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Entry version 27 (16 Jan 2019)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene

THAOC_15968

Organism
Thalassiosira oceanica (Marine diatom)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:THAOC_15968Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiThalassiosira oceanica (Marine diatom)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri159749 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaStramenopilesBacillariophytaCoscinodiscophyceaeThalassiosirophycidaeThalassiosiralesThalassiosiraceaeThalassiosira

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini286 – 486Helicase ATP-bindingInterPro annotationAdd BLAST201
Domaini618 – 796Helicase C-terminalInterPro annotationAdd BLAST179
Domaini1227 – 1389RNase IIIInterPro annotationAdd BLAST163
Domaini1434 – 1564RNase IIIInterPro annotationAdd BLAST131

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili471 – 491Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00079 HELICc, 1 hit
cd00593 RIBOc, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1520.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005034 Dicer_dimerisation_dom
IPR006935 Helicase/UvrB_N
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000999 RNase_III_dom
IPR036389 RNase_III_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03368 Dicer_dimer, 1 hit
PF00271 Helicase_C, 1 hit
PF04851 ResIII, 1 hit
PF00636 Ribonuclease_3, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SM00535 RIBOc, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit
SSF69065 SSF69065, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS00517 RNASE_3_1, 1 hit
PS50142 RNASE_3_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K0SQP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVRWGVEND EGVDHDVGGG RGPEFEFPTA APRPDELTLS LPRKPRTDFG
60 70 80 90 100
AETGHVADTH TSPEQVPISI SPSEQRHGGG NGDQVEGRFG ALTHPNTQQL
110 120 130 140 150
RDRHGFVALG CNRIPAVLRS AGRPPGPRFC WAAMVAMRYR RCAKQAAAAA
160 170 180 190 200
AEQAVQPAAT PTPCHGPASC ASVQDRRRPA GSAPPVPVHQ CSVQCPRGLG
210 220 230 240 250
CGEDRPTSTG DVPFVFRLPF TVDQQDSAIK QRAAHIQRDL EYIRQHGYEE
260 270 280 290 300
FEALQLQCYS NDNDLQVHEN LGDKFEGSLR NYQVHLLEKC KRSNVIVHLA
310 320 330 340 350
TGMGKTMISI MLIRDYLSKR QAASDTAPAS TIETTLASGQ EGLVSRVYSK
360 370 380 390 400
RQILFLVPSI ALCVQHSDTL RANLNCTVAT ACHTSSHTAR SRDEISRSDV
410 420 430 440 450
IVATHGTAKD LLQHYPDVLA LSNLDLMVID EAHYAGTKDH NYATIMKLFY
460 470 480 490 500
HTLPVGLRPH VLGLTASPLI NAKVSDTAER LQVKLGELER TLDSKLHGFP
510 520 530 540 550
EELADCRKDT KESIVYFDSL LDSFSTKLPE PDMTFLHKSR RKELRQLQAL
560 570 580 590 600
CDDVGLQVTS TYIIALLREI GRNEYDHETI EQFNDLKVYL SQVVIHLNRQ
610 620 630 640 650
VDEGDCGDFS GHTEKMSTLV GLLVDLLKHD DPVGVVFVER RITAIALSHY
660 670 680 690 700
FNQNKPLDHL GVDIRSDSLV RNASKIFKYL SNSSSHDQQV VDQDFLHQTK
710 720 730 740 750
RIRSVINKLR TRETNVLIAT SVVEEGVDVE ACSFIISFDR MKTIKSYIQM
760 770 780 790 800
KGRARQKQAS FYTLVDKCES QILDLPDAQK TEKRIHDFVA SSQTAINLSQ
810 820 830 840 850
PLRDPANAYF DSPYSTEEEA AMHRGKYSTR ISFADLQSAK SLLNRYSMSV
860 870 880 890 900
PIDPSSRSSK EAMTLHMPCY QERENSLSLP SHLPPEFRIV SLPRELRGQN
910 920 930 940 950
AKRKMNLLAL ASIVRLHKLG LLNDRLLPLS MEDMMSWLLK KTLGTIHRVT
960 970 980 990 1000
RTSSSVTYSY PLTAHLYILN QSGSGFEAER QDLLSRGARL NQFALVSLAE
1010 1020 1030 1040 1050
LPEIKAQSSR HRDMGVIDFT IIRRGEVSIS AQQWNEITSF YCTLFNSRWR
1060 1070 1080 1090 1100
RQKKKKKRSF QYDPRLDRCG SASPIPPYAV CLVDTLDQID YTSMKCAVCQ
1110 1120 1130 1140 1150
HAVSKGEMGS QSFPRMWSPN YNPSVSYIVY GPSGNLCRDG FPNTEYTSFL
1160 1170 1180 1190 1200
HYFSEKYGVT TLCPTSKLFV AKRVWDMPHS HSVLGPGAAE EDVAHAANLE
1210 1220 1230 1240 1250
LPAEVCQESP MADPSIVLQS TLLPQFLYLV ERRLTAEAFI RHCQENYEVL
1260 1270 1280 1290 1300
GECLSRAGPD SVMEVLTTKT CRMPQDYERL EWLGDAVLKL VQTDSLLQYS
1310 1320 1330 1340 1350
DTSYLHEGYL HMLRSVMGSN ERLERVAEEC GFNHFILSCP LNREEWRPSR
1360 1370 1380 1390 1400
LQLRKHDDSS TKALPPTPSG KVCADVVEAI LGLIFVQFGF AKSVEVSLEI
1410 1420 1430 1440 1450
GLTFVNADKL SRRDFWSALE DDGELLAFAT NFTGQPISDP RLLHEAVTHP
1460 1470 1480 1490 1500
SCVSKPCRSY QTLEWAGDAA VCLAARNWLF HKKEKLSVPT LVVLESTLTS
1510 1520 1530 1540 1550
NQSLAYIGHL NGVQRIIDHR MSELPGRFES YKFQLRRGLW ATDPPKVIPD
1560 1570 1580 1590 1600
VVESLIGAVH VDQGVEAGQE AAAYVLRPLL DSVSKLLNND LQDWVGVIHP
1610 1620 1630 1640 1650
KQHLYELAAD FVNIKVIKED KCNSMYLKDA VNLCGRKDGN GYVAIVGCKS
1660 1670 1680 1690
IIIGAAIESS KAGAVNVACA LVVEMLKAKP SLVSQLRGMM LS
Length:1,692
Mass (Da):188,880
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBE679AAA457DF478
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AGNL01018284 Genomic DNA Translation: EJK63376.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EJK63376; EJK63376; THAOC_15968

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGNL01018284 Genomic DNA Translation: EJK63376.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEJK63376; EJK63376; THAOC_15968

Family and domain databases

CDDicd00079 HELICc, 1 hit
cd00593 RIBOc, 2 hits
Gene3Di1.10.1520.10, 2 hits
InterProiView protein in InterPro
IPR005034 Dicer_dimerisation_dom
IPR006935 Helicase/UvrB_N
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000999 RNase_III_dom
IPR036389 RNase_III_sf
PfamiView protein in Pfam
PF03368 Dicer_dimer, 1 hit
PF00271 Helicase_C, 1 hit
PF04851 ResIII, 1 hit
PF00636 Ribonuclease_3, 2 hits
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SM00535 RIBOc, 2 hits
SUPFAMiSSF52540 SSF52540, 1 hit
SSF69065 SSF69065, 2 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS00517 RNASE_3_1, 1 hit
PS50142 RNASE_3_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK0SQP6_THAOC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K0SQP6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: January 16, 2019
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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