UniProtKB - J9P7E1 (J9P7E1_CANLF)
Protein
Band 4.1
Gene
EPB41
Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Functioni
GO - Molecular functioni
- actin binding Source: InterPro
- calmodulin binding Source: UniProtKB-KW
- structural molecule activity Source: InterPro
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- cell division Source: UniProtKB-KW
- cortical actin cytoskeleton organization Source: InterPro
Keywordsi
Molecular function | Calmodulin-bindingARBA annotation |
Biological process | Cell cycle, Cell division, MitosisARBA annotation, TransportARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Band 4.1ARBA annotationAlternative name(s): Erythrocyte membrane protein band 4.1ARBA annotation Protein 4.1ARBA annotation |
Gene namesi | Name:EPB41Imported |
Organismi | Canis lupus familiaris (Dog) (Canis familiaris)Imported |
Taxonomic identifieri | 9615 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Canidae › Canis › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:40392, EPB41 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Other locations
- cell cortex ARBA annotation
Cytoskeleton
- cytoskeleton Source: InterPro
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- cell cortex Source: UniProtKB-SubCell
Expressioni
Gene expression databases
Bgeei | ENSCAFG00000011677, Expressed in thymus and 51 other tissues |
Interactioni
GO - Molecular functioni
- actin binding Source: InterPro
- calmodulin binding Source: UniProtKB-KW
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 211 – 492 | FERMInterPro annotationAdd BLAST | 282 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 124 | DisorderedSequence analysisAdd BLAST | 124 | |
Regioni | 152 – 203 | DisorderedSequence analysisAdd BLAST | 52 | |
Regioni | 518 – 613 | DisorderedSequence analysisAdd BLAST | 96 | |
Regioni | 682 – 719 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 816 – 843 | DisorderedSequence analysisAdd BLAST | 28 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 638 – 658 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 41 | PolarSequence analysisAdd BLAST | 41 | |
Compositional biasi | 42 – 78 | PolyampholyteSequence analysisAdd BLAST | 37 | |
Compositional biasi | 92 – 123 | PolyampholyteSequence analysisAdd BLAST | 32 | |
Compositional biasi | 158 – 203 | PolyampholyteSequence analysisAdd BLAST | 46 | |
Compositional biasi | 586 – 613 | PolyampholyteSequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000157833 |
TreeFami | TF351626 |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR008379, Band_4.1_C IPR019749, Band_41_domain IPR021187, Band_41_protein_chordates IPR000798, Ez/rad/moesin-like IPR014847, FERM-adjacent IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR019747, FERM_CS IPR000299, FERM_domain IPR018979, FERM_N IPR018980, FERM_PH-like_C IPR011993, PH-like_dom_sf IPR007477, SAB_dom IPR029071, Ubiquitin-like_domsf |
PANTHERi | PTHR23280:SF12, PTHR23280:SF12, 2 hits |
Pfami | View protein in Pfam PF05902, 4_1_CTD, 1 hit PF08736, FA, 1 hit PF09380, FERM_C, 1 hit PF00373, FERM_M, 1 hit PF09379, FERM_N, 1 hit PF04382, SAB, 1 hit |
PRINTSi | PR00935, BAND41 PR00661, ERMFAMILY |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM01195, FA, 1 hit SM01196, FERM_C, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660, FERM_1, 1 hit PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
J9P7E1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTEKSLVAE AENSQHQQQK EEGEGVTNSG QQETQLEELS QEAAEGDNHC
60 70 80 90 100
EQKLKTSNGD TPTHEDLTKN KERTSENRGL SRLFSSFLKR PKSQVSEEEG
110 120 130 140 150
KDVESAKEKC EGGQKEIEFG TSLDEEIILK APIAAPEPEL KTDPSLDLHS
