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Entry version 32 (07 Oct 2020)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Type VI secretion system protein ImpL

Gene

BUPH_06113

Organism
Paraburkholderia phenoliruptrix BR3459a
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Type VI secretion system protein ImpLImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BUPH_06113Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiParaburkholderia phenoliruptrix BR3459aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1229205 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeParaburkholderia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000010105 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Transmembranei443 – 462HelicalSequence analysisAdd BLAST20

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
1229205.BUPH_06113

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini191 – 445IcmF-related_NInterPro annotationAdd BLAST255
Domaini495 – 847IcmF-relatedInterPro annotationAdd BLAST353
Domaini1118 – 1220IcmF_CInterPro annotationAdd BLAST103

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1262 – 1291DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili467 – 501Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG3523, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003353_4_0_4

KEGG Orthology (KO)

More...
KOi
K11891

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009612, IcmF-related
IPR025743, IcmF-related_N_dom
IPR010623, IcmF_C
IPR027417, P-loop_NTPase
IPR017731, TssM1-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06761, IcmF-related, 1 hit
PF14331, IcmF-related_N, 1 hit
PF06744, IcmF_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03348, VI_IcmF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K0DXI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRFLNVLTH PRTLSIIGLL ALAAVLFVGA DTLQIDLMWP AIALAALVAL
60 70 80 90 100
WLLVWVVRRL RARRANDKLG EMLEQQAEKQ SADAGPAPTP ARQAELDVLR
110 120 130 140 150
TRLVDAVKTI KTSKIGQLSG GSALYELPWY IVIGNPAAGK SSAVLNSGLQ
160 170 180 190 200
FPFADKNNAV IHGIGGTRNC DWFFTTEGIL LDTAGRYSVH EEDRTEWLGF
210 220 230 240 250
LGLLKKFRPK APINGIIVTA SIAELTSSKP EFAINLAKNL RQRVQELTEK
260 270 280 290 300
LEVFAPVYVM FTKADLITGF TEFFSGSDRH EYDRVWGATL PYEPDEKRDV
310 320 330 340 350
VGLFDEHFEE LYDGLKEISV AQMSINRGNK LSPGQLSFPL EFSTIKPALR
360 370 380 390 400
AFLATLFETN PFQYKPIFRG FYFTSALQEG ETSSAAATRI ANRFGLSAES
410 420 430 440 450
MPKPHSAFSK NGFFLRDLFS KVIFADRQTV RQFASPAKTR MRYSTFFGFV
460 470 480 490 500
AVLALALGGW TWSTVNNQQL AENVKADLDN VVRLQQNRND LQSRLQAMDV
510 520 530 540 550
LEDRIDQLEQ FRRDKPLAVS LGLYQGDRLE QRLLTEYYNG VRQILLDPVS
560 570 580 590 600
QNLASFLKDV NAHPDQLAPL NRTPDAAAIP VSTHSAMTAS GQGGLYSDAS
610 620 630 640 650
PTNVEDAYNA LKTYLMLSDK RHVETAHLTD QVARFWRGWL ETNRGNMPRD
660 670 680 690 700
EMIRSAERMI TFYLSRVSDD DWPMIDQNLG LVDQTRENLR RVVRGMPARQ
710 720 730 740 750
RVYEEIKARA STRFAPMTIA RIVGENNTAL VAGSYAIPGT FTREAWFQYV
760 770 780 790 800
QPAIREAATK ELQAKDWVLN TSAHDDLTLE GSPEQIQKAL VMMYKTEYAM
810 820 830 840 850
HWQKFMQGIA VQSFGSFGQA VDAMNRLGDP QDSPIRKVLE TAYDQTSWDN
860 870 880 890 900
PSLFNASLKR AQSGVTSWFK QWFSRAPTGQ LNANIDINGN PVEMPMGPIG
910 920 930 940 950
QEFSALGRIV QTGDNGSMLK GYMDTLSKVR TRFNVIKNQG DPGPGARQLM
960 970 980 990 1000
QQTLDGSGSE LADSLKYVDE QMLTGLTDSQ RKALRPLLVR PLMAAYAVVI
1010 1020 1030 1040 1050
QPASVEVNKV WNAQVYQTFQ NSLASKYPFA GDAKVEAGAG EIAQVFGPDG
1060 1070 1080 1090 1100
SIAKFVGTTL GPLAVRRGDT LTARTWGDMG LALTPDFTNG FARWVAPLAG
1110 1120 1130 1140 1150
GAAGASAGQS SAEPQTVFQI LPQPSSGTTE YTLAIDGQQM RYRNTPPQWT
1160 1170 1180 1190 1200
NFVWPNPSGS PGATLSATTF DGRTLQLVNE PGRYGLEKLI NSAQRKRRPD
1210 1220 1230 1240 1250
GTFDLSWTQG NVTVAVSMRI ISTSQASGGS SDAPQQQSLR GLRLPSSVAD
1260 1270 1280 1290
VSAAANSVAA TNTASSAAPV ASAVPAARPA TAAVSNTGGA Q
Length:1,291
Mass (Da):141,899
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i20DAE9A484913494
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP003864 Genomic DNA Translation: AFT89640.1

NCBI Reference Sequences

More...
RefSeqi
WP_014973299.1, NC_018672.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AFT89640; AFT89640; BUPH_06113

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bpx:BUPH_06113

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1229205.11.peg.6257

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003864 Genomic DNA Translation: AFT89640.1
RefSeqiWP_014973299.1, NC_018672.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi1229205.BUPH_06113

Genome annotation databases

EnsemblBacteriaiAFT89640; AFT89640; BUPH_06113
KEGGibpx:BUPH_06113
PATRICifig|1229205.11.peg.6257

Phylogenomic databases

eggNOGiCOG3523, Bacteria
HOGENOMiCLU_003353_4_0_4
KOiK11891

Family and domain databases

InterProiView protein in InterPro
IPR009612, IcmF-related
IPR025743, IcmF-related_N_dom
IPR010623, IcmF_C
IPR027417, P-loop_NTPase
IPR017731, TssM1-like
PfamiView protein in Pfam
PF06761, IcmF-related, 1 hit
PF14331, IcmF-related_N, 1 hit
PF06744, IcmF_C, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR03348, VI_IcmF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK0DXI1_9BURK
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K0DXI1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: October 7, 2020
This is version 32 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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