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Entry version 29 (11 Dec 2019)
Sequence version 2 (14 May 2014)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Acyrthosiphon pisum (Pea aphid)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcyrthosiphon pisum (Pea aphid)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7029 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeMacrosiphiniAcyrthosiphon
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007819 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini577 – 765Integrase catalyticInterPro annotationAdd BLAST189
Domaini2367 – 2555Integrase catalyticInterPro annotationAdd BLAST189

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1269 – 1288DisorderedSequence analysisAdd BLAST20

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
J9K0A1

Database of Orthologous Groups

More...
OrthoDBi
222689at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.70.10, 1 hit
3.30.420.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001969 Aspartic_peptidase_AS
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR008737 Peptidase_asp_put
IPR021109 Peptidase_aspartic_dom_sf
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 2 hits
PF05380 Peptidase_A17, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50630 SSF50630, 1 hit
SSF53098 SSF53098, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00141 ASP_PROTEASE, 1 hit
PS50994 INTEGRASE, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

J9K0A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESIALLSLV LRVLKDIADN ECNGFPEVQD GLRYQTYVND ICLGADTEEL
60 70 80 90 100
LSKLQSELKA VLGRSALELK KWSSNSRRVL LDVAAADRVS DVINFDDKEG
110 120 130 140 150
GTIKVLGLRW EPVKDVFGFD VRPVTKVITK RSVLSTIATI FDPIGFLAPV
160 170 180 190 200
IFHAKHIMQL IWKAELGWDD PLPDDLIRTW KLLLNDLPVL SKVEIPRFLS
210 220 230 240 250
TTITSDVQLC GFCDASEHGY AAVAYLRVTS SPGLVTTHLL GSKTKMSPMK
260 270 280 290 300
TSTIPRLELC AAVLLARWLT RLLTIFGDRL CFNGIFAWSD SQIVMSWLVN
310 320 330 340 350
PHTCFKVFVS NRVHLVRQLV PSCRWGYVRS SENPADCASR GLLPSDLVKH
360 370 380 390 400
LLYWSGPAFL KDNVDTWDMS VSAVPIEQLS EAKVTSLSVQ IDPEGEWFSR
410 420 430 440 450
FSSYHNMVRV VAWMRRFVGR ARKQKYASEF LNREELDDSL IILVKQSQTC
460 470 480 490 500
WLSKLHVDLA RGRPAQRLLA GLRPFIDTRG VICVGGRLAR SDLTSAEKQP
510 520 530 540 550
ILLARDSHLS VLLARHWHLV TCHSGPRVIT SLITRQFWII SVRAVIRRVI
560 570 580 590 600
GQCTICVRTL AQSPHPVIAD LPSSRVQMCR PFTRVGIDYA GPLSMRECRL
610 620 630 640 650
RKARQYKIYV AVFVCMSTKA VHLEVVSELS TNAFLAAFDR FVARRGLPHD
660 670 680 690 700
IFSDCGTNFV GAAKYLRALV NDPTIRHVLT SHVSCVWHFN PPSAPHFGGL
710 720 730 740 750
WEAAVRSFKT LLTRLVGIHT LSWEEMTTVL CRIEAVLNSR PLTPMSSSPM
760 770 780 790 800
DVDYLTPGHF LIGQPLLAVP DAPIPESCTR VVNRWKLLHQ CHQSFWRRWS
810 820 830 840 850
TEYLCSLQVR AKWTADVPNL QCGDMVVIKD SSPPMSWRLG RIIDVTPGND
860 870 880 890 900
GVVRVVKVNT ATGELTRPVV KLVKLPMDHY RDGVQPRATR FQPKTQRGDI
910 920 930 940 950
VLSGAATYLL IIIILGCVLR ILLPVGLGRR RRVDSNTTHW LHTLHAVRMP
960 970 980 990 1000
GSEKEAVERE LRVLQRAKTI AMLNRESTLN RMRAIADVAS RLKEEPELKP
1010 1020 1030 1040 1050
KLLTAARDLD SLWDTFMQHN EAVLNALLDL DLASEYSTTL ETEVRTLYFD
1060 1070 1080 1090 1100
ARAIVEEFAP LPIERALSHG TGHLSGSRHS LLSGRPSRRS RLPEIPLPSF
1110 1120 1130 1140 1150
SGELCGWPAF RDRFTDLVVL DEELTDSDRF YYLLGCLRGD ALSAISSISV
1160 1170 1180 1190 1200
SDGTYDLAWA TLVERFDKPR QLASLIIDKL MSAPIQSQES LSGLKEFLAL
1210 1220 1230 1240 1250
FSDQVAMLHT LRIPNLGEFI LFSLASRCLP YSTRKDFEAA NKQNFPSILD
1260 1270 1280 1290 1300
MVGYIKDRVS LLEAVNFSKG SSGAPPTQDR AKSVPPHSAG WKPKVVMIAS
1310 1320 1330 1340 1350