160 170 180 190 200
LSSAETQPAQ EEHREDPDFE TKEGGGLEEC SKIEVKEESP ESKAERELKA
210 220 230 240 250
SQKSIRRHRN MHCKVSLLDD TVYECVVEKH AKGQDLLKRV CEHLNLLEED
260 270 280 290 300
YFGLAIWDNG ASKTWLDSAK EIKKQVRGVP WNFTFNVKFY PPDPAQLTED
310 320 330 340 350
ITRYYLCLQL RQDIVSGRLP CSFATLALLG SYTIQSELGD YDPELHGAEY
360 370 380 390 400
VSDFKLAPNQ TKELEEKVME LHKSYRSMTP AQADLEFLEN AKKLSMYGVD
410 420 430 440 450
LHKAKDLEGV DIILGVCSSG LLVYKDKLRI NRFPWPKVLK ISYKRSSFFI
460 470 480 490 500
KIRPGEQEQY ESTIGFKLPS YRAAKKLWKV CVEHHTFFRL TSTDTLPKSK
510 520 530 540 550
FLALGSKFRY SGRTQAQTRQ ASALIDRPAP HFERTASKRA SRSLDGAAAV
560 570 580 590 600
DSDRSPRPTS APAIAQSQDA EGTVPGAPVK KTVVSKAQKE TVKDEEKKEE
610 620 630 640 650
GPPDQAEPEP TEVWKKKRER LDGENIYIRH SNLMLEDLDK SQEEIKKHHA
660 670 680 690 700
SISELKKNFM ESVPEPRPSE WDKRLSTHSP FRTLNINGQL PTGEGLKMAK
710 720 730 740 750
NSPSTIEPVS PSKTGEFLNA PPLVKTQTVT ISDTANSVKS EIPTKDVPIV
760 770 780 790 800
HTETKTITYE AAQTDDSNGD LDPGVLLTAQ TITSETTSST TTTQITKTVK
810 820 830 840
GGISETRIEK RIVITGDADI DHDQELSYPK SLPVSHPREK PAK
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F4C3L2 | A0A5F4C3L2_CANLF | Band 4.1 | EPB41 | 1,039 | Annotation score: | ||
A0A5F4C9F6 | A0A5F4C9F6_CANLF | Band 4.1 | EPB41 | 1,014 | Annotation score: | ||
G1K2A4 | G1K2A4_CANLF | Band 4.1 | EPB41 | 884 | Annotation score: | ||
A0A5S6CHK8 | A0A5S6CHK8_CANLF | Band 4.1 | EPB41 | 881 | Annotation score: | ||
A0A5F4D0P1 | A0A5F4D0P1_CANLF | Band 4.1 | EPB41 | 993 | Annotation score: | ||
E2RGX9 | E2RGX9_CANLF | Band 4.1 | EPB41 | 960 | Annotation score: | ||
A0A5F4BVK3 | A0A5F4BVK3_CANLF | Band 4.1 | EPB41 | 1,025 | Annotation score: | ||
A0A5F4CU29 | A0A5F4CU29_CANLF | Band 4.1 | EPB41 | 1,018 | Annotation score: | ||
A0A5F4DDM2 | A0A5F4DDM2_CANLF | Band 4.1 | EPB41 | 979 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEX03001697 Genomic DNA No translation available. AAEX03001698 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSCAFT00000048787; ENSCAFP00000041578; ENSCAFG00000011677 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEX03001697 Genomic DNA No translation available. AAEX03001698 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | J9P7E1 |
Genome annotation databases
Ensembli | ENSCAFT00000048787; ENSCAFP00000041578; ENSCAFG00000011677 |
Organism-specific databases
VGNCi | VGNC:40392, EPB41 |
Phylogenomic databases
GeneTreei | ENSGT00940000157833 |
TreeFami | TF351626 |
Gene expression databases
Bgeei | ENSCAFG00000011677, Expressed in thymus and 51 other tissues |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR008379, Band_4.1_C IPR019749, Band_41_domain IPR021187, Band_41_protein_chordates IPR000798, Ez/rad/moesin-like IPR014847, FERM-adjacent IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR019747, FERM_CS IPR000299, FERM_domain IPR018979, FERM_N IPR018980, FERM_PH-like_C IPR011993, PH-like_dom_sf IPR007477, SAB_dom IPR029071, Ubiquitin-like_domsf |
PANTHERi | PTHR23280:SF12, PTHR23280:SF12, 2 hits |
Pfami | View protein in Pfam PF05902, 4_1_CTD, 1 hit PF08736, FA, 1 hit PF09380, FERM_C, 1 hit PF00373, FERM_M, 1 hit PF09379, FERM_N, 1 hit PF04382, SAB, 1 hit |
PRINTSi | PR00935, BAND41 PR00661, ERMFAMILY |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM01195, FA, 1 hit SM01196, FERM_C, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660, FERM_1, 1 hit PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | J9P7E1_CANLF | |
Accessioni | J9P7E1Primary (citable) accession number: J9P7E1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 31, 2012 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 59 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |