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Protein
Submitted name:

TNF receptor-associated factor 4

Gene

TRAF4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri54 – 91TRAF-typePROSITE-ProRule annotationAdd BLAST38

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor-associated factor 4Imported
Gene namesi
Name:TRAF4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000076604.14
HGNCiHGNC:12034 TRAF4

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000076604

PTM / Processingi

Proteomic databases

MaxQBiJ9JIG0
PeptideAtlasiJ9JIG0
PRIDEiJ9JIG0

Expressioni

Gene expression databases

BgeeiENSG00000076604 Expressed in 205 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiJ9JIG0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ9JIG0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 91TRAF-typeInterPro annotationAdd BLAST38

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri54 – 91TRAF-typePROSITE-ProRule annotationAdd BLAST38

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0297 Eukaryota
ENOG410Z7YX LUCA
GeneTreeiENSGT00550000074359

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR008974 TRAF-like
IPR027138 TRAF4
IPR013083 Znf_RING/FYVE/PHD
IPR001293 Znf_TRAF
PANTHERiPTHR10131:SF118 PTHR10131:SF118, 1 hit
PfamiView protein in Pfam
PF02176 zf-TRAF, 1 hit
SUPFAMiSSF49599 SSF49599, 1 hit
PROSITEiView protein in PROSITE
PS50145 ZF_TRAF, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

J9JIG0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EGVFKCPEDQ LPLDYAKIYP DPELEVQVLG LPIRCIHSEE GCRWSGPLRH
60 70 80 90 100
LQGHLNTCSF NVIPCPNRCP MKLSRRDLPA HLQHDCPKRR LKAMRVCAPR
110
RVSTVRISVV PA
Length:112
Mass (Da):12,762
Last modified:October 31, 2012 - v1
Checksum:i1F49C408015740CD
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BUZ4TRAF4_HUMAN
TNF receptor-associated factor 4
TRAF4 CART1, MLN62, RNF83
470Annotation score:
F6SA91F6SA91_HUMAN
TNF receptor-associated factor 4
TRAF4
437Annotation score:
C9JJ10C9JJ10_HUMAN
TNF receptor-associated factor 4
TRAF4
182Annotation score:
A0A0C4DFM9A0A0C4DFM9_HUMAN
TNF receptor-associated factor 4
TRAF4
195Annotation score:
K7ER49K7ER49_HUMAN
TNF receptor-associated factor 4
TRAF4
90Annotation score:
Q2KJU6Q2KJU6_HUMAN
TNF receptor-associated factor 4
TRAF4
144Annotation score:
K7EJG7K7EJG7_HUMAN
TNF receptor-associated factor 4
TRAF4
48Annotation score:
K7EM06K7EM06_HUMAN
TNF receptor-associated factor 4
TRAF4
53Annotation score:
J3QR87J3QR87_HUMAN
TNF receptor-associated factor 4
TRAF4
49Annotation score:
J3QS94J3QS94_HUMAN
TNF receptor-associated factor 4
TRAF4
92Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010761 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000454852; ENSP00000396602; ENSG00000076604
UCSCiuc060des.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010761 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ9JIG0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ9JIG0
PeptideAtlasiJ9JIG0
PRIDEiJ9JIG0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000454852; ENSP00000396602; ENSG00000076604
UCSCiuc060des.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000076604.14
HGNCiHGNC:12034 TRAF4
OpenTargetsiENSG00000076604
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0297 Eukaryota
ENOG410Z7YX LUCA
GeneTreeiENSGT00550000074359

Miscellaneous databases

ChiTaRSiTRAF4 human

Gene expression databases

BgeeiENSG00000076604 Expressed in 205 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiJ9JIG0 baseline and differential

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR008974 TRAF-like
IPR027138 TRAF4
IPR013083 Znf_RING/FYVE/PHD
IPR001293 Znf_TRAF
PANTHERiPTHR10131:SF118 PTHR10131:SF118, 1 hit
PfamiView protein in Pfam
PF02176 zf-TRAF, 1 hit
SUPFAMiSSF49599 SSF49599, 1 hit
PROSITEiView protein in PROSITE
PS50145 ZF_TRAF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ9JIG0_HUMAN
AccessioniPrimary (citable) accession number: J9JIG0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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