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Protein
Submitted name:

COP9 signalosome complex subunit 1

Gene

GPS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
COP9 signalosome complex subunit 1Imported
Gene namesi
Name:GPS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000169727.12
HGNCiHGNC:4549 GPS1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000169727

PTM / Processingi

Proteomic databases

MaxQBiJ3KSA5
PeptideAtlasiJ3KSA5
PRIDEiJ3KSA5

Expressioni

Gene expression databases

BgeeiENSG00000169727 Expressed in 207 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiJ3KSA5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3KSA5
SMRiJ3KSA5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili115 – 135Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0686 Eukaryota
ENOG410XRXI LUCA
GeneTreeiENSGT00510000046608

Family and domain databases

InterProiView protein in InterPro
IPR033008 CSN1
IPR019585 Rpn7/CSN1
PANTHERiPTHR14145:SF2 PTHR14145:SF2, 1 hit
PfamiView protein in Pfam
PF10602 RPN7, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All

J3KSA5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQIDVDPQED PQNAPDVNYV VENPSLDLEQ YAASYSGLMR IERLQFIADH
60 70 80 90 100
CPTLRVEALK MALSFVQRTF NVDMYEEIHR KLSEATRELQ NAPDAIPESG
110 120 130 140 150
VEPPALDTAW VEATRKKALL KLEKLDTDLK NYKGNSIKES IRRGHDDLGD
160 170 180 190 200
HYLDCGDLSN ALKCYSRARD YCTSAKHVIN MCLNVIKVSV YLQNWSHVLS
210
YVSKAESTPE
Length:210
Mass (Da):23,864
Last modified:October 3, 2012 - v1
Checksum:i43A660932F695152
GO

Computationally mapped potential isoform sequencesi

There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q13098CSN1_HUMAN
COP9 signalosome complex subunit 1
GPS1 COPS1, CSN1
491Annotation score:
C9JFE4C9JFE4_HUMAN
COP9 signalosome complex subunit 1
GPS1 hCG_1987516
471Annotation score:
A0A096LP07A0A096LP07_HUMAN
COP9 signalosome complex subunit 1
GPS1
486Annotation score:
A0A096LPJ3A0A096LPJ3_HUMAN
COP9 signalosome complex subunit 1
GPS1
490Annotation score:
J3QQX0J3QQX0_HUMAN
COP9 signalosome complex subunit 1
GPS1
79Annotation score:
A8K070A8K070_HUMAN
COP9 signalosome complex subunit 1
GPS1
526Annotation score:
J3KRJ4J3KRJ4_HUMAN
COP9 signalosome complex subunit 1
GPS1
253Annotation score:
J3QLT0J3QLT0_HUMAN
COP9 signalosome complex subunit 1
GPS1
168Annotation score:
J3KTB0J3KTB0_HUMAN
COP9 signalosome complex subunit 1
GPS1
139Annotation score:
J3KRE8J3KRE8_HUMAN
COP9 signalosome complex subunit 1
GPS1
186Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei210Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135056 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000585084; ENSP00000462391; ENSG00000169727
UCSCiuc060lus.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135056 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ3KSA5
SMRiJ3KSA5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiJ3KSA5
PeptideAtlasiJ3KSA5
PRIDEiJ3KSA5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000585084; ENSP00000462391; ENSG00000169727
UCSCiuc060lus.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000169727.12
HGNCiHGNC:4549 GPS1
OpenTargetsiENSG00000169727
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0686 Eukaryota
ENOG410XRXI LUCA
GeneTreeiENSGT00510000046608

Miscellaneous databases

ChiTaRSiGPS1 human

Gene expression databases

BgeeiENSG00000169727 Expressed in 207 organ(s), highest expression level in right hemisphere of cerebellum
ExpressionAtlasiJ3KSA5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR033008 CSN1
IPR019585 Rpn7/CSN1
PANTHERiPTHR14145:SF2 PTHR14145:SF2, 1 hit
PfamiView protein in Pfam
PF10602 RPN7, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KSA5_HUMAN
AccessioniPrimary (citable) accession number: J3KSA5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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