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Entry version 47 (05 Jun 2019)
Sequence version 2 (14 May 2014)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Acyrthosiphon pisum (Pea aphid)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcyrthosiphon pisum (Pea aphid)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7029 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeMacrosiphiniAcyrthosiphon
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007819 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7029.ACYPI004504-PA

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini164 – 279PHInterPro annotationAdd BLAST116
Domaini644 – 819DHR-1InterPro annotationAdd BLAST176
Domaini1688 – 2125DHR-2InterPro annotationAdd BLAST438

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni281 – 301DisorderedSequence analysisAdd BLAST21
Regioni1395 – 1414DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1395 – 1412PolarSequence analysisAdd BLAST18

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DOCK family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1997 Eukaryota
ENOG410XNVY LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
J9JVV8

Database of Orthologous Groups

More...
OrthoDBi
20156at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
J9JVV8

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08697 C2_Dock-D, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037809 C2_Dock-D
IPR035892 C2_domain_sf
IPR027007 DHR-1_domain
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
IPR021816 DOCK_C/D_N
IPR011993 PH-like_dom_sf
IPR001849 PH_domain

The PANTHER Classification System

More...
PANTHERi
PTHR23317 PTHR23317, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06920 DHR-2, 1 hit
PF14429 DOCK-C2, 1 hit
PF11878 DUF3398, 1 hit
PF00169 PH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233 PH, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51650 DHR_1, 1 hit
PS51651 DHR_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

