Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-202733 Cell surface interactions at the vascular wall
R-CFA-5690714 CD22 mediated BCR regulation
R-CFA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei596 – 617HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500382535026 – 620Sequence analysisAdd BLAST595

Proteomic databases

PaxDbiJ9NVC6
PRIDEiJ9NVC6

Expressioni

Gene expression databases

BgeeiENSCAFG00000030258 Expressed in 3 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000037118

Structurei

3D structure databases

ProteinModelPortaliJ9NVC6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 121Ig-likeInterPro annotationAdd BLAST97
Domaini149 – 249Ig-likeInterPro annotationAdd BLAST101
Domaini256 – 357Ig-likeInterPro annotationAdd BLAST102
Domaini365 – 465Ig-likeInterPro annotationAdd BLAST101
Domaini475 – 576Ig-likeInterPro annotationAdd BLAST102

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHN5 Eukaryota
ENOG4111XUQ LUCA
GeneTreeiENSGT00530000063726
InParanoidiJ9NVC6
OrthoDBiEOG091G0AG6

Family and domain databases

Gene3Di2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07654 C1-set, 4 hits
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 2 hits
SM00407 IGc1, 4 hits
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 5 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 5 hits
PS00290 IG_MHC, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

J9NVC6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESVLSWVFL VAILKGCLVS AGVQGEVQLV ESGGDLVKPG GSLRLSCVAS
60 70 80 90 100
GFTFSSNYMS WIRQAPGKGL QWVSQISSDG SSTSYADAVK GRFTISRDNA
110 120 130 140 150
KNTLYLQMNS LRDEDTAVYY CARDTNHNCF DYWGQGTLVT VSSESPSPPN
160 170 180 190 200
LFPLITCENS LSDETLVAMG CLARDFLPGS ITFSWKYENL SAINNQDIKT
210 220 230 240 250
FPSVLREGKY VATSQVFLPS VDIIQGSDEY ITCNVKHSNG DKSVNVPITG
260 270 280 290 300
PVPTSPNVTV FIPPRDAFSG NGQRKSQLIC QAAGFSPKQI SVSWFRDGKQ
310 320 330 340 350
IESGFNTGKA EAEEKEHGPV TYSILSMLTI TESAWLSQSV FTCHVEHNGI
360 370 380 390 400
IFQKNVSSMC TSNTPVGISI FTIPPSFASI FNTKSAKLSC LVTDLATYDS
410 420 430 440 450
LTISWTRQNG EALKTHTNIS ESHPNNTFSA MGEATVCVEE WESGEQFTCT
460 470 480 490 500
VTHTDLPSPL KKTISRPKDV NKHMPSVYVL PPSREQLSLR ESASLTCLVK
510 520 530 540 550
GFSPPDVFVQ WLQKGQPVPP DSYVTSAPMP EPQAPGLYFV HSILTVSEED
560 570 580 590 600
WNAGETYTCV VGHEALPHVV TERSVDKSTG GEVSAEEEGF ENLNTMASTF
610 620
IVLFLLSVFY STTVTLFKVV
Length:620
Mass (Da):67,643
Last modified:October 31, 2012 - v1
Checksum:i86D7AEDD053D284A
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E2RE31E2RE31_CANLF
Uncharacterized protein
492Annotation score:
J9NYW7J9NYW7_CANLF
Uncharacterized protein
403Annotation score:
F1PKI5F1PKI5_CANLF
Uncharacterized protein
121Annotation score:
E2RCC8E2RCC8_CANLF
Uncharacterized protein
473Annotation score:
J9P182J9P182_CANLF
Uncharacterized protein
118Annotation score:
J9NWX7J9NWX7_CANLF
Uncharacterized protein
140Annotation score:
J9NSV4J9NSV4_CANLF
Uncharacterized protein
116Annotation score:
J9P482J9P482_CANLF
Uncharacterized protein
116Annotation score:
J9P3B7J9P3B7_CANLF
Uncharacterized protein
141Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03006126 Genomic DNA No translation available.
AAEX03006127 Genomic DNA No translation available.
AAEX03006128 Genomic DNA No translation available.
AAEX03006129 Genomic DNA No translation available.
AAEX03006130 Genomic DNA No translation available.
AAEX03006131 Genomic DNA No translation available.
AAEX03006132 Genomic DNA No translation available.
AAEX03006133 Genomic DNA No translation available.
AAEX03006134 Genomic DNA No translation available.
AAEX03006135 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000048072; ENSCAFP00000037118; ENSCAFG00000030258

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03006126 Genomic DNA No translation available.
AAEX03006127 Genomic DNA No translation available.
AAEX03006128 Genomic DNA No translation available.
AAEX03006129 Genomic DNA No translation available.
AAEX03006130 Genomic DNA No translation available.
AAEX03006131 Genomic DNA No translation available.
AAEX03006132 Genomic DNA No translation available.
AAEX03006133 Genomic DNA No translation available.
AAEX03006134 Genomic DNA No translation available.
AAEX03006135 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ9NVC6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000037118

Proteomic databases

PaxDbiJ9NVC6
PRIDEiJ9NVC6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000048072; ENSCAFP00000037118; ENSCAFG00000030258

Phylogenomic databases

eggNOGiENOG410IHN5 Eukaryota
ENOG4111XUQ LUCA
GeneTreeiENSGT00530000063726
InParanoidiJ9NVC6
OrthoDBiEOG091G0AG6

Enzyme and pathway databases

ReactomeiR-CFA-202733 Cell surface interactions at the vascular wall
R-CFA-5690714 CD22 mediated BCR regulation
R-CFA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Gene expression databases

BgeeiENSCAFG00000030258 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

Gene3Di2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07654 C1-set, 4 hits
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 2 hits
SM00407 IGc1, 4 hits
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 5 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 5 hits
PS00290 IG_MHC, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiJ9NVC6_CANLF
AccessioniPrimary (citable) accession number: J9NVC6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: September 12, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again