Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 41 (10 Feb 2021)
Sequence version 1 (28 Nov 2012)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Dynein heavy chain 5, axonemal

Gene

CGI_10017921

Organism
Crassostrea gigas (Pacific oyster) (Crassostrea angulata)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor proteinARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dynein heavy chain 5, axonemalImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CGI_10017921Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCrassostrea gigas (Pacific oyster) (Crassostrea angulata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29159 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaMolluscaBivalviaAutobranchiaPteriomorphiaOstreidaOstreoideaOstreidaeCrassostrea
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005408 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, CiliumARBA annotation, Cytoplasm, CytoskeletonARBA annotation, DyneinARBA annotation, MicrotubuleARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
K1PX83

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1976 – 2112AAAInterPro annotationAdd BLAST137
Domaini2586 – 2784AAAInterPro annotationAdd BLAST199

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni900 – 944DisorderedSequence analysisAdd BLAST45
Regioni1053 – 1093DisorderedSequence analysisAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili8 – 30Sequence analysisAdd BLAST23
Coiled coili258 – 282Sequence analysisAdd BLAST25
Coiled coili3253 – 3305Sequence analysisAdd BLAST53
Coiled coili3473 – 3528Sequence analysisAdd BLAST56
Coiled coili3536 – 3556Sequence analysisAdd BLAST21
Coiled coili3779 – 3806Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi912 – 932PolarSequence analysisAdd BLAST21
Compositional biasi1053 – 1072PolyampholyteSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein heavy chain family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000038_9_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
K1PX83