J9JVV8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGERKFTKGL GRPGMAAQLR ETVSQVVRDS SNNQKCFQVD PLDFEDYIAK
60 70 80 90 100
NHTVFQNDPQ RELLLYPSDD VSQVVLPRRY RTMDPSIPSN ADTTDCSLLT
110 120 130 140 150
KRCIESYSAN WHVIHYKYNA YSGSYIQFPS EVFKNDDFKE EIYEIDTDID
160 170 180 190 200
GLDKDWKTIK NDSALFKQGY LYKGPDGGGG ASERMFANLA GSKSFKRRFC
210 220 230 240 250
ILKQQVDGTY ILEVYKDDKK GDTKATIVMD LCDKVIRNSK KGRFCFELRM
260 270 280 290 300
VDTDKSYCLA SDTEPELMDW MTKLQLAIQH SNDKRDDKIP ENNKRCNMPI
310 320 330 340 350
IPPNDSFGTL KGLEHSVNPQ LMRYARETDS LNAHARQESR RRLFAVYPFL
360 370 380 390 400
QQVKDVLNQP ADSISEPYKE RFGQRVLIEC QALNFRLQIN NEENNDSINQ
410 420 430 440 450
VEPYFTTMAL FDIRSGKKIS EDFHFDINHD SMTNLVNHDN QIDGHKFIEI
460 470 480 490 500
SKNCKVTKNW LFKQKQAIMC ISKPHSDIYL VLRIDKVLQG GIVRVSEPYI
510 520 530 540 550
KATTNNKDTG LKVFKAVKNI CHRLGNYRMP FAWSARPLFR LYSCELDTSS
560 570 580 590 600
DFMTLYRQEL SKLGDDDMVK ILMEYRKPEK MNKCVIIPGH VQMKIQQLTS
610 620 630 640 650
TIPENILTTC WTAVKPFPIP PTRNHPIIEI AELYPDAQPH TAYINHMYVY
660 670 680 690 700
PLSLAFDTQK NIPRARNITC MVQLFDSDNI DSKPIKCIYG AHGQLLSSMC
710 720 730 740 750
TNVLYHSTNP IWYDEIKIRL PVHITPKHHL LFTFKHISVD GSRKKQSNIS
760 770 780 790 800
VETIVGYSWL PLIFKSKINM DAKCLPVSVG LPAGYLSVQP FGLGKGYCGP
810 820 830 840 850
EVCWIDGQKP LFSFKCHLLS SIYSSDNHMQ NLFAHAERLE HSKITTIIPP
860 870 880 890 900
ETETCKILKA SHAIDLISVI NFLPTLFNQL FNLLAFTSCT NIASNIIRLL
910 920 930 940 950
VHIVDSIQES GRCDTLNIYI KYVFTTPATN TPNNTVHDQL LAHLPNLLNP
960 970 980 990 1000
DNTDFLLINK FLVNSNFFFQ IVIKSMGQYL LTSNRIKMRR NERFSSEYQS
1010 1020 1030 1040 1050
RVHHMLIDVL LPYVTVKHKE MPSQVAKLNM AAAHFLKKCL TFMDRGFVFR
1060 1070 1080 1090 1100
LINVYISSLS TCDSTFVRSA KLLFMKIVIS HEHYVSFNLP VQNGQTPHGW
1110 1120 1130 1140 1150
SPHSQYYMSD EYCRHHFLTA ILLREVSNSF CSPYEYRHSA IACFRDLLAK
1160 1170 1180 1190 1200
HELDDRYQSK GQMARIASLY FPWLGVVIEN IGRLDYRKRT INHVVKRPIN
1210 1220 1230 1240 1250
LSSPRPNNLT NDIGPRMSLN LRDSTYFAAI ASHLTPSKKL ISLDHQQQEK
1260 1270 1280 1290 1300
LIKTDSSLSI NSCASNLSSP DRTNSLSMFS QETAVRRNSY ISESDVSNRN
1310 1320 1330 1340 1350
RHSRSISGTQ TFHITTDTSV NVVSKLEPTE VKDVLVCFLF ILKYSSQDQL
1360 1370 1380 1390 1400
ISWWRYCTEP DIVAFFKIIE LSLQEFQYMG RRHIVEETLA ANNRDNVQPT
1410 1420 1430 1440 1450
STTTTKKSMT LPARMQPPSE FNAETTANLN CQTQISQLTP PILSSNGTGS
1460 1470 1480 1490 1500
IGRVENSKKD TSTSDDNITF RVQSEANLTA EVGLVVLDAL SSYCVHFKDT
1510 1520 1530 1540 1550
LMAYNGENDI MESVFSTLVA FLCIPQSTLV CGHVFATLRS FINNFSCVLF
1560 1570 1580 1590 1600
KGTAHLVGKL CSQLLNGCNS RSSKVRQESC AALYLLMRSN FELSSSNITR
1610 1620 1630 1640 1650
VHLQTVIAVS QLLGDLTSAG LNNSRFQESL SLINSYANSD KVMKNTGFPM
1660 1670 1680 1690 1700
QVKDLTRRVR TVLMATARMK DLNHDPEMLA DLQHSLANSY ASTPELRLTW
1710 1720 1730 1740 1750
LQTMARNHDD NGDFSEAACC RLHIAALVAQ YRKLKGTQGW GAEAFGKISS
1760 1770 1780 1790 1800
NIARDETGLQ LDSGGGSVAA NDTLYGEQAL LDRLEACAVS LRRAELYECF
1810 1820 1830 1840 1850
GELYKLVIPV YEHRKDYHAL ADCYRTVGIA YDTAVSARQS GRRMLGRYYR
1860 1870 1880 1890 1900
VTLFGQAYFG DQHGVEFVYK EPKLTPLSDV SERLLCQYGD KFGRDNVRII
1910 1920 1930 1940 1950
MDSSTISISD LDVKFAYIQI THVVPYHGEK YMEIDNDSVS EFERNHDIDS
1960 1970 1980 1990 2000
FVFETPFTLG GGQSQSGPRE QWKRQTIIKT EYKFPYVKKR LRVCARREIE
2010 2020 2030 2040 2050
QCPIQVAIDE MCQRVRELRQ TVSAQPTDVK KLQLRLQGSV CVQVNAGPLA
2060 2070 2080 2090 2100
YARAFLEPQA VLELQADKVQ DLKDTFREFI SACFDALKLN RMLVSTDQIE
2110 2120 2130 2140 2150
YQDVMQENFL KMCRELSECI ESDSLWRDVL QSCTSPGNDS RTLFTAISGA

SQDSSNA
Length:2,157
Mass (Da):245,705
Last modified:May 14, 2014 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB60DA7393CE47B05
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ABLF02028408 Genomic DNA No translation available.
ABLF02028415 Genomic DNA No translation available.

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
ACYPI004504-RA; ACYPI004504-PA; ACYPI004504

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABLF02028408 Genomic DNA No translation available.
ABLF02028415 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7029.ACYPI004504-PA

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiACYPI004504-RA; ACYPI004504-PA; ACYPI004504

Phylogenomic databases

eggNOGiKOG1997 Eukaryota
ENOG410XNVY LUCA
InParanoidiJ9JVV8
OrthoDBi20156at2759
PhylomeDBiJ9JVV8

Family and domain databases

CDDicd08697 C2_Dock-D, 1 hit
Gene3Di2.30.29.30, 1 hit
2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR037809 C2_Dock-D
IPR035892 C2_domain_sf
IPR027007 DHR-1_domain
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
IPR021816 DOCK_C/D_N
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR23317 PTHR23317, 1 hit
PfamiView protein in Pfam
PF06920 DHR-2, 1 hit
PF14429 DOCK-C2, 1 hit
PF11878 DUF3398, 1 hit
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS51650 DHR_1, 1 hit
PS51651 DHR_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJ9JVV8_ACYPI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: J9JVV8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: May 14, 2014
Last modified: June 5, 2019
This is version 47 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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