAST16
Compositional biasi568 – 587PolarSequence analysisAdd BLAST20
Compositional biasi1040 – 1071PolarSequence analysisAdd BLAST32

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1019 Eukaryota
ENOG410YA1T LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
MQAMSSL

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167 SANT, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028306 ALY_plant
IPR033471 DIRP
IPR009057 Homeobox-like_sf
IPR010561 LIN-9/ALY1
IPR001005 SANT/Myb

The PANTHER Classification System

More...
PANTHERi
PTHR21689 PTHR21689, 1 hit
PTHR21689:SF5 PTHR21689:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06584 DIRP, 1 hit
PF00249 Myb_DNA-binding, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01135 DIRP, 1 hit
SM00717 SANT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

K3ZGY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASARKVRNS NKRYAKINDD WKIEDTASVP KSKVRKKKLS DMLGPQWSKD
60 70 80 90 100
ELERFYSAYR KYGKDWRKIA GAIRDRTSDM VEALYNMNKA YLSLPEGTAT
110 120 130 140 150
AAGLIAMMTD HYNILDGSNS DHESNDSPKT SRKPQKRGRA KFQSVSKTSD
160 170 180 190 200
TRYPDQLQSQ PASSSYGCLS LLKKKRSGDL FVGNRPRAVG KRTPRVPVAS
210 220 230 240 250
MYHRDERGAP HRQAKPDSNN GDDEGAHVAA LALAEVYQRG GSPQVSQTPG
260 270 280 290 300
RSGDRMFLSP IKSSDRKNAD SEMGSSKLHG FQLDADYPEA SLGSREAETG
310 320 330 340 350
DYTKGASYLM TNKGSPSGKP QKKVKRSQKR RKKAVRKTGD QFEYDREACS
360 370 380 390 400
GTEEGHSARK AKEEPELEAL GRKTAWPSST SNKRSRQLFF DDDISALDAL
410 420 430 440 450
HTLADLSVNI LQPSSVVESE SSAQIKDENK DNDSDGKPSI PAAVSVYEQK
460 470 480 490 500
DYSKSMAKKL KRQSEIASTD MVTRKKAKLA KDPHHDGSTT SEVKQQACTC
510 520 530 540 550
GVKTEKKKRK SSTGKVSKDE KNILKDVEKT EVSAEEGKVS SNKETTARGA
560 570 580 590 600
TPPQADLTSK VKSRRKGGIQ KSLTQECKPT EGADDSGSDK LSYSLSNIID
610 620 630 640 650
VKDKLSHCLS SRLLRRWCMF EWFYSAIDYP WFAKSEFVEY LNHVKLGHVP
660 670 680 690 700
RLTRVEWGVI RSSLGKPRRL SKQFLCEERE KLSQYRDSVR QHYAELRSGI
710 720 730 740 750
REGLPTDLAR PLAVGQRVIA CHPRTRELHD GNVLTVDDNR CRVQFDRPEL
760 770 780 790 800
GVEFVMDIDC MPLHPPENFP ESLRQQNIVN EYYSRLSEAN EDQMKELGNG
810 820 830 840 850
GGARFTSNLN GADATFHIPP GHPISTLMKQ AKAKATVNEV TVATQQAIYN
860 870 880 890 900
QPSTLSQIQE READIRALAE LSRALDKKEA LLVELRHMNE EVSGKQRDGE
910 920 930 940 950
IIRDLEHFRK QYAMVLVQLR DSNDQVAGAL LSLRQRNTYH GNPVQSYPKS
960 970 980 990 1000
MENGIAFAGA PDPYNLFGYI NPESGSQVIE VIETSKCRAK MMVDVAIQAM
1010 1020 1030 1040 1050
CKVSEGENPF AKIGEALDNF NSRGTGSGSS ILGIRRIPPD SGQSNASYQE
1060 1070 1080 1090 1100
NGTPAPATNN SSRLPNGGNS DGQFPNELIS SCVAMMLMIK NCTEKQYHPA
1110 1120 1130 1140
EVAHILDSAL SGLQPCSSQN IPIFREIEMC MGIIKNQMLA LIPTASG
Length:1,147
Mass (Da):127,362
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC016F68A1EC24A54
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A368S8A8A0A368S8A8_SETIT
Uncharacterized protein
SETIT_8G160000v2
1,156Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A368S889A0A368S889_SETIT
Uncharacterized protein
SETIT_8G160000v2
1,152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A368S8F5A0A368S8F5_SETIT
Uncharacterized protein
SETIT_8G160000v2
1,143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AGNK02005059 Genomic DNA No translation available.
CM003535 Genomic DNA Translation: RCV38653.1
CM003535 Genomic DNA Translation: RCV38654.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
KQK95035; KQK95035; SETIT_025839mg

Gramene; a comparative resource for plants

More...
Gramenei
KQK95035; KQK95035; SETIT_025839mg

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGNK02005059 Genomic DNA No translation available.
CM003535 Genomic DNA Translation: RCV38653.1
CM003535 Genomic DNA Translation: RCV38654.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4555.Si025839m

Genome annotation databases

EnsemblPlantsiKQK95035; KQK95035; SETIT_025839mg
GrameneiKQK95035; KQK95035; SETIT_025839mg

Phylogenomic databases

eggNOGiKOG1019 Eukaryota
ENOG410YA1T LUCA
OMAiMQAMSSL

Family and domain databases

CDDicd00167 SANT, 1 hit
InterProiView protein in InterPro
IPR028306 ALY_plant
IPR033471 DIRP
IPR009057 Homeobox-like_sf
IPR010561 LIN-9/ALY1
IPR001005 SANT/Myb
PANTHERiPTHR21689 PTHR21689, 1 hit
PTHR21689:SF5 PTHR21689:SF5, 1 hit
PfamiView protein in Pfam
PF06584 DIRP, 1 hit
PF00249 Myb_DNA-binding, 1 hit
SMARTiView protein in SMART
SM01135 DIRP, 1 hit
SM00717 SANT, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK3ZGY7_SETIT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K3ZGY7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: December 11, 2019
This is version 40 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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