KSIGTAPPKC LFCSGEHVTT SCNAFTKMSV NDRVTAARDK RLCFRCLIST
1360 1370 1380 1390 1400
HWSTKCRVSK PCSRCHGRHH TLLHKDNDAE AQPIASTSAC HVSSSKQPAA
1410 1420 1430 1440 1450
LLGTAVVHVR DRYGCMQPVR ALIDSGSQIS IMSVPCVERL GLKCNKWTAP
1460 1470 1480 1490 1500
LTGVSGAAVL QVKGRVDCFI TPRYNDEHSI KLQAWVLPKI TSDMPAQPLP
1510 1520 1530 1540 1550
PQLVNKFSHL ALADPQFDCT APIELLLGAD VFSRVMDGKR VLLDPSLPAA
1560 1570 1580 1590 1600
YGSIFGWIVI GPVPEVAPDT YRSHIAVTLS VSLEDMVHRF WQVEEPDTAP
1610 1620 1630 1640 1650
ATFHDEGQCE AVYSAERYRD TNGRYVVPLP FKPLHRDELF PGSRQIAIRR
1660 1670 1680 1690 1700
FQNLERKLQA NEGLYAAYKE FMSDYESLGH MTIADEVGTY YIPHHPVFNA
1710 1720 1730 1740 1750
ARKIRVVFDA SAKASSHLSL NQCLHTGPKL QLDILEILTR FRLHKYVFTA
1760 1770 1780 1790 1800
DVCKMYRQIL MRPEYRCFQH IFWRSSPVEE LKEYQLNTVT YGVNYAPFLA
1810 1820 1830 1840 1850
LRILKDIADN ECNGFPEVQD GLRYQTYVDD ICLGADTEEL LSKLQSELKA
1860 1870 1880 1890 1900
VLGRSALELK KWSSNSRRVL LDVAAADRVS DVINFDDKEG GTIKVLGLRW
1910 1920 1930 1940 1950
EPVKDVFGFD VRPVTKVITK RSVLSTIATI FDPIGFLAPV IFHAKHIMQL
1960 1970 1980 1990 2000
IWKAELGWDD PLPDDLIRTW KLLLNDLPVL SKVEIPRFLS TTITSDVQLC
2010 2020 2030 2040 2050
GFCDASEHGY AAVAYLRVTS SPGLVTTHLL GSKTKMSPMK TSTIPRLELC
2060 2070 2080 2090 2100
AAVLLARWLT RLLTIFGDRL RFNGIFAWSD SQIVLSWLVN PHTCFKVFVS
2110 2120 2130 2140 2150
NRVHLVRQLV PSCRWGYVRS SENPADCASR GLLPSDLVKH LLYWSGPAFL
2160 2170 2180 2190 2200
KDNVDTWDMS VSAVPIEQLP EAKVTSLSVQ IDPEGEWFSR FSSYHNMVRV
2210 2220 2230 2240 2250
VAWMRRFVGR ARKQKYASEF LNREELDDSL IILVKQSQTC WLSKLHVDLA
2260 2270 2280 2290 2300
RGRPAQRSLA GLRPFIDTRG VICVGGRLAR SDLTSAEKQP ILLARDSHLS
2310 2320 2330 2340 2350
VLLARHWHLV TCHSGPRVIT SLITRQFWII SVRAVIRRVI GQCTICVRTL
2360 2370 2380 2390 2400
AQSPHPVMTD LPSSRVQMCR PFTRVGIDYA GPLSMRECRL RKARQYKIYV
2410 2420 2430 2440 2450
AVFVCMSTKA VHLEVVSELS TNAFLAAFDR FVARRGLPHD IFSDCGTNFV
2460 2470 2480 2490 2500
GAAKYLRALV NDPTIRHVLT SHVSCVWHFN PPSAPHFGGL WEAAVRSFKT
2510 2520 2530 2540 2550
LLTRLVGIHT LSWEEMTTVL CRIEAVLNSR PLTPMSSSPM DVDYLTPGHF
2560 2570 2580 2590 2600
LIGQPLLAVP DPPIPESCTR VVNRWKLLHQ CHQSFWRRWS TEYLCSLQVR
2610 2620 2630 2640 2650
AKWTADVPNL QCGDMVVIKD SSPPMSWRLG RIIDVTPGND GVARVVKVNT
2660
ATGELTRPVV KLVKLPMDQ
Length:2,669
Mass (Da):299,885
Last modified:May 14, 2014 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDE093F08D4F625A0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ABLF02067195 Genomic DNA No translation available.

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
ACYPI006154-RA; ACYPI006154-PA; ACYPI006154

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABLF02067195 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiACYPI006154-RA; ACYPI006154-PA; ACYPI006154

Phylogenomic databases

InParanoidiJ9K0A1
OrthoDBi222689at2759

Family and domain databases

Gene3Di2.40.70.10, 1 hit
3.30.420.10, 2 hits
InterProiView protein in InterPro
IPR001969 Aspartic_peptidase_AS
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR008737 Peptidase_asp_put
IPR021109 Peptidase_aspartic_dom_sf
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 2 hits
PF05380 Peptidase_A17, 2 hits
SUPFAMiSSF50630 SSF50630, 1 hit
SSF53098 SSF53098, 2 hits
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 1 hit
PS50994 INTEGRASE, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJ9K0A1_ACYPI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: J9K0A1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: May 14, 2014
Last modified: December 11, 2019
This is version 29 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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