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Entry version 38 (31 Jul 2019)
Sequence version 1 (28 Nov 2012)
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Protein
Submitted name:

Uncharacterized protein

Gene

CNAG_04327

Organism
Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CNAG_04327Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri235443 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus neoformans species complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000010091 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:CNAG_04327

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
J9VS18

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini174 – 263KHInterPro annotationAdd BLAST90
Domaini360 – 425KHInterPro annotationAdd BLAST66
Domaini515 – 595KHInterPro annotationAdd BLAST81
Domaini596 – 671KHInterPro annotationAdd BLAST76
Domaini680 – 757KHInterPro annotationAdd BLAST78
Domaini761 – 835KHInterPro annotationAdd BLAST75
Domaini840 – 910KHInterPro annotationAdd BLAST71
Domaini914 – 992KHInterPro annotationAdd BLAST79
Domaini996 – 1081KHInterPro annotationAdd BLAST86
Domaini1217 – 1282KHInterPro annotationAdd BLAST66

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 65DisorderedSequence analysisAdd BLAST65
Regioni209 – 249DisorderedSequence analysisAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili587 – 607Sequence analysisAdd BLAST21
Coiled coili742 – 765Sequence analysisAdd BLAST24
Coiled coili1192 – 1216Sequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1370.10, 10 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00013 KH_1, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00322 KH, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54791 SSF54791, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

J9VS18-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFSAADLQK QHQELEGAPD PFPALAHAPV PVAKKVQSAP APLDTSSEDA
60 70 80 90 100
FPSLAAPSAP SSKGNVKPAI SMWASKSSAV KTGVAKPMAP GGLGRTGTPT
110 120 130 140 150
AGSHPFAETF SIPANELVQG KAASDVVKKV QDQTGAIVES STQMRTGLKT
160 170 180 190 200
FHVKAADQKK LAQAKRMIEG GLRKPVTVQV EVPITTLGTI IGPKGATLKG
210 220 230 240 250
ITDATGAKVD VPRRETLPSY TPKDNGSDAG SDDEDGEPQV SITISGPATG
260 270 280 290 300
CTDAKDRILS LISHKMSQTS TSIKTIPSAF YTIISTQVSE LEQGPGEGKV
310 320 330 340 350
TVKVPIPAVW KALERQAQAD AEGEKVVVDG EAPIKVKGDR ENVKAVIDEI
360 370 380 390 400
TKSYDSLVQS FNLKKVSIPK RQHRFLIGSA AEDILAQTGC VVELPPVDDP
410 420 430 440 450
SDRVVIRGPP AKLVAAQSLV FEKANAVSVE PLDLVSVFRR TTSDPVTHAT
460 470 480 490 500
NILRYLRASK LKDVSSAYPN VQIFPPFPST VANTGTVIIE IVSEDGEEVS
510 520 530 540 550
KVVDEITNLA KGILPSAVSI VQVDHLAHSL LVGKKGTRIA QFEKTHNVTV
560 570 580 590 600
VFPPASEESS NVLLVYTGPA DKDVKLEEVF EGASKDLTEL AKEVADIKTE
610 620 630 640 650
ILEVEKKWHK YIIGQNGSVL NAIIGEDALV SVKVGTSTTK FPSTGSEDSV
660 670 680 690 700
TIRGPRNEVD RVTKQIKQVV EDAKNDDIVN GYTVKFDVEK KYVPHLVGQA
710 720 730 740 750
GAAINKLRET LGVKVNFEDA PEKETKKGAK KVLVNCSIVG RKEPVEEAKK
760 770 780 790 800
RLIAQIEKLE DETTEVLSIK RAIQPALIGA GGKYAIRLEE KYGVKLSFPR
810 820 830 840 850
DSKDKESGAN PDQVTIRGGR KGVAAVKAEL LEAAAFETES RQEATFKVPS
860 870 880 890 900
KAVAQIVGKG GATINAIKND TGAQIDIERE GGEDKQTTIT VRGDKQAIAA
910 920 930 940 950
AKEAVLNVVK EVGDEITVEL TIEQKYHRNL IGQGGQNLRD LIASAGGPSE
960 970 980 990 1000
GYKQAGLVTF PKNGDESTDK VRLRGDSKVV KKIQTELEKQ VAVLKDTIVI
1010 1020 1030 1040 1050
GVVVPATQHA TKIGRGGMAL QDLQRKTGAV IHFPGSRQYS SIGEIENQDD
1060 1070 1080 1090 1100
LEGVSEGDIV KVIGTKEVTQ KAAELLQVTS ERGQRSDSRQ GRATPDLVSC
1110 1120 1130 1140 1150
PVSIPNKYYH AIAETPNLIR QIRAVGGYLN IPQPAPAKPS LKRPEPTSGD
1160 1170 1180 1190 1200
DLAAKTARID LDGDETVPDV QGEWSLVKNF EGADDEKSEW VVRAKEEDLE
1210 1220 1230 1240 1250
RAVKVLEQAL EKARKATHVG YLTGLPRSAF PRIIGSKGAT ISRMRLETGA
1260 1270 1280
DIQVGKEDDL ITIIGDEESV LQAKDAILSI VSRPSRERY
Length:1,289
Mass (Da):138,079
Last modified:November 28, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1C0739699EFE26DE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP003828 Genomic DNA Translation: AFR97058.1

NCBI Reference Sequences

More...
RefSeqi
XP_012051735.1, XM_012196345.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
AFR97058; AFR97058; CNAG_04327

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23887762

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003828 Genomic DNA Translation: AFR97058.1
RefSeqiXP_012051735.1, XM_012196345.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

PTM databases

SwissPalmiJ9VS18

Genome annotation databases

EnsemblFungiiAFR97058; AFR97058; CNAG_04327
GeneIDi23887762

Organism-specific databases

EuPathDBiFungiDB:CNAG_04327

Family and domain databases

Gene3Di3.30.1370.10, 10 hits
InterProiView protein in InterPro
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
PfamiView protein in Pfam
PF00013 KH_1, 8 hits
SMARTiView protein in SMART
SM00322 KH, 10 hits
SUPFAMiSSF54791 SSF54791, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJ9VS18_CRYNH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: J9VS18
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2012
Last sequence update: November 28, 2012
Last modified: July 31, 2019
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health

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