Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - J9IRM2 (J9IRM2_9SPIT)

Entry version 19 (29 Sep 2021)
Sequence version 1 (31 Oct 2012)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

MAC/Perforin domain containing protein

Gene

OXYTRI_20266

Organism
Oxytricha trifallax
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Protein family/group databases

Transport Classification Database

More...TCDBi		1.C.39.7.3, the membrane attack complex/perforin (macpf) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MAC/Perforin domain containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:OXYTRI_20266Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOxytricha trifallaxImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1172189 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Sar › Alveolata › Ciliophora › Intramacronucleata › Spirotrichea › Stichotrichia › Sporadotrichida › Oxytrichidae › Oxytrichinae › Oxytricha
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006077 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

SecretedARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

Disulfide bondARBA annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 377MACPFInterPro annotationAdd BLAST327

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		1642796at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008979, Galactose-bd-like_sf
IPR020864, MACPF
IPR020863, MACPF_CS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01823, MACPF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00457, MACPF, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49785, SSF49785, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00279, MACPF_1, 1 hit
PS51412, MACPF_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

J9IRM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSQNRIRFT KVGSVLDCTY RPSLFPLIAL IAVNICTPVS SQDLFLKETA 
        60         70         80         90        100
GRDLIANAGD LTFPNIDYLA AGYNIFLGDP RSPHGIDPGF TNNFLFDFEN 
       110        120        130        140        150
QTLNGDKKYS IPHGVTVLSE FSCEASYSSQ VSTSASEYQS SMKQTMGMSV 
       160        170        180        190        200
EVSAMGGMGK GAFTGSQSFS SSLDVMQNQN SVIITSDSTC TAYTAGVQEF 
       210        220        230        240        250
NFPPQSKNLK TAVSLLSDVY EEEPYWRLID SFGTHYIKDI SMGSRFGYIY 
       260        270        280        290        300
TMTYYSYQSI ASQSSDQSFS VSVGVDAGIV AVSASVNYDT SQSSTQKTSI 
       310        320        330        340        350
SNQMTSTTQY SIGAKPPLNG DVSAWMQQNF TNPMPAIYNI QPIDHLIEFY 
       360        370        380        390        400
YNSTRPQVVQ NVKRALQSYC VHLGIIGYPV KCDGIINLSR QNLAVNAVAL 
       410        420        430        440        450
QNRAHESGYY QASNAIDGQN FFCSNSMSWQ GQSQSVATSE GSQAAYDSQY 
       460        470        480        490        500
ILLEFPEFYD VGDVLFYGRD QYQGKLKYLS LRVGNSSNAA ENVLCPGPSK 
       510        520        530        540        550
SLDAGVGIYR CKGIIGKYLF IQNSAANNFP LGYCEIEVYS FKNGQKYRTI 
       560        570        580        590        600
QGPNLLKGKS AITSHLPAYQ QYILWEPKKA LDGWTCGEVN CQSMYISAQN 
       610        620        630        640        650
IDTRNPYQWL NVDIVNATKI YIVKVYPRTS YTTQSQGISV WVGNNTIPHK 
       660        670        680        690        700
NKLCGRLTDY PFAFGGGSIK CDIVGRYVGF TSQLGVNGSD GYISLAEVEA 
       710        720        730        740        750
YTDSLSNLIS TDTAEVPQAP NLLFNKSVNS STVQPGSALN VASYAVDGSY 
       760        770        780        790        800
NVLPAGGCFV GASLPTQYLN VNMNSTNYVE YVKVAGRLDS MTWISMADNY 
       810        820        830        840        850
QIYVGNSTNI LENVACNGGQ IYNGSQVIPC QITGQYVGLL RTQISGIEPQ 
       860 
IMICEIQAFS Y
Length:861
Mass (Da):94,283
Last modified:October 31, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC248D6D76DDCE7C9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AMCR01006125 Genomic DNA Translation: EJY82214.1

Genome annotation databases

Ensembl protists genome annotation project

More...EnsemblProtistsi		EJY82214; EJY82214; OXYTRI_20266

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMCR01006125 Genomic DNA Translation: EJY82214.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein family/group databases

TCDBi1.C.39.7.3, the membrane attack complex/perforin (macpf) family

Genome annotation databases

EnsemblProtistsiEJY82214; EJY82214; OXYTRI_20266

Phylogenomic databases

OrthoDBi1642796at2759

Family and domain databases

InterProiView protein in InterPro
IPR008979, Galactose-bd-like_sf
IPR020864, MACPF
IPR020863, MACPF_CS
PfamiView protein in Pfam
PF01823, MACPF, 1 hit
SMARTiView protein in SMART
SM00457, MACPF, 1 hit
SUPFAMiSSF49785, SSF49785, 3 hits
PROSITEiView protein in PROSITE
PS00279, MACPF_1, 1 hit
PS51412, MACPF_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJ9IRM2_9SPIT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: J9IRM2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: September 29, 2021
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again