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Protein
Submitted name:

Fatty acid 2-hydroxylase

Gene

FA2H

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty acid 2-hydroxylaseImported
Gene namesi
Name:FA2HImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000103089.8
HGNCiHGNC:21197 FA2H

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei148 – 167HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000103089

PTM / Processingi

Proteomic databases

MaxQBiJ3QS89
PeptideAtlasiJ3QS89
PRIDEiJ3QS89

Expressioni

Gene expression databases

BgeeiENSG00000103089 Expressed in 153 organ(s), highest expression level in C1 segment of cervical spinal cord
ExpressionAtlasiJ3QS89 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3QS89
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0539 Eukaryota
COG3000 LUCA
GeneTreeiENSGT00390000002142

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

J3QS89-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSFQLPAMA TSTMASFSHK DTEKGSMENE PVALEETQKT DPAMEPRFKV
60 70 80 90 100
VDWDKDLVDW RKPLLWQVGH LGEKYDEWVH QPVTRPIRLF HSDLIEGLSK
110 120 130 140 150
TVWYSVPIIW VPLVLYLSWS YYRTFAQGNV RLFTSFTTEY TVAVPKSMFP
160 170 180 190
GLFMLGTFLW SLIEYLIHRF LFHMKPPSDS YYLIMLHFVM HG
Length:192
Mass (Da):22,588
Last modified:October 3, 2012 - v1
Checksum:i0E9877B95C31CEBC
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7L5A8FA2H_HUMAN
Fatty acid 2-hydroxylase
FA2H FAAH
372Annotation score:
H3BP32H3BP32_HUMAN
Fatty acid 2-hydroxylase
FA2H
156Annotation score:
A0A087WVM8A0A087WVM8_HUMAN
Fatty acid 2-hydroxylase
FA2H
18Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei192Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004685 Genomic DNA No translation available.
AC009132 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000569949; ENSP00000464576; ENSG00000103089
UCSCiuc059xdd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004685 Genomic DNA No translation available.
AC009132 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ3QS89
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ3QS89
PeptideAtlasiJ3QS89
PRIDEiJ3QS89

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000569949; ENSP00000464576; ENSG00000103089
UCSCiuc059xdd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000103089.8
HGNCiHGNC:21197 FA2H
OpenTargetsiENSG00000103089
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0539 Eukaryota
COG3000 LUCA
GeneTreeiENSGT00390000002142

Gene expression databases

BgeeiENSG00000103089 Expressed in 153 organ(s), highest expression level in C1 segment of cervical spinal cord
ExpressionAtlasiJ3QS89 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiJ3QS89_HUMAN
AccessioniPrimary (citable) accession number: J3QS89
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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