Identification of Orthologs from Complete Genome Data

More...
OMAi
FQKRDRY

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR041589, DNAH3_AAA_lid_1
IPR042228, Dynein_2_C
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041466, Dynein_AAA5_ext
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013594, Dynein_heavy_dom-1
IPR013602, Dynein_heavy_dom-2
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676, PTHR10676, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 1 hit
PF12781, AAA_9, 1 hit
PF17857, AAA_lid_1, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08385, DHC_N1, 1 hit
PF08393, DHC_N2, 1 hit
PF17852, Dynein_AAA_lid, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K1PX83-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATSTVKAN RELQMQKLKE EREAKRAHLD ERHFYILQTV ADSLGLELTE
60 70 80 90 100
VEDAILEGNQ IEMMDQFLSP NSVSQLLFYY QEPEHVEPVD HLRVGPPQAK
110 120 130 140 150
VSKTSKPKVF VTNGRDTPLR GVALVFTKVA EADVTITETN IMKEVTFTRL
160 170 180 190 200
DTSGNGKNGS GLLHAVETLL SSIFIPALKN LDKGWGALGT PSGEQVRQDF
210 220 230 240 250
LNTLDSFVSV LVGAQESLEE KVTLKPCETY DLSKIQTPAD YQAVANSSEA
260 270 280 290 300
LEGIENCMNV WLKQLEQVLA ESEQMRKEAD DIGPRAELDH WKKRMSRFNY
310 320 330 340 350
LLDQIKGPDV KAVLGVLHAS QSKLIKQWQE HDRRITDLAN EARDNVKFLY
360 370 380 390 400
TLEKFCDPLY NSDPVGMLEG IPGLINAIRM IHSISRYYNT SERMTSLFVK
410 420 430 440 450
ITNQMITACK SYISCQKTET VWTQNQADVV RKLNDCIKLN EEYQRCFHKT
460 470 480 490 500
KEKLEKMPNE RPFEFSEMYI FGKFDTFTRR LKKIIEMFET ISMYSHLSES
510 520 530 540 550
KIEGIEQSAT RFNVIVTNMK KKPYDFLDQR KTEFELDFDE FKRMVAELHQ
560 570 580 590 600
NIQMFMDQKF EKIVSTTRAL VLLQRFEKLN LPGLGIYDKY QRILSHYGKD
610 620 630 640 650
IENVSKLYQK NKNDPPVARD LPPIAGKIAW ARQLYRRIQE PMEVFKQQGK
660 670 680 690 700
LLEMPEAKRI IKNFNKLAKV LLEFEMLYHR GWLRQIEAAR SGLQASLLIK
710 720 730 740 750
HPETAELFVN FDPQILTMVR ETECMARLGL EIPPLAITMR AKQTEYKDNY
760 770 780 790 800
SALQMLLQEN KRVRNKIPTA FESLMGPHVS KVDKRLEPGL SKLSWTSLNI
810 820 830 840 850
QEYIQEVYSV LGELELLMDR AHDLMEFRID AVLKEMSTTK LCQLPEDEPW
860 870 880 890 900
LCDAFLENTQ MLCAKGAVAL QTKSLVVEEA ANELINMLCP VDFEDEDEKI
910 920 930 940 950
EMEEDEEEQR SQAGSPTGSQ GARTSSRKSR PVSSKAHLVA KKKREMRENI
960 970 980 990 1000
EEAANELLAH FNHRNQDALM KVTKNTLESL RKRITSSSMV HYLGDSGGFG
1010 1020 1030 1040 1050
DAKKDSGPFF KTFATLAIPN IVMQPALDEV QQTVNKAAQM IISVSKGVAK
1060 1070 1080 1090 1100
WSEERKRPQK SAVDREHAVA ADRRQSVVSA ASDAAGEKKE EETEMKNYTI
1110 1120 1130 1140 1150
TQQAKNYFKA VSENKEVTKL VSLLSTSINS TKKEVTTALD RFSGYHPIWE
1160 1170 1180 1190 1200
KDREDDLVEF NKEDPKLSEY EAKIKHYEEL EVEINGLPEF YDVGPIALYT
1210 1220 1230 1240 1250
ENLKLGLTTE TKAWKLHYGK ACNQKYSMEM ERIFTFIEDL TKRLSRPLKD
1260 1270 1280 1290 1300
LDDIRFAMAA LKEIRDDEIR IDMLIGPIEE SYAMLIKHDL PVNKEETEKC
1310 1320 1330 1340 1350
DTLRYSWEKL QVQTSEVQTE LLQVQPQFKS ELIENVKTFN TDCSDFYSTY
1360 1370 1380 1390 1400
DTQGPMCAGV PPREASDRLI IFQNNFDVLY KKFITYTGGE ELFGLPVSDY
1410 1420 1430 1440 1450
PKLGQIKKEL NLLQKLYSLY NNVLETVHGY YDILWADINI EKINNELLEF
1460 1470 1480 1490 1500
QNKCRKLPRA LKDWPAFEDL KKTIDNFNEM VPLLELMTNK AMKPRHWNRM
1510 1520 1530 1540 1550
AEVTSHVFDV ESDNFALKNI LEAPLLEFKE EIEDICISAV KEKDIEAKLK
1560 1570 1580 1590 1600
QVIADWNNKE FTFAQFKNRG ELLLRGDNTS EIVSLMEDSL MVLSSLLSNR
1610 1620 1630 1640 1650
