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Entry version 76 (02 Dec 2020)
Sequence version 1 (31 Oct 2012)
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Protein

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Gene

pfs

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: L-methionine biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route).UniRule annotationARBA annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn_2), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (pfs), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn_1), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn_1), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn_2), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (CJU63_00850), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn_2), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtn_1), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN), 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN)
  2. Methylthioribose kinase (mtnK), Methylthioribose kinase (mtnK)
This subpathway is part of the pathway L-methionine biosynthesis via salvage pathway, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route), the pathway L-methionine biosynthesis via salvage pathway and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei12Proton acceptorUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei78Substrate; via amide nitrogenUniRule annotation1
Binding sitei152Substrate; via amide nitrogen and carbonyl oxygenUniRule annotation1
Active sitei197Proton donorUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseImported, Hydrolase
Biological processAmino-acid biosynthesis, Methionine biosynthesisUniRule annotationARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00904;UER00871

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseUniRule annotation (EC:3.2.2.9UniRule annotation)
Short name:
MTA/SAH nucleosidaseUniRule annotation
Short name:
MTANUniRule annotation
Alternative name(s):
5'-deoxyadenosine nucleosidaseUniRule annotation
Short name:
DOA nucleosidaseUniRule annotation
Short name:
dAdo nucleosidaseUniRule annotation
5'-methylthioadenosine nucleosidaseUniRule annotation
Short name:
MTA nucleosidaseUniRule annotation
S-adenosylhomocysteine nucleosidaseUniRule annotation
Short name:
AdoHcy nucleosidaseUniRule annotation
Short name:
SAH nucleosidaseUniRule annotation
Short name:
SRH nucleosidaseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pfsImported
Synonyms:mtnImported, mtnNUniRule annotationImported
ORF Names:A6V01_15400Imported, A9X72_20460Imported, AC789_1c01590Imported, ACN002_0164Imported, AML07_22980Imported, APZ14_11155Imported, AW106_08695Imported, BN17_45831Imported, BON72_09325Imported, BON76_15415Imported, BON94_19530Imported, C9162_08235Imported, C9306_11295Imported, C9Z89_09440Imported, CMR93_22910Imported, COD30_14825Imported, CR538_20695Imported, D5H35_11050Imported, D6004_09795Imported, D9610_09510Imported, D9F87_17280Imported, D9G95_20610Imported, D9S45_09875Imported, DAH32_15050Imported, DIV22_06210Imported, DL479_13410Imported, DL530_05630Imported, DL545_20445Imported, DL800_02435Imported, DLW60_08705Imported, DM155_08280Imported, DQF57_05720Imported, DQF71_09570Imported, DS143_09160Imported, DS732_05720Imported, DVB38_09225Imported, E2855_00156Imported, E2863_00154Imported, EA223_13340Imported, EAM59_13775Imported, EAN70_14230Imported, EBM08_07015Imported, EC95NR1_04344Imported, ED600_04695Imported, EG599_10080Imported, EH412_11940Imported, EHJ36_11805Imported, EJ366_18250Imported, EKI52_10485Imported, ELY05_11430Imported, ERS150876_00075Imported, F7F00_13180Imported, F7F23_12970Imported, F7F26_13580Imported, G5668_12535Imported, G5670_12875Imported, G5680_11490Imported, GP698_00205Imported, NCTC8960_01573Imported, NCTC9055_00976Imported, RX35_04894Imported, SAMEA3472114_03629Imported, SAMEA3753064_03361Imported, SAMEA3753290_00384Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL3603731

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2 – 226PNP_UDP_1InterPro annotationAdd BLAST225

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni173 – 174Substrate bindingUniRule annotation2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.UniRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1580, 1 hit

HAMAP database of protein families

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HAMAPi
MF_01684, Salvage_MtnN, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR010049, MTA_SAH_Nsdase
IPR000845, Nucleoside_phosphorylase_d
IPR035994, Nucleoside_phosphorylase_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01048, PNP_UDP_1, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF53167, SSF53167, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01704, MTA/SAH-Nsdase, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

