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Entry version 30 (10 Feb 2021)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Coiled-coil domain-containing protein 45

Gene

CGI_10027483

Organism
Crassostrea gigas (Pacific oyster) (Crassostrea angulata)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Coiled-coil domain-containing protein 45Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CGI_10027483Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCrassostrea gigas (Pacific oyster) (Crassostrea angulata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29159 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaMolluscaBivalviaAutobranchiaPteriomorphiaOstreidaOstreoideaOstreidaeCrassostrea
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005408 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
K1PYC5

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini102 – 157DUF5745InterPro annotationAdd BLAST56

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni206 – 257DisorderedSequence analysisAdd BLAST52
Regioni305 – 328DisorderedSequence analysisAdd BLAST24
Regioni370 – 409DisorderedSequence analysisAdd BLAST40
Regioni421 – 479DisorderedSequence analysisAdd BLAST59
Regioni515 – 535DisorderedSequence analysisAdd BLAST21
Regioni601 – 635DisorderedSequence analysisAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili677 – 711Sequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi238 – 257PolarSequence analysisAdd BLAST20
Compositional biasi370 – 391PolarSequence analysisAdd BLAST22
Compositional biasi444 – 464PolyampholyteSequence analysisAdd BLAST21
Compositional biasi465 – 479PolarSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_018428_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
K1PYC5

Identification of Orthologs from Complete Genome Data

More...
OMAi
KHSQPWK

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026619, CEP95
IPR036872, CH_dom_sf
IPR044039, DUF5745

The PANTHER Classification System

More...
PANTHERi
PTHR22545, PTHR22545, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF19016, DUF5745, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K1PYC5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIVSILTTQI NGVIAVGSPS NATAGTGASV DEFFNMYMVP FKIKMGPKER
60 70 80 90 100
LNQEDIKIVR QANLLLEQLN AGSSLGCVED INAAVYVTLF EGLCGEKLHG
110 120 130 140 150
VIQKPISRED EIQNIQLVID ILSRDILHTS LAHITGREVV DGNRESIWNL
160 170 180 190 200
LEIFGGLLEY ILNKIDSDAS TDGEGDLDEL EDDPDAVEPD VIDRILEREL
210 220 230 240 250
QRNYSLEGSP DRLTPKASPI RRRSPIRSPE RGRRTLLSPS KLPQSSEPSP
260 270 280 290 300
KKSLNSTNEL IKEGENLQKE LLSDRYKPMK TAAEIREDLA RHRRELGLTR
310 320 330 340 350
DPFSDLVPVP ATSDKRQSNL KTGDVKGEES YKSLKDMVES TAAMAEEAVN
360 370 380 390 400
CSPNRARTIL RSMESDYNIE QFRSTYPSPK KTQNKSPPRK TKSPARNSDD
410 420 430 440 450
DFFSDSELNP SNAKRKVSFL VERSTTSESS PSFLRSAPRY KPKTKTAWTE
460 470 480 490 500
KTEGTNKPGR PRQDNTQRRG TSGDSSLFDF EKNPANFSYD EYLKKQFHEI
510 520 530 540 550
IDDVLSIDEA MPPRFRSRND QQKHHISKLG SKSKGNYSIS DTQKLLKNEK
560 570 580 590 600
GVNKRKVDRI YQEDLDELQN EAEYDLSKDR KDARQVEDEY KKKVLTGAKT
610 620 630 640 650
STKPKETGMK KKTPIQKHSV CSKAKRKSPS GVTAVPKQRL TIKDDEDILP
660 670 680 690 700
ILLKEFPHLH LSLHTWHELW RKGIHQIEQV TRANQEVRRK KSKAKSELEE
710 720 730 740 750
AEKRHEIMVN IMKKEIEHGQ RMKEIKERHK QTVVAKNMIQ EKRAQSARSR
760 770 780 790 800
KYYDDYQVRM RSKMLKRRTK EEMIFRKLFK DGLDIQKDRV RELKKYAKEQ
810 820 830 840 850
RDTQASTQRN EIESMENYYR DQFEMLAESI TKERKEILVR EKAQQKVLGQ
860 870 880 890 900
MKKELRHKME SEIRLLQDQL VRDDDDAYFR QLDADRVIHN LQLAKYHANN

V
Length:901
Mass (Da):103,950
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF067DC7D482AC1FC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AFTI01013734 Genomic DNA No translation available.
JH817548 Genomic DNA Translation: EKC29267.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
EKC29267; EKC29267; CGI_10027483

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AFTI01013734 Genomic DNA No translation available.
JH817548 Genomic DNA Translation: EKC29267.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiK1PYC5

Genome annotation databases

EnsemblMetazoaiEKC29267; EKC29267; CGI_10027483

Phylogenomic databases

HOGENOMiCLU_018428_1_0_1
InParanoidiK1PYC5
OMAiKHSQPWK

Family and domain databases

Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR026619, CEP95
IPR036872, CH_dom_sf
IPR044039, DUF5745
PANTHERiPTHR22545, PTHR22545, 1 hit
PfamiView protein in Pfam
PF19016, DUF5745, 1 hit
SUPFAMiSSF47576, SSF47576, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK1PYC5_CRAGI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K1PYC5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: February 10, 2021
This is version 30 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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