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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Bacillus cereus HuA2-1
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi487MagnesiumUniRule annotation1
Metal bindingi493MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:IG3_03338Imported
OrganismiBacillus cereus HuA2-1Imported
Taxonomic identifieri1053201 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000004136 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini623 – 691S1 motifInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili686 – 722Sequence analysisAdd BLAST37

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

J9BSC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEKQVFSI DLAGRQLTIE TSQLAKQANG AVLVRYGDTA VLSTATASKE
60 70 80 90 100
PKNVDFFPLT VNYEERLYAV GKIPGGFIKR EGRPSEKAIL ASRLIDRPIR
110 120 130 140 150
PLFADGFRNE VQVVSIVMSV DQDCSSEMAA MLGSSLALSI SDIPFEGPIA
160 170 180 190 200
GATVGRINGE FVINPTVEQQ EQSDMHLVVA GTKDAINMVE AGADQVPEET
210 220 230 240 250
MLEAIMFGHD EIKRLIAFQE EIVQAVGKEK TAVKLYEVDA DLNQAVREMA
260 270 280 290 300
ETDMHSAIQV HEKHAREDAI SVVKKRVIEH YEAEEADADT LGQVSEILYK
310 320 330 340 350
IVKEEVRRLI TVEKIRPDGR KGDEIRPLAS EVGILSRTHG SGLFTRGQTQ
360 370 380 390 400
ALSICTLGAL GDVQILDGLG VEESKRFMHH YNFPSFSVGE TRPMRGPGRR
410 420 430 440 450
EIGHGALGER ALEPVLPSEK DFPYTVRLVS EVLESNGSTS QASICGSTLA
460 470 480 490 500
MMDAGVPLKA PVAGIAMGLV KSGEHYTILT DIQGMEDHLG DMDFKVAGTA
510 520 530 540 550
KGVTALQMDI KIDGLSREIL EEALQQAKVG RMHILNHMLS VIAEPRIELS
560 570 580 590 600
AYAPKIITMA INPDKIRDVI GPSGKQINKI IEETGVKIDI EQDGTVFISS
610 620 630 640 650
INQEMNEKAK KIIEDIVREV QVGEIYLGKV KRVEKFGAFV ELFSGKDGLV
660 670 680 690 700
HISELALERV GKVEDVVKIG DEISVKVIEI DKQGRVNLSR KVLLKEEQEK
710 720
EAAKEEAAKE EAAKEENAQE QQ
Length:722
Mass (Da):79,134
Last modified:October 31, 2012 - v1
Checksum:i41A6D55F6E8059FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHDV01000024 Genomic DNA Translation: EJV81936.1
RefSeqiWP_002137924.1, NZ_JH804672.1

Genome annotation databases

EnsemblBacteriaiEJV81936; EJV81936; IG3_03338
PATRICifig|1053201.3.peg.3413

Similar proteinsi

Entry informationi

Entry nameiJ9BSC1_BACCE
AccessioniPrimary (citable) accession number: J9BSC1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: February 28, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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