J7QX79-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIGIIGAME EEVTLLRDKI EKRQTISLGG CEIYTGQLNG TEVALLKSGI
60 70 80 90 100
GKVAAALGAT LLLEHCKPDV IINTGSAGGL APTLKVGDIV VSDEARYHDA
110 120 130 140 150
DVTAFGYEYG QLPGCPAGFK ADDKLIAAAE ACIAELNLNA VRGLIVSGDA
160 170 180 190 200
FINGSVGLAK IRHNFPQAIA VEMEATAIAH VCHNFNVPFV VVRAISDVAD
210 220 230
QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG
Length:232
Mass (Da):24,368
Last modified:October 31, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE3FAA0B93CEF999
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP010315 Genomic DNA Translation: AJE54458.1
CP007491 Genomic DNA Translation: ALY11622.1
CP021339 Genomic DNA Translation: ART22708.1
CP024141 Genomic DNA Translation: AUK02629.1
CP020520 Genomic DNA Translation: AVU67413.1
CP029692 Genomic DNA Translation: AWS34828.1
CP031546 Genomic DNA Translation: AXO05896.1
CP031653 Genomic DNA Translation: AXP28209.1
AP018796 Genomic DNA Translation: BBF45796.1
AP018802 Genomic DNA Translation: BBF51686.1
HE964769 Genomic DNA Translation: CCJ42630.1
CYGC01000001 Genomic DNA Translation: CTZ20587.1
AAAAJM010000012 Genomic DNA Translation: EAA0808685.1
AAAAMW010000019 Genomic DNA Translation: EAA1295158.1
AAAANM010000008 Genomic DNA Translation: EAA1303245.1
AAAASG010000011 Genomic DNA Translation: EAA1895366.1
AAABQM010000014 Genomic DNA Translation: EAA4935135.1
AAACLF010000022 Genomic DNA Translation: EAA7471675.1
AAADKN010000016 Genomic DNA Translation: EAB0452762.1
AAADJV010000018 Genomic DNA Translation: EAB0524107.1
AAADKK010000019 Genomic DNA Translation: EAB0592467.1
AAADOF010000015 Genomic DNA Translation: EAB1108633.1
AAADOH010000015 Genomic DNA Translation: EAB1134306.1
AAAFEB010000014 Genomic DNA Translation: EAB5836007.1
AAAFJW010000015 Genomic DNA Translation: EAB6610927.1
AAAFQE010000014 Genomic DNA Translation: EAB7435762.1
AAAGRT010000011 Genomic DNA Translation: EAC0707039.1
AAAGSA010000013 Genomic DNA Translation: EAC0772358.1
AAAGUG010000013 Genomic DNA Translation: EAC1022539.1
AAAGXV010000022 Genomic DNA Translation: EAC1382035.1
AAAHAR010000011 Genomic DNA Translation: EAC1628016.1
RYCV01000003 Genomic DNA Translation: KAA0029356.1
RDUQ01000045 Genomic DNA Translation: KAA2012473.1
VZFA01000018 Genomic DNA Translation: KAB0064628.1
VZEX01000018 Genomic DNA Translation: KAB0086985.1
VZEA01000017 Genomic DNA Translation: KAB0221607.1
WSGY01000001 Genomic DNA Translation: KAE9891472.1
LMBK01000335 Genomic DNA Translation: KST30953.1
LOFS01000184 Genomic DNA Translation: KYR47061.1
RNIM01000008 Genomic DNA Translation: MFY68600.1
RUYU01000004 Genomic DNA Translation: MLK50369.1
JAAKDC010000017 Genomic DNA Translation: NGG75363.1
JAAKDA010000018 Genomic DNA Translation: NGH88781.1
JAAKCQ010000016 Genomic DNA Translation: NGK63930.1
NENZ01000013 Genomic DNA Translation: OTE01148.1
LEOO01000028 Genomic DNA Translation: OYC64474.1
NTMU01000056 Genomic DNA Translation: PBK16849.1
NWBE01000018 Genomic DNA Translation: PBR09613.1
NWRP01000031 Genomic DNA Translation: PDV93498.1
QFSS01000017 Genomic DNA Translation: PZZ72450.1
CP037945 Genomic DNA Translation: QBO39375.1
UCWO01000013 Genomic DNA Translation: SQM91561.1
UCYS01000001 Genomic DNA Translation: SQP29823.1
UCZX01000012 Genomic DNA Translation: SQQ85314.1
UGCS01000002 Genomic DNA Translation: STI99311.1
UGFO01000006 Genomic DNA Translation: STN11363.1
MTXF01000067 Genomic DNA Translation: TEZ52885.1
MTXJ01000059 Genomic DNA Translation: TEZ67183.1
MTYB01000095 Genomic DNA Translation: TFA52627.1
RZFP01000023 Genomic DNA Translation: TFM31869.1
QAFD01000018 Genomic DNA Translation: TGG10334.1
RRSF01000024 Genomic DNA Translation: TJA70397.1
RRNK01000003 Genomic DNA Translation: TJH01386.1
RRHE01000013 Genomic DNA Translation: TJP28692.1

