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Protein
Submitted name:

DNA endonuclease RBBP8

Gene

RBBP8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA endonuclease RBBP8Imported
Gene namesi
Name:RBBP8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000101773.16
HGNCiHGNC:9891 RBBP8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101773

PTM / Processingi

Proteomic databases

MaxQBiJ3KSA4
PeptideAtlasiJ3KSA4

Expressioni

Gene expression databases

BgeeiENSG00000101773 Expressed in 212 organ(s), highest expression level in testis
ExpressionAtlasiJ3KSA4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3KSA4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 64CtIP_NInterPro annotationAdd BLAST45

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili28 – 48Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ39 Eukaryota
ENOG410ZSBE LUCA
GeneTreeiENSGT00530000063835

Family and domain databases

InterProiView protein in InterPro
IPR019518 CtIP_N
IPR033594 RBBP8
IPR033316 RBBP8-like
PANTHERiPTHR15107 PTHR15107, 1 hit
PTHR15107:SF4 PTHR15107:SF4, 1 hit
PfamiView protein in Pfam
PF10482 CtIP_N, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.iShow all

J3KSA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNISGSSCGS PNSADTSSDF KDLWTKLKEC HDREVQGLQV KVTKLKQERI
60
LDAQRLEEFF TKNQ
Length:64
Mass (Da):7,317
Last modified:October 3, 2012 - v1
Checksum:i83EBBCD6177AB99B
GO

Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q99708CTIP_HUMAN
DNA endonuclease RBBP8
RBBP8 CTIP
897Annotation score:
I6L8A6I6L8A6_HUMAN
DNA endonuclease RBBP8
RBBP8
902Annotation score:
F6Q6H0F6Q6H0_HUMAN
DNA endonuclease RBBP8
RBBP8
580Annotation score:
J3QLW6J3QLW6_HUMAN
DNA endonuclease RBBP8
RBBP8
205Annotation score:
J3QL93J3QL93_HUMAN
DNA endonuclease RBBP8
RBBP8
84Annotation score:
J3QL00J3QL00_HUMAN
DNA endonuclease RBBP8
RBBP8
160Annotation score:
J3QLH2J3QLH2_HUMAN
DNA endonuclease RBBP8
RBBP8
75Annotation score:
J3QSH7J3QSH7_HUMAN
DNA endonuclease RBBP8
RBBP8
324Annotation score:
J3QRM0J3QRM0_HUMAN
DNA endonuclease RBBP8
RBBP8
29Annotation score:
V9GZ40V9GZ40_HUMAN
DNA endonuclease RBBP8
RBBP8
45Annotation score:
There is more potential isoformShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei64Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090912 Genomic DNA No translation available.
AC091147 Genomic DNA No translation available.
AC106033 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000579124; ENSP00000462390; ENSG00000101773
UCSCiuc060nwc.1 human

Similar proteinsi

Entry informationi

Entry nameiJ3KSA4_HUMAN
AccessioniPrimary (citable) accession number: J3KSA4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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