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Protein
Submitted name:

Cytoplasmic dynein 1 light intermediate chain 2

Gene

DYNC1LI2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cytoplasmic dynein 1 light intermediate chain 2Imported
Gene namesi
Name:DYNC1LI2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000135720.12
HGNCiHGNC:2966 DYNC1LI2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135720

PTM / Processingi

Proteomic databases

MaxQBiJ3KSD2
PeptideAtlasiJ3KSD2
PRIDEiJ3KSD2

Expressioni

Gene expression databases

BgeeiENSG00000135720 Expressed in 246 organ(s), highest expression level in brain
ExpressionAtlasiJ3KSD2 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3905 Eukaryota
ENOG410XQS4 LUCA
GeneTreeiENSGT00390000008295

Family and domain databases

InterProiView protein in InterPro
IPR008467 Dynein1_light_intermed_chain
IPR022780 Dynein_light_int_chain
PANTHERiPTHR12688 PTHR12688, 1 hit
PfamiView protein in Pfam
PF05783 DLIC, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

J3KSD2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40 
LVHDKELAAE DEQVFLMKQQ SLLAKQPATP TRASDKRLCC QMFRKNWIE
Length:49
Mass (Da):5,747
Last modified:October 3, 2012 - v1
Checksum:iEB81F92A9AE28DCE
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43237DC1L2_HUMAN
Cytoplasmic dynein 1 light intermed...
DYNC1LI2 DNCLI2, LIC2
492Annotation score:
B4E2E0B4E2E0_HUMAN
cDNA FLJ54239, highly similar to Cy...
DYNC1LI2
271Annotation score:
H3BUM4H3BUM4_HUMAN
Cytoplasmic dynein 1 light intermed...
DYNC1LI2
186Annotation score:
J3KRZ2J3KRZ2_HUMAN
Cytoplasmic dynein 1 light intermed...
DYNC1LI2
92Annotation score:
J3KRI4J3KRI4_HUMAN
Cytoplasmic dynein 1 light intermed...
DYNC1LI2
167Annotation score:
H3BU48H3BU48_HUMAN
Cytoplasmic dynein 1 light intermed...
DYNC1LI2
56Annotation score:
J3QKK5J3QKK5_HUMAN
Cytoplasmic dynein 1 light intermed...
DYNC1LI2
40Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018557 Genomic DNA No translation available.
AC044802 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000563628; ENSP00000462434; ENSG00000135720
UCSCiuc059vkd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018557 Genomic DNA No translation available.
AC044802 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ3KSD2
PeptideAtlasiJ3KSD2
PRIDEiJ3KSD2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000563628; ENSP00000462434; ENSG00000135720
UCSCiuc059vkd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000135720.12
HGNCiHGNC:2966 DYNC1LI2
OpenTargetsiENSG00000135720
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3905 Eukaryota
ENOG410XQS4 LUCA
GeneTreeiENSGT00390000008295

Miscellaneous databases

ChiTaRSiDYNC1LI2 human

Gene expression databases

BgeeiENSG00000135720 Expressed in 246 organ(s), highest expression level in brain
ExpressionAtlasiJ3KSD2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR008467 Dynein1_light_intermed_chain
IPR022780 Dynein_light_int_chain
PANTHERiPTHR12688 PTHR12688, 1 hit
PfamiView protein in Pfam
PF05783 DLIC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KSD2_HUMAN
AccessioniPrimary (citable) accession number: J3KSD2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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