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Protein

Cilia- and flagella-associated protein 73

Gene

Cfap73

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Cilia- and flagella-associated protein 73Curated
Alternative name(s):
Coiled-coil domain-containing protein 42BImported
Gene namesi
Name:Cfap73Imported
Synonyms:Ccdc42bImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:3779542 Cfap73

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004374811 – 306Cilia- and flagella-associated protein 73Add BLAST306

Proteomic databases

MaxQBiJ3QPZ5
PaxDbiJ3QPZ5
PRIDEiJ3QPZ5

Expressioni

Gene expression databases

BgeeiENSMUSG00000094282 Expressed in 15 organ(s), highest expression level in testis

Structurei

3D structure databases

SMRiJ3QPZ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili49 – 139Sequence analysisAdd BLAST91
Coiled coili197 – 231Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the CFAP73 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IG5M Eukaryota
ENOG4111NGK LUCA
GeneTreeiENSGT00390000018178
InParanoidiJ3QPZ5
OMAiNLFQLVC
OrthoDBiEOG091G0B7C
TreeFamiTF327270

Family and domain databases

InterProiView protein in InterPro
IPR025252 DUF4200
PfamiView protein in Pfam
PF13863 DUF4200, 1 hit

Sequencei

Sequence statusi: Complete.

J3QPZ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVTWEEYFR LVFSEKVQPK PLEQTGDDSS VLQLILEKKE ELAVADLGLQ
60 70 80 90 100
AQKKEYRSTI ESVNQRWREL EQKGQELQGS VISYDKFLKE VEARRAARKA
110 120 130 140 150
IEERKITGNL DAELRRLRTQ LKELRLQRAR LQRKVQRLEP CARILKRALE
160 170 180 190 200
KRPVFEEVSD LVARFETLVS TKAALKLEEQ KRLVEMESTR AQLLSLQSEK
210 220 230 240 250
QDEMLNLNQQ RTQLVEQLEA AREHRQQWES KWTEILNSAS EKTLLLGRAR
260 270 280 290 300
MAVLNLYHLV RLQQGRRQTL DVRDVEGQLE EVKRFIMNIS ATLAKLALAQ

PTATAS
Length:306
Mass (Da):35,671
Last modified:October 3, 2012 - v1
Checksum:i152E0FF0C7B831DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125183 Genomic DNA No translation available.
CCDSiCCDS57376.1
RefSeqiNP_001182023.1, NM_001195094.1
UniGeneiMm.464847

Genome annotation databases

EnsembliENSMUST00000177908; ENSMUSP00000137554; ENSMUSG00000094282
GeneIDi546886
KEGGimmu:546886
UCSCiuc012ecs.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125183 Genomic DNA No translation available.
CCDSiCCDS57376.1
RefSeqiNP_001182023.1, NM_001195094.1
UniGeneiMm.464847

3D structure databases

SMRiJ3QPZ5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ3QPZ5
PaxDbiJ3QPZ5
PRIDEiJ3QPZ5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000177908; ENSMUSP00000137554; ENSMUSG00000094282
GeneIDi546886
KEGGimmu:546886
UCSCiuc012ecs.1 mouse

Organism-specific databases

CTDi387885
MGIiMGI:3779542 Cfap73

Phylogenomic databases

eggNOGiENOG410IG5M Eukaryota
ENOG4111NGK LUCA
GeneTreeiENSGT00390000018178
InParanoidiJ3QPZ5
OMAiNLFQLVC
OrthoDBiEOG091G0B7C
TreeFamiTF327270

Miscellaneous databases

PROiPR:J3QPZ5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000094282 Expressed in 15 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR025252 DUF4200
PfamiView protein in Pfam
PF13863 DUF4200, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCFA73_MOUSE
AccessioniPrimary (citable) accession number: J3QPZ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2016
Last sequence update: October 3, 2012
Last modified: November 7, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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