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UniProtKB - J9NZY8 (J9NZY8_CANLF)
Protein
Olfactory receptor
Gene
OR52E8C
Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Functioni
Putative odorant or sperm cell receptor.
ARBA annotationGO - Molecular functioni
- G protein-coupled receptor activity Source: UniProtKB-KW
- olfactory receptor activity Source: InterPro
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotationARBA annotation, Receptor, Transducer |
Biological process | OlfactionUniRule annotation, Sensory transduction |
Names & Taxonomyi
Protein namesi | Recommended name: Olfactory receptorUniRule annotation |
Gene namesi | Name:OR52E8CImported |
Organismi | Canis lupus familiaris (Dog) (Canis familiaris)Imported |
Taxonomic identifieri | 9615 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Canidae › Canis › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:96635, OR52E8C |
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 27 – 51 | HelicalUniRule annotationAdd BLAST | 25 | |
Transmembranei | 63 – 91 | HelicalUniRule annotationAdd BLAST | 29 | |
Transmembranei | 103 – 122 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 142 – 166 | HelicalUniRule annotationAdd BLAST | 25 | |
Transmembranei | 198 – 220 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 241 – 261 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 273 – 295 | HelicalUniRule annotationAdd BLAST | 23 |
Keywords - Cellular componenti
Cell membraneUniRule annotation, MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 293 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 251 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | ENOG502RYU0, Eukaryota |
GeneTreei | ENSGT01040000240377 |
HOGENOMi | CLU_012526_0_0_1 |
InParanoidi | J9NZY8 |
OMAi | RMSMPND |
TreeFami | TF343679 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR000725, Olfact_rcpt |
Pfami | View protein in Pfam PF13853, 7tm_4, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00245, OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
J9NZY8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATPNDTQFH PSSFLLLGIP ELEDVQFWIG FPFFFVYLVA LLGNAAVLFV
60 70 80 90 100
IQTEHSLHEP MYYFLAMLDS IDLGLSTATI PKMLGIFWFS LRDISFESCL
110 120 130 140 150
SQMFFIHFFT VMESIVLVAM AFDRYIAICK PLRYTMILTS KIIIIIAGIA
160 170 180 190 200
ILRSLCMVIP LVFLLLRLPF CGHHIIPHTY CEHMGIARLA CASIKVNILF
210 220 230 240 250
GLGNISLLLL DVLLIILSYV RILHAVFCLP SREARLKALN TCGSHIGVIL
260 270 280 290 300
AFFTPAFFSF LTHRFGHNIP QYIHIFLANL YVVVPPAFNP VIYGVRTKQI
310
RERVLRVFFR TES
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEX03012850 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSCAFT00000047232; ENSCAFP00000038859; ENSCAFG00000031086 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAEX03012850 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9612.ENSCAFP00000038859 |
Protein family/group databases
GPCRDBi | Search... |
Proteomic databases
PaxDbi | J9NZY8 |
Genome annotation databases
Ensembli | ENSCAFT00000047232; ENSCAFP00000038859; ENSCAFG00000031086 |
Organism-specific databases
VGNCi | VGNC:96635, OR52E8C |
Phylogenomic databases
eggNOGi | ENOG502RYU0, Eukaryota |
GeneTreei | ENSGT01040000240377 |
HOGENOMi | CLU_012526_0_0_1 |
InParanoidi | J9NZY8 |
OMAi | RMSMPND |
TreeFami | TF343679 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR000725, Olfact_rcpt |
Pfami | View protein in Pfam PF13853, 7tm_4, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00245, OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | J9NZY8_CANLF | |
Accessioni | J9NZY8Primary (citable) accession number: J9NZY8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 31, 2012 |
Last sequence update: | December 11, 2019 | |
Last modified: | January 19, 2022 | |
This is version 58 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |