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UniProtKB - K1QVV9 (K1QVV9_CRAGI)

Entry version 37 (10 Feb 2021)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Neuron navigator 2

Gene

CGI_10023552

Organism
Crassostrea gigas (Pacific oyster) (Crassostrea angulata)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.ARBA annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00232

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neuron navigator 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CGI_10023552Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCrassostrea gigas (Pacific oyster) (Crassostrea angulata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29159 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Mollusca › Bivalvia › Autobranchia › Pteriomorphia › Ostreida › Ostreoidea › Ostreidae › Crassostrea
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005408 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

MitochondrionARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		K1QVV9

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini498 – 651AAAInterPro annotationAdd BLAST154

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni50 – 71DisorderedSequence analysisAdd BLAST22
Regioni122 – 143DisorderedSequence analysisAdd BLAST22
Regioni165 – 214DisorderedSequence analysisAdd BLAST50
Regioni322 – 341DisorderedSequence analysisAdd BLAST20
Regioni811 – 830DisorderedSequence analysisAdd BLAST20
Regioni1431 – 1455DisorderedSequence analysisAdd BLAST25
Regioni1778 – 1849DisorderedSequence analysisAdd BLAST72

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili280 – 314Sequence analysisAdd BLAST35
Coiled coili1910 – 1930Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi54 – 71PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1778 – 1831PolarSequence analysisAdd BLAST54
Compositional biasi1832 – 1849AcidicSequence analysisAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the COQ9 family.ARBA annotation
Belongs to the Nav/unc-53 family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, Transit peptideARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_232732_0_0_1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003593, AAA+_ATPase
IPR016024, ARM-type_fold
IPR003959, ATPase_AAA_core
IPR013718, COQ9
IPR039041, Nav/unc-53
IPR027417, P-loop_NTPase
IPR012762, Ubiq_biosynth_COQ9
IPR013877, YAP-bd/ALF4/Glomulin

