UniProtKB - J3QT73 (J3QT73_HUMAN)

BLAST

>tr|J3QT73|J3QT73_HUMAN COP9 signalosome complex subunit 7b (Fragment) OS=Homo sapiens OX=9606 GN=COPS7B PE=1 SV=1
YTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRAN
QYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKV
KGPSCPLELPANACSPKIFNSSWLHLGRDGGIDAPLSAEGPVAASVFSPLLG

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History
Entry version 40 (12 Sep 2018)
Sequence version 1 (03 Oct 2012)
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Protein

Submitted name:

COP9 signalosome complex subunit 7b

Gene

COPS7B

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: COP9 signalosome complex subunit 7bImported
Gene namesⁱ	Name:COPS7BImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 2

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000144524.17
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:16760 COPS7B

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000144524

OpenTargetsⁱ

ENSG00000144524

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	J3QT73
PeptideAtlas More...PeptideAtlasⁱ	J3QT73
PRIDEⁱ	J3QT73

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000144524 Expressed in 199 organ(s), highest expression level in pituitary gland
ExpressionAtlasⁱ	J3QT73 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	J3QT73
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	52 – 83	Sequence analysisAdd BLAST		32

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG3250 Eukaryota ENOG410XP7W LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000013069

Family and domain databases

InterProⁱ	View protein in InterPro IPR027530 Csn7b
PANTHERⁱ	PTHR15350:SF8 PTHR15350:SF8, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show all Align All

J3QT73-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
YTDIIQGKLD QRNQLLEVDF CIGRDIRKKD INNIVKTLHE WCDGCEAVLL 
        60         70         80         90        100
GIEQQVLRAN QYKENHNRTQ QQVEAEVTNI KKTLKATASS SAQEMEQQLA 
       110        120        130        140        150
ERECPPHAEQ RQPTKKMSKV KGPSCPLELP ANACSPKIFN SSWLHLGRDG 
       160        170 
GIDAPLSAEG PVAASVFSPL LG

Length:172

Mass (Da):19,090

Last modified:October 3, 2012 - v1

Checksum:ⁱFC04D1A68CFE06DD

Computationally mapped potential isoform sequencesⁱ

There are 12 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name	Protein names	Gene names	Length	Annotation

	Q9H9Q2	CSN7B_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b, SGN7b, Signalosome subunit 7b (JAB1-containing signalosome subunit 7b)	COPS7B CSN7B	264	Annotation score:
	J3KQ34	J3KQ34_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	230	Annotation score:
	A0A087X1P5	A0A087X1P5_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	209	Annotation score:
	J3KQ41	J3KQ41_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	278	Annotation score:
	J3QT95	J3QT95_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	150	Annotation score:
	J3QT43	J3QT43_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	103	Annotation score:
	J3QT67	J3QT67_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	62	Annotation score:
	J3QT50	J3QT50_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	78	Annotation score:
	J3QT69	J3QT69_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	68	Annotation score:
	J3KQV6	J3KQV6_HUMAN	COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 7b	COPS7B	54	Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC073476 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC073476 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000449174; ENSP00000403300; ENSG00000144524
UCSC genome browser More...UCSCⁱ	uc061toh.1 human

Protein	Similar proteins		Species	Score	Length	Source
J3QT73	COPS7B isoform 11 (Fragment)		PANTR		172	UniRef100_J3QT73

Protein	Similar proteins		Species	Score	Length	Source
J3QT73	COPS7B isoform 11 (Fragment)		PANTR		172	UniRef90_J3QT73
COPS7B isoform 10 (Fragment)		PONAB		171

Protein	Similar proteins		Species	Score	Length	Source
J3QT73	COPS7B isoform 11 (Fragment)		PANTR		172	UniRef50_J3QT73
COPS7B isoform 10 (Fragment)		PONAB		171
COP9 signalosome complex subunit 7b isoform X4		ALLSI		215
Uncharacterized protein		SAIBB		178
COP9 signalosome complex subunit 7b		TUPCH		196
+9

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC073476 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC073476 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	J3QT73
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQBⁱ	J3QT73
PeptideAtlasⁱ	J3QT73
PRIDEⁱ	J3QT73

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000449174; ENSP00000403300; ENSG00000144524
UCSCⁱ	uc061toh.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000144524.17
HGNCⁱ	HGNC:16760 COPS7B
OpenTargetsⁱ	ENSG00000144524
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3250 Eukaryota ENOG410XP7W LUCA
GeneTreeⁱ	ENSGT00390000013069

Miscellaneous databases

ChiTaRSⁱ	COPS7B human

ChiTaRSⁱ

COPS7B human

Gene expression databases

Bgeeⁱ	ENSG00000144524 Expressed in 199 organ(s), highest expression level in pituitary gland
ExpressionAtlasⁱ	J3QT73 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR027530 Csn7b
PANTHERⁱ	PTHR15350:SF8 PTHR15350:SF8, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	J3QT73_HUMAN
Accessionⁱ	J3QT73Primary (citable) accession number: J3QT73
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 3, 2012
	Last sequence update:	October 3, 2012
	Last modified:	September 12, 2018
	This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - J3QT73 (J3QT73_HUMAN)

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COP9 signalosome complex subunit 7b

COPS7B

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