NCBI Reference Sequences

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RefSeqi
WP_000689833.1, NZ_WVUT01000024.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AJE54458; AJE54458; AC789_1c01590
ALY11622; ALY11622; ACN002_0164
ALZ67156; ALZ67156; AWH59_13765
AOM48011; AOM48011; FORC28_5035
CTZ20587; CTZ20587; ERS150876_00075
KIQ45373; KIQ45373; IY32_16590
KST30953; KST30953; APZ14_11155
KYR47061; KYR47061; AML07_22980
ODA84547; ODA84547; A9D65_13030

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.10474.peg.1370

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP010315 Genomic DNA Translation: AJE54458.1
CP007491 Genomic DNA Translation: ALY11622.1
CP021339 Genomic DNA Translation: ART22708.1
CP024141 Genomic DNA Translation: AUK02629.1
CP020520 Genomic DNA Translation: AVU67413.1
CP029692 Genomic DNA Translation: AWS34828.1
CP031546 Genomic DNA Translation: AXO05896.1
CP031653 Genomic DNA Translation: AXP28209.1
AP018796 Genomic DNA Translation: BBF45796.1
AP018802 Genomic DNA Translation: BBF51686.1
HE964769 Genomic DNA Translation: CCJ42630.1
CYGC01000001 Genomic DNA Translation: CTZ20587.1
AAAAJM010000012 Genomic DNA Translation: EAA0808685.1
AAAAMW010000019 Genomic DNA Translation: EAA1295158.1
AAAANM010000008 Genomic DNA Translation: EAA1303245.1
AAAASG010000011 Genomic DNA Translation: EAA1895366.1
AAABQM010000014 Genomic DNA Translation: EAA4935135.1
AAACLF010000022 Genomic DNA Translation: EAA7471675.1
AAADKN010000016 Genomic DNA Translation: EAB0452762.1
AAADJV010000018 Genomic DNA Translation: EAB0524107.1
AAADKK010000019 Genomic DNA Translation: EAB0592467.1
AAADOF010000015 Genomic DNA Translation: EAB1108633.1
AAADOH010000015 Genomic DNA Translation: EAB1134306.1
AAAFEB010000014 Genomic DNA Translation: EAB5836007.1
AAAFJW010000015 Genomic DNA Translation: EAB6610927.1
AAAFQE010000014 Genomic DNA Translation: EAB7435762.1
AAAGRT010000011 Genomic DNA Translation: EAC0707039.1
AAAGSA010000013 Genomic DNA Translation: EAC0772358.1
AAAGUG010000013 Genomic DNA Translation: EAC1022539.1
AAAGXV010000022 Genomic DNA Translation: EAC1382035.1
AAAHAR010000011 Genomic DNA Translation: EAC1628016.1
RYCV01000003 Genomic DNA Translation: KAA0029356.1
RDUQ01000045 Genomic DNA Translation: KAA2012473.1
VZFA01000018 Genomic DNA Translation: KAB0064628.1
VZEX01000018 Genomic DNA Translation: KAB0086985.1
VZEA01000017 Genomic DNA Translation: KAB0221607.1
WSGY01000001 Genomic DNA Translation: KAE9891472.1
LMBK01000335 Genomic DNA Translation: KST30953.1
LOFS01000184 Genomic DNA Translation: KYR47061.1