YNAPFKKNIQ LWVQNLTNSS EIIENWMTVQ NLWVYLEAVF VGGDIAKQLP
1660 1670 1680 1690 1700
KEAKRFSNID KSWIKIMTRA HETPNVVQCC VGDETLMQLL PHLLEQLELC
1710 1720 1730 1740 1750
QKSLTGYLEK KRLLFPRFFF VSDPALLEIL GQASDPHTIQ AHLLSVFDNL
1760 1770 1780 1790 1800
KTVKFHEKFY DQILAIYSSE NETIDLEKPV KAEGNVENWL MSLMLMAQKS
1810 1820 1830 1840 1850
LHGVIRTAAM SIQDSSFQLL EFLNMFPAQV GILGIQMIWT RDSTEALTHA
1860 1870 1880 1890 1900
RYDRKIMQQT NQAFLDLLNI LINQTTQDLT KVERTKFETL ITIHVHQKDI
1910 1920 1930 1940 1950
FDDLCRMHVK SPTDFEWLKQ SRFYFLEDQD KCQISVTDVD FIYQNEFLGC
1960 1970 1980 1990 2000
TERLVITPLT DRCYITLAQA LGMSMGGAPA GPAGTGKTET TKDMGRCLGK
2010 2020 2030 2040 2050
YVVVFNCSDQ MDFRGLGRIY KGLAQSGSWG CFDEFNRIDL PVLSVAAQQI
2060 2070 2080 2090 2100
AIVLGAKKER KKAFIFTDGD NVTLSPEFGI FLTMNPGYAG RQELPENLKI
2110 2120 2130 2140 2150
NFRTVAMMVP DRQIIIRVKL ASVGFLDNIT LARKFYTLYK LCEEQLTKQV
2160 2170 2180 2190 2200
HYDFGLRNIL SCLRTLGTVK RQNKDDPEAM SVMRVLRDMN LSKLVDQDEP
2210 2220 2230 2240 2250
LFLSLINDLF PGITLDKGGY PDLEGAIARQ IDEAKLVAHP PWTLKLIQLF
2260 2270 2280 2290 2300
ETQRVRHGMM TLGPSGAGKT CCIHILMKAM TDCGEPHKEL RMNPKAITAP
2310 2320 2330 2340 2350
QMFGRLDVAT NDWTDGIFST LWRRTLRAKK GEHIWLVLDG PVDAIWIENL
2360 2370 2380 2390 2400
NSVLDDNKTL TLANGDRIPM APNCKIIFEP HNIDNASPAT VSRNGMVYMS
2410 2420 2430 2440 2450
SSGLDWKPIL QCWLNSRPVN EQAIIMDLFE RSFPLVLQYA VQNLTFKMEV
2460 2470 2480 2490 2500
LEAFIISQAC KLLEGLIPSK DDKDSGSVSQ SHYEHLYIFT LMWTIGAFLE
2510 2520 2530 2540 2550
WDDRIKVEEF MRSNDDIVLD LPPTNRDADE TMFDYMVDTN GQWQHWSNKV
2560 2570 2580 2590 2600
EPYHYPTDST PEYGSILVPM VDNVRTEFLI NTISKQGKAV LLIGEQGTAK
2610 2620 2630 2640 2650
TVMINGYMGK YNPEYHLGQS LNFSSATTPL MFQRTVESYV DKRVGSTYGP
2660 2670 2680 2690 2700
PAGKKMTIFV DDINMPVINE WGDQIANEIV RQLMEYKGFY NLEKPGDFTN
2710 2720 2730 2740 2750
IADVQFLAAM IQPGGGRNDI PQRLKRQFVI INCTLPSNPS IDKIFSCIGC
2760 2770 2780 2790 2800
GHYITDRGFA KDVIDMTAKL VPITRRLWQL TKIKMLPTPA KFHYIFNLRD
2810 2820 2830 2840 2850
LSRIWQGMIN TECSVIKSEK ELLWLWKHEC SRVIADRFTN FEDQAWFNKT
2860 2870 2880 2890 2900
MSRVINEELS ETHGAMVDST HYFVDFMKFT TAEDGHWFEK TLLRVIGDEL
2910 2920 2930 2940 2950
GEDFLEIVKP TYYFGDFMRD APEATGDEPE DTDFDMPKIY EPIPSFEVLE
2960 2970 2980 2990 3000
ERLQMFLQQY NEGIRGSGMD LVFFKDAMIH LVKVSRIIRT PRGNALLVGV
3010 3020 3030 3040 3050
GGSGKQSLTK LASFIAGYKT FQITLTRSYN VSNLLEDLKY LYRTAGAQGK
3060 3070 3080 3090 3100
GITFIFTDQE IKDEAFLEYL NNVLSSGIVA NLFARDEMDE IMGELIPIMK
3110 3120 3130 3140 3150
KEFPRRPPSN ENLYDYYLTR VRNNLHVVLC FSPVGEKFRA RALKFPGLIS
3160 3170 3180 3190 3200
GCTMDWFQRW PKDALIAVAD HFLSNFNIEC TAEVKKQVIQ TMGLIHDGVA
3210 3220 3230 3240 3250
ESCVSYFQRY RRSTHVTPKS YLSFINGYKT IYSDKKNEIG ELAERMNTGL
3260 3270 3280 3290 3300
EKLIEAGQQV ALLKEELAVK EKELAIASEK ADKVLKEVTV KAQAAEKVKE
3310 3320 3330 3340 3350
QVQKVKDKAQ GIVDAIESDK VIAYEKLEKA RPALEEAEAA LNTIKPADIA
3360 3370 3380 3390 3400
TVRKLGKPPH LIMRIMDSVL LLFQKRVNTV EMDPERPCIK PSWGEALKLM
3410 3420 3430 3440 3450
SGTNFLQTLI NFPKDSINDE TVELLDPYLS QEDYTLEVAK RVCGNVAGLL
3460 3470 3480 3490 3500
SWTRSMAVFF EINKEVLPLK ANLAVQEARL QVAMGDLQKA QAQLDEKEAE
3510 3520 3530 3540 3550
LAKVREMYDQ AMREKQTLLD DAETCRRKMT AAAALINGLQ GERDRWTEQS
3560 3570 3580 3590 3600
KEFRAQIGRL VGDVLVCTAF LSYSGPFNQD FRLLLNQKWF KELKNRKIPC
3610 3620 3630 3640 3650
TLNLSVIDML TDPTVIGEWN LQGLPNDELS TQNGIIVTKA SRYPLLIDPQ