The PANTHER Classification System

More...PANTHERi		PTHR12784, PTHR12784, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00004, AAA, 1 hit
PF08511, COQ9, 1 hit
PF08568, Kinetochor_Ybp2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00382, AAA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR02396, diverge_rpsU, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K1QVV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPSKDNMQE KSEYESLYDS AGNEGYMAHV VAAFEQSLSN MTARLQHLTS 
        60         70         80         90        100
TAEQKASDKV RLRSKQEKDS ELNELRATIE ALKRQSGLSI PDPTILSPGA 
       110        120        130        140        150
GRRHTSPGMV NTNDYISSPL HQIHHQSPHH GNRPGFNTLP MPTEGRITRQ 
       160        170        180        190        200
LSTDSVSSIN SLSSACSTAS QQSAATDGEA GRRKKKKGWL RSSFSKAFSR 
       210        220        230        240        250
KKNKSGSMSD CELDMGNSRP NFSAPNSPLL QIHMPNGQGL IKGSHSSSAL 
       260        270        280        290        300
YEAEDASSVL ELKKQLRDKD MKLTDIRLEA LSSAHQLEQL RETMNKMKNE 
       310        320        330        340        350
MSALKADNDR LQRMMHVRPL NSSQNSIAHN RTSSESLERS LSITEQPSLE 
       360        370        380        390        400
MLLSETPDRD GKRVTMTVYL GSNPDPLREG VERPAEVLIG SLSVSGKTKW 
       410        420        430        440        450
DILDNIVRKI LKEYVLRVDP VTNLGLSAES VFSYHIAEII RTKDAELPEL 
       460        470        480        490        500
LPIGYLVGDT MQIGICLKGT RQNSVDSLAF ETLIPKSIVQ RYVSLLLEHR 
       510        520        530        540        550
RIILCGPSGT GKTYLAQKLA EHLVLRSGKE LTAGSVATFN VDHKSAKELR 
       560        570        580        590        600
QYLANIAEQC ENTGVGELPS VIILDNLHHV GSLGEVFNGF LSVKYQKCPY 
       610        620        630        640        650
IIGTMNQATC STTNLQLHHN FRWVLCANHM EPVKGFLGRY LRRKLVEAEV 
       660        670        680        690        700
RTGIRNNDLN KIIDWVPKVW LHLNKFLETH SSSDVTIGPR LFLSCPMEIS 
       710        720        730        740        750
GSKVWFTDLW NYSIVPYLLE AVREGLQVYG KRAPWEDPTD WVLESYPWAT 
       760        770        780        790        800
AKDEDPSLLK IRPEDVGYDT QGVISTSSGV ALKSKSSDST NHMEPSTDPL 
       810        820        830        840        850
YNMIKRLQEA ANYSSSQSGQ DDDSASATTQ ECISRHGLTF EIYSNQTQIE 
       860        870        880        890        900
RRNRGRTSGQ VQRDLLQSTP SWVARFTKFP LQRKAPMDQP MQVKLLKNKE 
       910        920        930        940        950
RRVVEMEELL KYQSETQTKK IKLQMTGVFE ELMTFHVQKN IQKNKERMDE 
       960        970        980        990       1000
VLQELMTFHD EQKMIINRRQ MRGVFKELKM YHSQQKIRTS KKLMARVFAE 
      1010       1020       1030       1040       1050
LTTFHAQQRT MQIKEKMRQV CAELMTIHAQ RETQTQTQKV MKRMQLVFAE 
      1060       1070       1080       1090       1100
LLQTNSERKK LKLLEEEGYE EFVPRKLFFF NIISFKQTDD DHLRQGPIYP 
      1110       1120       1130       1140       1150
DLSSPVALSK LAPPQESLDA KAAVVDDEND DEEMDKMEVA FKTKTTPLSY 
      1160       1170       1180       1190       1200
SHNHHFINIM DHLMDVEVME KAADAETALK QVKECIKFKD SKGLKTVILE 
      1210       1220       1230       1240       1250
HKLKDQSVFW EIASELTANL TEENLEQHEY FFETCQRCMN YVIANGNPKE 
      1260       1270       1280       1290       1300
LLLAVLEQAD SFKDDQKFKC ILENVQKILL KLPSKRHHSL DVTLETLSAH 
      1310       1320       1330       1340       1350
IEAIPQAKDH NLDHEERKLL EMDPSVMRAT DVVLCYLEFL SPFVEEVSMR 
      1360       1370       1380       1390       1400
NPKVTFSKST PQVQLLVKYL MKLLCHPLYH LDMTFKPKEQ EEKEKSYSRV 
      1410       1420       1430       1440       1450
CAERLIDQLA QLCPNFFALI EDETKKRSMQ AKLKESEARE DEENEELEEE 
      1460       1470       1480       1490       1500
EGDDKVKDWK EDKLIPEKSL ACLSYLVLAE GLGLDQMPAV YNHKFMLRFH 
      1510       1520       1530       1540       1550
LPFIKSFLED QHSIVKLKGV LLLEKLMFVI LPMSFTHYEL DNDFYKDILN 
      1560       1570       1580       1590       1600
LLISTMTHCQ NKDIRKSCVP IYSNFFGMFS LQGRHRLYET VFNTCKHSGV 
      1610       1620       1630       1640       1650
VGHTLSLYKE QVDSLLKKGE GPENIFLGKN LIRVFKLVSV IPDGVTTDLL 
      1660       1670       1680       1690       1700
ENSDRILSVL NFVRYLVLRD NPSENRTGFW ELYPNLDKEF FEPLRQAIIL 
      1710       1720       1730       1740       1750
SKGHYNLDLE DVRKGNPLPT ENTEFSVNVG GERLGPVSRE QQIQVIESAL 
      1760       1770       1780       1790       1800
NTFDMMDSIL SRTIELADAQ KRTLSRCNRN GGRFMCTSTG DRNPPMDTSS 
      1810       1820       1830       1840       1850
GPGGSASSQT SNGGYNTQRT GQGAQYSDEL DNSEDLVNEV EEEEMPEETE 
      1860       1870       1880       1890       1900
EEYQTKQAVL KASLPFVHQY GWTKKAIVAG AESLGMPSMV HGMFPRGGAE 
      1910       1920       1930       1940       1950
LVFYFYEESN KELESFLKQK VKELKEKDEK IKTGPFIHDA IETRLRMIIP 
      1960       1970       1980       1990       2000
YIDKWPQAMA IQTLPQNAVQ SWTNLSRVVD DIWFYAGDKS NDFNWYTKRG 
      2010       2020       2030       2040       2050
SLAAIYKSTE IYLIQDRSED YTDTWNFLEN RLEDVVSAGH LARNACIQVY 
      2060       2070 
VFLKKLVICF SFKKPIQFYQ KVLKDFV
Length:2,077
Mass (Da):237,204
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF03AA4B1E8FCE26
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AFTI01009360 Genomic DNA No translation available.
AFTI01009361 Genomic DNA No translation available.
JH816961 Genomic DNA Translation: EKC37788.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		EKC37788; EKC37788; CGI_10023552

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AFTI01009360 Genomic DNA No translation available.
AFTI01009361 Genomic DNA No translation available.
JH816961 Genomic DNA Translation: EKC37788.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PRIDEiK1QVV9

Genome annotation databases

EnsemblMetazoaiEKC37788; EKC37788; CGI_10023552

Phylogenomic databases

HOGENOMiCLU_232732_0_0_1

Enzyme and pathway databases

UniPathwayiUPA00232

Family and domain databases

InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR016024, ARM-type_fold
IPR003959, ATPase_AAA_core
IPR013718, COQ9
IPR039041, Nav/unc-53
IPR027417, P-loop_NTPase
IPR012762, Ubiq_biosynth_COQ9
IPR013877, YAP-bd/ALF4/Glomulin
PANTHERiPTHR12784, PTHR12784, 1 hit
PfamiView protein in Pfam
PF00004, AAA, 1 hit
PF08511, COQ9, 1 hit
PF08568, Kinetochor_Ybp2, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
SSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR02396, diverge_rpsU, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK1QVV9_CRAGI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K1QVV9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: February 10, 2021
This is version 37 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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