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Protein
Submitted name:

Protein CASC3

Gene

CASC3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CASC3Imported
Gene namesi
Name:CASC3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000108349.14
HGNCiHGNC:17040 CASC3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000108349

PTM / Processingi

Proteomic databases

MaxQBiJ3QSC4
PeptideAtlasiJ3QSC4
PRIDEiJ3QSC4

Expressioni

Gene expression databases

BgeeiENSG00000108349 Expressed in 233 organ(s), highest expression level in middle frontal gyrus
ExpressionAtlasiJ3QSC4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3QSC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4264 Eukaryota
ENOG410ZW5Y LUCA
GeneTreeiENSGT00390000006930

Family and domain databases

InterProiView protein in InterPro
IPR028544 CASC3
PANTHERiPTHR13434 PTHR13434, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

J3QSC4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XARRTRTKVG DAVKLAEEVP PPPEGLIPAP PVPETTPTPP TKTGTWEAPV
60 70 80 90 100
DSSTSGLEQD VAQLNIAEQN WSPGQPSFLQ PRELRGMPNH IHMGAGPPPQ
110 120
FNRMEEMLTL QISIKYLPCT KCFSTPKGR
Length:129
Mass (Da):14,087
Last modified:October 3, 2012 - v1
Checksum:i65235816F35280ED
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15234CASC3_HUMAN
Protein CASC3
CASC3 MLN51
703Annotation score:
J3KSY7J3KSY7_HUMAN
Protein CASC3
CASC3
223Annotation score:
K7EQ38K7EQ38_HUMAN
Protein CASC3
CASC3
66Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068669 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000577605; ENSP00000464626; ENSG00000108349
UCSCiuc060exg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068669 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ3QSC4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ3QSC4
PeptideAtlasiJ3QSC4
PRIDEiJ3QSC4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000577605; ENSP00000464626; ENSG00000108349
UCSCiuc060exg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000108349.14
HGNCiHGNC:17040 CASC3
OpenTargetsiENSG00000108349
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4264 Eukaryota
ENOG410ZW5Y LUCA
GeneTreeiENSGT00390000006930

Miscellaneous databases

ChiTaRSiCASC3 human

Gene expression databases

BgeeiENSG00000108349 Expressed in 233 organ(s), highest expression level in middle frontal gyrus
ExpressionAtlasiJ3QSC4 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR028544 CASC3
PANTHERiPTHR13434 PTHR13434, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3QSC4_HUMAN
AccessioniPrimary (citable) accession number: J3QSC4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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