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Protein

DNA ligase

Gene

MPH_03350

Organism
Macrophomina phaseolina (strain MS6) (Charcoal rot fungus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:MPH_03350Imported
OrganismiMacrophomina phaseolina (strain MS6) (Charcoal rot fungus)Imported
Taxonomic identifieri1126212 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesDothideomycetes incertae sedisBotryosphaerialesBotryosphaeriaceaeMacrophomina
Proteomesi
  • UP000007129 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini713 – 850DNA_LIGASE_A3InterPro annotationAdd BLAST138

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili263 – 283Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiK2RAJ3
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 2 hits
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

K2RAJ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLFHKVHAL PPSLLLSRSL FPSLSFAKSP RPVSALYFST SPQLLTRAAL
60 70 80 90 100
CNSMAPKQAT LGYVKPNQTT LGKFFGKQNG EGAPPQQSKL AFSTKPKPAP
110 120 130 140 150
TKSEQRQDNK ASEGTVRTEE GDVGQERAGN VSPEKKEDVE MKDEVKSDED
160 170 180 190 200
AVAGDSDSAH SKKRARNESD EEDDEPVSNK RTAKKARQSR KPDSSTETST
210 220 230 240 250
KPQKKTSKTK AKVKEEVDDD ASDHPPSPKT AKAKSKKESS KTAHEEVETK
260 270 280 290 300
SAKRAASPPK ATTKALEAEA SSADSAAAES EKEDEDLVSS EDEKPAVAAK
310 320 330 340 350
AREKVQSTLK GSDNELYPDW KAGEPVPYAA LCAAFSKIEM TTKRLEISAY
360 370 380 390 400
CSKFFRQVLR LTPEDLLPTV LLMVNKLAAD YAGIELGIGE SLIMKSIGET
410 420 430 440 450
TGRSLAVIKA DQTEIGDLGL VAAKSRSNQP TMFKPKPLTV RGVHKGLLEI
460 470 480 490 500
ATIEGQGSQG RKVAGIKKLL SASDAHLAGK GGRGVDIYKD KGGASEAKFI
510 520 530 540 550
VRMLEGKLRL GLADKSVLVS LAHAMVAYEL DPTGQKVPNT EQLAKGERIL
560 570 580 590 600
KSVYSELPSY EVIIPAMLKH GLSNLREHCK LQPGVPLKPM LAKPTKSITE
610 620 630 640 650
VLDRFEGKHF TCEYKYDGER AQIHFVSHDA AQDYATEAPS AGKTDRGISN
660 670 680 690 700
IFSRNSEDLS KKYPDILAKL PTWVKEGTKS FVLDCETVAW DIDEKKVLPF
710 720 730 740 750
QTLMTRKRKD VKVEDVKVKV CVFAFDLLYL NGQALVNKPF RERRELLHAS
760 770 780 790 800
FSPVEGEFAY AEYGDTNELD EIQELLEKSV KASCEGLMVK MLDGPESSYE
810 820 830 840 850
PSKRSQNWLK VKKDYLSGVG DSLDLVVLGA YFGRGKRTSV YGAFLLACYN
860 870 880 890 900
TTTESYETVC NIGTGFSDEV LASLHEQLSQ HIIDRPKPFY SHSQGNKDQP
910 920 930 940 950
DVWFEPKFVW EVKTADLTLS PRYMAAMDAL GVGKGVSLRF PRFIHQREDK
960 970 980
KPEQATSARQ VAEMYRKQEA VTKNKGPSVD DDFEY
Length:985
Mass (Da):108,473
Last modified:November 28, 2012 - v1
Checksum:i053DD098DC3CDDA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHHD01000163 Genomic DNA Translation: EKG19486.1

Genome annotation databases

EnsemblFungiiEKG19486; EKG19486; MPH_03350

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHHD01000163 Genomic DNA Translation: EKG19486.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEKG19486; EKG19486; MPH_03350

Phylogenomic databases

InParanoidiK2RAJ3
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 2 hits
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK2RAJ3_MACPH
AccessioniPrimary (citable) accession number: K2RAJ3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: December 20, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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