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Entry version 32 (16 Jan 2019)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene

THAOC_12905

Organism
Thalassiosira oceanica (Marine diatom)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi576 – 583ATPPROSITE-ProRule annotation8
Nucleotide bindingi1225 – 1232ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:THAOC_12905Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiThalassiosira oceanica (Marine diatom)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri159749 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaStramenopilesBacillariophytaCoscinodiscophyceaeThalassiosirophycidaeThalassiosiralesThalassiosiraceaeThalassiosira

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei182 – 203HelicalSequence analysisAdd BLAST22
Transmembranei223 – 246HelicalSequence analysisAdd BLAST24
Transmembranei310 – 336HelicalSequence analysisAdd BLAST27
Transmembranei342 – 360HelicalSequence analysisAdd BLAST19
Transmembranei428 – 447HelicalSequence analysisAdd BLAST20
Transmembranei845 – 866HelicalSequence analysisAdd BLAST22
Transmembranei878 – 898HelicalSequence analysisAdd BLAST21
Transmembranei958 – 991HelicalSequence analysisAdd BLAST34
Transmembranei1066 – 1086HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini188 – 469ABC transmembrane type-1InterPro annotationAdd BLAST282
Domaini542 – 766ABC transporterInterPro annotationAdd BLAST225
Domaini845 – 1105ABC transmembrane type-1InterPro annotationAdd BLAST261
Domaini1191 – 1426ABC transporterInterPro annotationAdd BLAST236

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

K0SML4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
TVEHERRRLQ TTSRRGEVVK PTLLPPLGQG VIVIRPQPGV THRPPGSHTK
60 70 80 90 100
TRVSSMAVLD QEISPSVSTP QQKRRPPHPF TNASLLSKLL FFWPYELMKK
110 120 130 140 150
SDRVDDSNER CGFRVNSGDR APIEEGDLPD VLEQDSSERN LQWFHRIWEA
160 170 180 190 200
EKSRVARRNG STSKQERPSL QRAIAVDFMK SLWYVQPLML CSSAARLVQA
210 220 230 240 250
LALGLLLESF ETSEHNPQAG KGYLWSGVLV VSGFVVLMEH HHVFFYTWRR
260 270 280 290 300
GMQYRIACVA AIYDKSLRLS SCASVELGAT ARRNQKGVSS SSNASSGNVV
310 320 330 340 350
NIATNDVERF LLATLFASYI WWAPIQSVAI LIIGFINVGW SFVAGFGMLC
360 370 380 390 400
VIFAPLQVWL GNRFAKMRSK IAAVTDERVT LVSQAVSGVR VMKMSGWEDK
410 420 430 440 450
FNARIASIRE RECRQIERVN LYRALNESIF FVSSVTISTI IFLLHVANGG
460 470 480 490 500
LLSPRNVFST IVLINVAQME ITKHLSLAVM GVSECQVSIS RIQRYIESPE
510 520 530 540 550
LVKVDSDANA LDEDEIKNAA VVAKNITCYW NGNGRSSSQS TLQSEEEVQV
560 570 580 590 600
PNPLLITALK DVTVHFNTAS LTCVIGAVGS GKSALVQMIA GELTYSSGVL
610 620 630 640 650
QRAKNNTVAY APQDPWIMDG SIKENILMGL DLVPEFYERV VTACGLNVDM
660 670 680 690 700
AQLRGGENTI VGDRGVQLSG GQRSRIALAR VFYRDADVLL LDDPLSAVDS
710 720 730 740 750
KVGRGLVYAI SKLAVDRGKC VILVTHQHQY IGDNRCVLMD GGRITCVGSY
760 770 780 790 800
QDCLHASNGK MTFKAQHPSA PDLEKLDKSK DEVKDTAPDN VKRGDEASDE
810 820 830 840 850
PAQDGVDDHK ELSKVGVVGR DTFLNYLQAM PGGIMTGWLM ILPKMLLFTA
860 870 880 890 900
TQGSVLGTVA FIGMWSEMSA ADQSSTQVIA IVVALVVIVI ILALARAFSS
910 920 930 940 950
FHLTVQASKN LHDAMTRAVL KARVSFFDTN PLGRILNRFS SDVGSNDDLL
960 970 980 990 1000
PNTLFDFLVI SFLVAGALLS AVVVLPVTLL VVPPLCWYFV LVRSTFVTTS
1010 1020 1030 1040 1050
RELKRLEGLS RSPIFAMLSE SLTGISTIRP NGAIDYFQKK FFAAHDAHGR
1060 1070 1080 1090 1100
SFFAFIACSR WLGFRYAMDS LMFVFLAVAS FTAVLVQQNE WFSIDPGILV
1110 1120 1130 1140 1150
SYGLYHNALE VPCPHVICLK KGLAISMLVQ LSGLFQWCIR QSAEVVNQFV
1160 1170 1180 1190 1200
AVERYGGVRL LLATKVDLPS EAALSNERDR EVKDWPSKGE IDVSDLCVRY
1210 1220 1230 1240 1250
RAGLPLSLRG VTFKVEGGGT VGVVGRTGGG KSTLVQSLLR LLEADSGLIT
1260 1270 1280 1290 1300
IDGVDIKSLG LHKLRNAISV IPQQPMLYGG VSIRDNLDPF QRFSTERINE
1310 1320 1330 1340 1350
ALDDVHMSDA VQALHDGLDT IVAEGGTNFS VGQRQLLCLA RAILRRNRIL
1360 1370 1380 1390 1400
VLDEPTANVD SRTDTLLQEA VAKSFHDATI LAVAHRLDTI IEYSRILVLG
1410 1420 1430 1440 1450
GGRVLEYGSP RELVSRRGEF YSMIQETGEE SAANLIARAK GSNGLTTTSL
1460 1470 1480 1490 1500
GGIQWHSTLN DNATLNDNDA VGILPPSEVR TGHRIEFILY YPVPGACLSF
1510 1520 1530 1540 1550
KEEYRRQGFV PPLAGVAGGA IKQMDALWTG RELTCKLSER REAAARSAPR
1560 1570 1580 1590 1600
GSPQVAASKV SGRVPFEGAM CLPSEHKVSA EGLFISMIGW SLSMPSQIFL
1610 1620 1630
HKQLLVRENN EHSSSPRSSA LSSKLWMGNF DEKELAVI
Length:1,638
Mass (Da):179,874
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4424D3CE468C50D1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AGNL01015215 Genomic DNA Translation: EJK66189.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EJK66189; EJK66189; THAOC_12905

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGNL01015215 Genomic DNA Translation: EJK66189.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEJK66189; EJK66189; THAOC_12905

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK0SML4_THAOC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K0SML4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: January 16, 2019
This is version 32 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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