3660 3670 3680 3690 3700
GQGKNWIKNR EAHSELQLTS LNHKYFRTHL EDSMSLGRPL LIEDVAEELD
3710 3720 3730 3740 3750
PALDNVLEKN FIKVGSTLKV KVGDKECDIM KGFSLYITTK LGNPSYTPEV
3760 3770 3780 3790 3800
SAKTSIIDFT VTMKGLEDQL LGRVILTEKA ELESERVKLM EDVQSNKKKM
3810 3820 3830 3840 3850
KELEDNLLYR LTSTKGSLVD DEDLINVLNT TKTTAQDVSQ KLQVAAETQT
3860 3870 3880 3890 3900
KITVAREEFR PVAARGSILY FLIVEMGLVN CMYQTSLKQF LYLFDLSMAR
3910 3920 3930 3940 3950
SAKSPITQKR IQNIIDFMTF EVFKYAVRGL YEEDKNTFTL LLTLKIDLAA
3960 3970 3980 3990 4000
GKIKHEEFMT LIKGGASLDL NVVQPKPHKW IVDLTWLNLV ELSNLHQFSG
4010 4020 4030 4040 4050
ILEQVSRNEK QWRQWFDKEA PEEEVIPDGY NNSLDVFRRL LLVRSWCPDR
4060 4070 4080 4090 4100
TMSQARKYIA DTLGDKYAEG VILDLEKMWS ESNSRTPMVC LLSMGSDPTN
4110 4120 4130 4140 4150
NIEALAKKLK LECRNISMGQ GQEVHARRLM AQGMANGGWL LLQNCHLSLD
4160 4170 4180 4190 4200
YVEEVLDQLI ETETIHQEFR LWVTTEVHKK FPINFLQISI KFTNEPPQGI
4210 4220 4230 4240 4250
KAGLKRTYAG LSQDFLDISN MPQWKPMLYG VAFMHTVVQE RRKFGPLGWN
4260 4270 4280 4290 4300
IPYEFNAADF NASVQFVQNH LDDMDIKKGV NWTCVRYMFG EIQYGGRVTD
4310 4320 4330 4340 4350
DYDKRLLNTF CKVWFGENMF QSNFCFYKGY IIPKCAKMQE YMDYINNLPG
4360 4370 4380 4390 4400
TDTPEAFGLH ANADITYQSK SAKTVLDTIL EIQPKDSSGG GSGETRESIV
4410 4420 4430 4440 4450
YRICDDMLEK LPNDYDPFEV KARLEKMGRL QPMNIFLKQE IDRMQRVISL
4460 4470 4480 4490 4500
VRSTLSDLKL AIDGTIIMSE SLRDALDCMY DARIPKLWQK ISWDSSTLGF
4510 4520 4530 4540 4550
WFTELIDRNG QFHTWCFDGR PVTFWMTGFF NAQGFLTAMR QEVTRAHKGW
4560 4570 4580 4590 4600
ALDGVILHND VTRQMKDDIT TPPSEGVYVY GLFLEGAGWD KRGSKLIEPK
4610 4620 4630 4640 4650
PKVLFEPMPV IHIYAINTTS DKEDTRMYKC PIYKKPRRTD LTYIAAVFLK
4660 4670
TNQNPDHWVL RGVALLCDIK
Length:4,670
Mass (Da):534,909
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44803442857E8A9D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AFTI01016025 Genomic DNA No translation available.
JH817884 Genomic DNA Translation: EKC23674.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
EKC23674; EKC23674; CGI_10017921

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AFTI01016025 Genomic DNA No translation available.
JH817884 Genomic DNA Translation: EKC23674.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiK1PX83

Genome annotation databases

EnsemblMetazoaiEKC23674; EKC23674; CGI_10017921

Phylogenomic databases

HOGENOMiCLU_000038_9_1_1
InParanoidiK1PX83
OMAiFQKRDRY

Family and domain databases

Gene3Di1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR041589, DNAH3_AAA_lid_1
IPR042228, Dynein_2_C
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041466, Dynein_AAA5_ext
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013594, Dynein_heavy_dom-1
IPR013602, Dynein_heavy_dom-2
IPR027417, P-loop_NTPase
PANTHERiPTHR10676, PTHR10676, 2 hits
PfamiView protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 1 hit
PF12781, AAA_9, 1 hit
PF17857, AAA_lid_1, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08385, DHC_N1, 1 hit
PF08393, DHC_N2, 1 hit
PF17852, Dynein_AAA_lid, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK1PX83_CRAGI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K1PX83
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: February 10, 2021
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again