RNIM01000008 Genomic DNA Translation: MFY68600.1
RUYU01000004 Genomic DNA Translation: MLK50369.1
JAAKDC010000017 Genomic DNA Translation: NGG75363.1
JAAKDA010000018 Genomic DNA Translation: NGH88781.1
JAAKCQ010000016 Genomic DNA Translation: NGK63930.1
NENZ01000013 Genomic DNA Translation: OTE01148.1
LEOO01000028 Genomic DNA Translation: OYC64474.1
NTMU01000056 Genomic DNA Translation: PBK16849.1
NWBE01000018 Genomic DNA Translation: PBR09613.1
NWRP01000031 Genomic DNA Translation: PDV93498.1
QFSS01000017 Genomic DNA Translation: PZZ72450.1
CP037945 Genomic DNA Translation: QBO39375.1
UCWO01000013 Genomic DNA Translation: SQM91561.1
UCYS01000001 Genomic DNA Translation: SQP29823.1
UCZX01000012 Genomic DNA Translation: SQQ85314.1
UGCS01000002 Genomic DNA Translation: STI99311.1
UGFO01000006 Genomic DNA Translation: STN11363.1
MTXF01000067 Genomic DNA Translation: TEZ52885.1
MTXJ01000059 Genomic DNA Translation: TEZ67183.1
MTYB01000095 Genomic DNA Translation: TFA52627.1
RZFP01000023 Genomic DNA Translation: TFM31869.1
QAFD01000018 Genomic DNA Translation: TGG10334.1
RRSF01000024 Genomic DNA Translation: TJA70397.1
RRNK01000003 Genomic DNA Translation: TJH01386.1
RRHE01000013 Genomic DNA Translation: TJP28692.1
RefSeqiWP_000689833.1, NZ_WVUT01000024.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Chemistry databases

ChEMBLiCHEMBL3603731

Genome annotation databases

EnsemblBacteriaiAJE54458; AJE54458; AC789_1c01590
ALY11622; ALY11622; ACN002_0164
ALZ67156; ALZ67156; AWH59_13765
AOM48011; AOM48011; FORC28_5035
CTZ20587; CTZ20587; ERS150876_00075
KIQ45373; KIQ45373; IY32_16590
KST30953; KST30953; APZ14_11155
KYR47061; KYR47061; AML07_22980
ODA84547; ODA84547; A9D65_13030
PATRICifig|562.10474.peg.1370

Enzyme and pathway databases

UniPathwayiUPA00904;UER00871

Family and domain databases

Gene3Di3.40.50.1580, 1 hit
HAMAPiMF_01684, Salvage_MtnN, 1 hit
InterProiView protein in InterPro
IPR010049, MTA_SAH_Nsdase
IPR000845, Nucleoside_phosphorylase_d
IPR035994, Nucleoside_phosphorylase_sf
PfamiView protein in Pfam
PF01048, PNP_UDP_1, 1 hit
SUPFAMiSSF53167, SSF53167, 1 hit
TIGRFAMsiTIGR01704, MTA/SAH-Nsdase, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJ7QX79_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: J7QX79
Secondary accession number(s): A0A2A2XQE9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 31, 2012
Last sequence update: October 31, 2012
Last modified: December 2, 2020
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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