Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospholipid scramblase

Gene

Plscr5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.UniRule annotation

Cofactori

Ca2+UniRule annotation

GO - Molecular functioni

  • phospholipid scramblase activity Source: GO_Central

GO - Biological processi

Keywordsi

LigandCalciumUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Phospholipid scramblaseUniRule annotation
Gene namesi
Name:Plscr5Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:3779462 Plscr5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

Lipoprotein, PalmitateUniRule annotation

Proteomic databases

PaxDbiJ3QM92
PRIDEiJ3QM92

PTM databases

iPTMnetiJ3QM92
PhosphoSitePlusiJ3QM92

Expressioni

Gene expression databases

BgeeiENSMUSG00000095654 Expressed in 11 organ(s), highest expression level in heart

Structurei

3D structure databases

ProteinModelPortaliJ3QM92
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phospholipid scramblase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0621 Eukaryota
ENOG410XSYS LUCA
GeneTreeiENSGT00390000002884
InParanoidiJ3QM92
OMAiGYVAQKW
OrthoDBiEOG091G0CUL
TreeFamiTF314939

Family and domain databases

InterProiView protein in InterPro
IPR005552 Scramblase
IPR025659 Tubby-like_C
PANTHERiPTHR23248 PTHR23248, 1 hit
PfamiView protein in Pfam
PF03803 Scramblase, 1 hit
SUPFAMiSSF54518 SSF54518, 1 hit

Sequencei

Sequence statusi: Complete.

J3QM92-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASKDSQNQN PRSLPGFLPR ATNPDQNSQE ASSNPRKQAR QQPGVSQPSS
60 70 80 90 100
FLPTATLPPG LEYLSQLDLI IIHQQVELLG MILGTETSNK YEIKNSLGQR
110 120 130 140 150
IYFAVEESIC FNRNVCSTLR ACTLRITDNS GREVITVNRP LRCNSCWCPC
160 170 180 190 200
YLQELEIQAP PGTIVGYVAQ KWGPFQPKFT IQNANKEDIL KIIGPCTTCG
210 220 230 240 250
CFGDVDFEVK TVDEKVTIGK ISKYWSGFVN DVFTNADNFG IHVPADLDVT
260 270
LKAAMIGACF LFDFMFFEHS LAGL
Length:274
Mass (Da):30,412
Last modified:October 3, 2012 - v1
Checksum:iDFECF78B31E46530
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC111125 Genomic DNA No translation available.
RefSeqiNP_001182622.1, NM_001195693.1
XP_006510799.1, XM_006510736.2
XP_006510800.1, XM_006510737.2
UniGeneiMm.464262

Genome annotation databases

EnsembliENSMUST00000179751; ENSMUSP00000136181; ENSMUSG00000095654
GeneIDi100504689
KEGGimmu:100504689
UCSCiuc012gyj.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC111125 Genomic DNA No translation available.
RefSeqiNP_001182622.1, NM_001195693.1
XP_006510799.1, XM_006510736.2
XP_006510800.1, XM_006510737.2
UniGeneiMm.464262

3D structure databases

ProteinModelPortaliJ3QM92
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiJ3QM92
PhosphoSitePlusiJ3QM92

Proteomic databases

PaxDbiJ3QM92
PRIDEiJ3QM92

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000179751; ENSMUSP00000136181; ENSMUSG00000095654
GeneIDi100504689
KEGGimmu:100504689
UCSCiuc012gyj.1 mouse

Organism-specific databases

CTDi389158
MGIiMGI:3779462 Plscr5

Phylogenomic databases

eggNOGiKOG0621 Eukaryota
ENOG410XSYS LUCA
GeneTreeiENSGT00390000002884
InParanoidiJ3QM92
OMAiGYVAQKW
OrthoDBiEOG091G0CUL
TreeFamiTF314939

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000095654 Expressed in 11 organ(s), highest expression level in heart

Family and domain databases

InterProiView protein in InterPro
IPR005552 Scramblase
IPR025659 Tubby-like_C
PANTHERiPTHR23248 PTHR23248, 1 hit
PfamiView protein in Pfam
PF03803 Scramblase, 1 hit
SUPFAMiSSF54518 SSF54518, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3QM92_MOUSE
AccessioniPrimary (citable) accession number: J3QM92
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: November 7, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again