Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Axin-2

Gene

AXIN2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Axin-2Imported
Gene namesi
Name:AXIN2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000168646.12
HGNCiHGNC:904 AXIN2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168646

PTM / Processingi

Proteomic databases

PeptideAtlasiJ3QQJ3
PRIDEiJ3QQJ3

Expressioni

Gene expression databases

BgeeiENSG00000168646 Expressed in 174 organ(s), highest expression level in female gonad
ExpressionAtlasiJ3QQJ3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3QQJ3
SMRiJ3QQJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 192RGSInterPro annotationAdd BLAST112

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00390000010011

Family and domain databases

CDDicd11582 Axin_TNKS_binding, 1 hit
Gene3Di1.10.196.10, 1 hit
InterProiView protein in InterPro
IPR032101 Axin_TNKS-bd
IPR016137 RGS
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
PfamiView protein in Pfam
PF16646 AXIN1_TNKS_BD, 1 hit
PF00615 RGS, 1 hit
PRINTSiPR01301 RGSPROTEIN
SMARTiView protein in SMART
SM00315 RGS, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
PROSITEiView protein in PROSITE
PS50132 RGS, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

J3QQJ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSAMLVTCL PDPSSSFRED APRPPVPGEE GETPPCQPGV GKGQVTKPMP
60 70 80 90 100
VSSNTRRNED GLGEPEGRAS PDSPLTRWTK SLHSLLGDQD GAYLFRTFLE
110 120 130 140 150
REKCVDTLDF WFACNGFRQM NLKDTKTLRV AKAIYKRYIE NNSIVSKQLK
160 170 180 190
PATKTYIRDG IKKQQIDSIM FDQAQTEIQS VMEENAYQMF LT
Length:192
Mass (Da):21,616
Last modified:October 3, 2012 - v1
Checksum:i19C5A8ADAB999258
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y2T1AXIN2_HUMAN
Axin-2
AXIN2
843Annotation score:
E7ES00E7ES00_HUMAN
Axin-2
AXIN2
778Annotation score:
J3QRK4J3QRK4_HUMAN
Axin-2
AXIN2
271Annotation score:
F5GX43F5GX43_HUMAN
Axin-2
AXIN2
150Annotation score:
A0A087WXP8A0A087WXP8_HUMAN
Axin-2
AXIN2
160Annotation score:
A0A1B0GX50A0A1B0GX50_HUMAN
Axin-2
AXIN2
191Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei192Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115994 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000580513; ENSP00000463761; ENSG00000168646
UCSCiuc060izb.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC115994 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ3QQJ3
SMRiJ3QQJ3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiJ3QQJ3
PRIDEiJ3QQJ3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000580513; ENSP00000463761; ENSG00000168646
UCSCiuc060izb.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168646.12
HGNCiHGNC:904 AXIN2
OpenTargetsiENSG00000168646
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00390000010011

Miscellaneous databases

ChiTaRSiAXIN2 human

Gene expression databases

BgeeiENSG00000168646 Expressed in 174 organ(s), highest expression level in female gonad
ExpressionAtlasiJ3QQJ3 baseline and differential

Family and domain databases

CDDicd11582 Axin_TNKS_binding, 1 hit
Gene3Di1.10.196.10, 1 hit
InterProiView protein in InterPro
IPR032101 Axin_TNKS-bd
IPR016137 RGS
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
PfamiView protein in Pfam
PF16646 AXIN1_TNKS_BD, 1 hit
PF00615 RGS, 1 hit
PRINTSiPR01301 RGSPROTEIN
SMARTiView protein in SMART
SM00315 RGS, 1 hit
SUPFAMiSSF48097 SSF48097, 1 hit
PROSITEiView protein in PROSITE
PS50132 RGS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3QQJ3_HUMAN
AccessioniPrimary (citable) accession number: J3QQJ3
Secondary accession number(s): A0A0A6YYN5, A0A0K0K1H4, J3QKQ7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again