UniProtKB - J3QRG6 (J3QRG6_HUMAN)
Protein
Submitted name:
Cyclin-dependent kinase inhibitor 2A
Gene
CDKN2A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Cyclin-dependent kinase inhibitor 2AImported |
Gene namesi | Name:CDKN2AImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000147889.16 |
HGNCi | HGNC:1787, CDKN2A |
Expressioni
Gene expression databases
Bgeei | ENSG00000147889, Expressed in adenohypophysis and 208 other tissues |
ExpressionAtlasi | J3QRG6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 128 | ANK_REP_REGIONInterPro annotationAdd BLAST | 113 |
Keywords - Domaini
ANK repeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000163078 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
J3QRG6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPAAGSSME PSADWLATAA ARGRVEEVRA LLEAGALPNA PNSYGRRPIQ
60 70 80 90 100
VMMMGSARVA ELLLLHGAEP NCADPATLTR PVHDAAREGF LDTLVVLHRA
110 120 130
GARLDVRDAW GRLPVDLAEE LGHRDVARHP RLKEPERL
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP42771 | CDN2A_HUMAN | Cyclin-dependent kinase inhibitor 2... | CDKN2A CDKN2, MTS1 | 156 | Annotation score: | ||
Q8N726 | ARF_HUMAN | Tumor suppressor ARF | CDKN2A CDKN2, MLM | 132 | Annotation score: | ||
K7ENC6 | K7ENC6_HUMAN | Cyclin-dependent kinase inhibitor 2... | CDKN2A | 121 | Annotation score: | ||
K7ES20 | K7ES20_HUMAN | Cyclin-dependent kinase inhibitor 2... | CDKN2A | 104 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL449423 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000579122; ENSP00000464202; ENSG00000147889 |
UCSCi | uc064skb.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL449423 Genomic DNA No translation available. |
3D structure databases
SMRi | J3QRG6 |
ModBasei | Search... |
Proteomic databases
MaxQBi | J3QRG6 |
PeptideAtlasi | J3QRG6 |
PRIDEi | J3QRG6 |
Protocols and materials databases
Antibodypediai | 3608, 1402 antibodies |
Genome annotation databases
Ensembli | ENST00000579122; ENSP00000464202; ENSG00000147889 |
UCSCi | uc064skb.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000147889.16 |
HGNCi | HGNC:1787, CDKN2A |
OpenTargetsi | ENSG00000147889 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000163078 |
Miscellaneous databases
ChiTaRSi | CDKN2A, human |
Gene expression databases
Bgeei | ENSG00000147889, Expressed in adenohypophysis and 208 other tissues |
ExpressionAtlasi | J3QRG6, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | J3QRG6_HUMAN | |
Accessioni | J3QRG6Primary (citable) accession number: J3QRG6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2012 |
Last sequence update: | October 3, 2012 | |
Last modified: | August 12, 2020 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |