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Protein
Submitted name:

Nucleolar complex protein 2 homolog

Gene

Noc2l

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-6804756 Regulation of TP53 Activity through Phosphorylation

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleolar complex protein 2 homologImported
Gene namesi
Name:Noc2lImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1931051 Noc2l

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiJ3QK52
PeptideAtlasiJ3QK52
PRIDEiJ3QK52

Expressioni

Gene expression databases

BgeeiENSMUSG00000095567 Expressed in 264 organ(s), highest expression level in ear
ExpressionAtlasiJ3QK52 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili654 – 674Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2256 Eukaryota
COG5604 LUCA
GeneTreeiENSGT00390000010057
KOiK14833
OMAiLPGINFM
OrthoDBiEOG091G04LC
TreeFamiTF314829

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR005343 Noc2
PANTHERiPTHR12687 PTHR12687, 1 hit
PfamiView protein in Pfam
PF03715 Noc2, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

J3QK52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASRAPRRR LEDLSVDEFL ASGFESGSES ELEGAAEAAA EERRARGAAW
60 70 80 90 100
NRERRGARTS PGPAGRPRKG RASEHKDQLS RLKDRDPEFY KFLQENDRSL
110 120 130 140 150
LDFSDSDSSA EEEEPFHSLP DTLEEASETE EDGGEDSDAL PRGLRSKKNE
160 170 180 190 200
PVPVTLAMVE RWRQGSRHHL SPRLFHEVVQ AFRAAVATTQ GEQEAAETCR
210 220 230 240 250
FQVADSAVFN ALVTFCIRDL CGCLQKLLFG KTPKDSNRLL PSSSPLWGKL
260 270 280 290 300
RVDVKTYLSA VVQLVACLAE ATVSAAVLQH ISSLVPYYLT FPKQCRMLLK
310 320 330 340 350
RMVVLWSTGE ESLRVLAFLV LIRVCRHKKE AFLGPILKQM YIMYVRNCKF
360 370 380 390 400
TSPSTLPLIS FMQRTLTEML ALDPSVSYQH AFLYIRQLAV HLRNAMTAGK
410 420 430 440 450
KETHQSVYNW QYVHCLYLWC RVLSTLGSSE ILQPLLYPLS QIIIGCIKLL
460 470 480 490 500
PTARFYPLRM HCVRALTLLS QTIGTFIPVL PFILEIFQQV DFNRRPGRMS
510 520 530 540 550
SKPINFSVIL KLSSTNLQEK AYRDGLLEQL CDLTLEYLHS QAHSIAFPEL
560 570 580 590 600
VLPTVLQLKS FLRECKVANY CRQVRQLLEK VQENAQHIQS LRQSATFSVS
610 620 630 640 650
DQMAVDAWEK QVREEGTPLT RYYGHWKKLR DREIQLEISG KERLEDLNFP
660 670 680 690 700
EIKRRKVEDR KDEDRKELKD LFELDSSEGE DSTDFFERGV PRLPEAHQGL
710 720 730 740 750
KEDQEEEDKE EGDSDSEDGD TDTGVDLSEL WQLAQGPQDE LEDLQLSEED
Length:750
Mass (Da):85,638
Last modified:October 3, 2012 - v1
Checksum:i16CB69C1BA0D2C16
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9WV70NOC2L_MOUSE
Nucleolar complex protein 2 homolog
Noc2l Nir
747Annotation score:
Q8BHX6Q8BHX6_MOUSE
Nucleolar complex protein 2 homolog
Noc2l AF155546
593Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAA01066805 Genomic DNA No translation available.
CAAA01066806 Genomic DNA No translation available.
RefSeqiNP_067278.2, NM_021303.2
UniGeneiMm.423051
Mm.480639
Mm.486684

Genome annotation databases

EnsembliENSMUST00000179543; ENSMUSP00000137253; ENSMUSG00000095567
GeneIDi57741
KEGGimmu:57741
UCSCiuc029vbh.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAA01066805 Genomic DNA No translation available.
CAAA01066806 Genomic DNA No translation available.
RefSeqiNP_067278.2, NM_021303.2
UniGeneiMm.423051
Mm.480639
Mm.486684

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ3QK52
PeptideAtlasiJ3QK52
PRIDEiJ3QK52

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000179543; ENSMUSP00000137253; ENSMUSG00000095567
GeneIDi57741
KEGGimmu:57741
UCSCiuc029vbh.1 mouse

Organism-specific databases

CTDi26155
MGIiMGI:1931051 Noc2l

Phylogenomic databases

eggNOGiKOG2256 Eukaryota
COG5604 LUCA
GeneTreeiENSGT00390000010057
KOiK14833
OMAiLPGINFM
OrthoDBiEOG091G04LC
TreeFamiTF314829

Enzyme and pathway databases

ReactomeiR-MMU-6804756 Regulation of TP53 Activity through Phosphorylation

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000095567 Expressed in 264 organ(s), highest expression level in ear
ExpressionAtlasiJ3QK52 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR005343 Noc2
PANTHERiPTHR12687 PTHR12687, 1 hit
PfamiView protein in Pfam
PF03715 Noc2, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiJ3QK52_MOUSE
AccessioniPrimary (citable) accession number: J3QK52
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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