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Protein
Submitted name:

Monocarboxylate transporter 6

Gene

SLC16A5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Monocarboxylate transporter 6Imported
Gene namesi
Name:SLC16A5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000170190.15
HGNCiHGNC:10926 SLC16A5

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 68HelicalSequence analysisAdd BLAST27
Transmembranei84 – 104HelicalSequence analysisAdd BLAST21
Transmembranei111 – 130HelicalSequence analysisAdd BLAST20
Transmembranei136 – 161HelicalSequence analysisAdd BLAST26
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000170190

PTM / Processingi

Proteomic databases

PRIDEiJ3KS19

Expressioni

Gene expression databases

BgeeiENSG00000170190 Expressed in 163 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiJ3KS19 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3KS19
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 203MFSInterPro annotationAdd BLAST161

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2504 Eukaryota
COG0477 LUCA
GeneTreeiENSGT00760000118926

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR030760 MCT6
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PANTHERiPTHR11360:SF21 PTHR11360:SF21, 1 hit
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

J3KS19-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGEAGEPTG HPYRAAATLA VRPWQRRQQR MPQALERADG SWAWVVLLAT
60 70 80 90 100
MVTQGLTLGF PTCIGIFFTE LQWEFQASNS ETSWFPSILT AVLHMAGPLC
110 120 130 140 150
SILVGRFGCR VTVMLGGVLA SLGMVASSFS HNLSQLYFTA GFITGLGMCF
160 170 180 190 200
SFQSSITVLG FYFVRRRVLA NALASMGVSL GITLWPLLSR YLLENLGWRG

TFL
Length:203
Mass (Da):22,224
Last modified:October 3, 2012 - v1
Checksum:i835656F19A03AEED
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O15375MOT6_HUMAN
Monocarboxylate transporter 6
SLC16A5 MCT5, MCT6
505Annotation score:
J3QL40J3QL40_HUMAN
Monocarboxylate transporter 6
SLC16A5
454Annotation score:
J3QQW5J3QQW5_HUMAN
Monocarboxylate transporter 6
SLC16A5
236Annotation score:
J3KT93J3KT93_HUMAN
Monocarboxylate transporter 6
SLC16A5
53Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei203Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC111186 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000584207; ENSP00000462267; ENSG00000170190
UCSCiuc060jsz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC111186 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ3KS19
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiJ3KS19

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000584207; ENSP00000462267; ENSG00000170190
UCSCiuc060jsz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000170190.15
HGNCiHGNC:10926 SLC16A5
OpenTargetsiENSG00000170190
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2504 Eukaryota
COG0477 LUCA
GeneTreeiENSGT00760000118926

Miscellaneous databases

ChiTaRSiSLC16A5 human

Gene expression databases

BgeeiENSG00000170190 Expressed in 163 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiJ3KS19 baseline and differential

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR030760 MCT6
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PANTHERiPTHR11360:SF21 PTHR11360:SF21, 1 hit
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KS19_HUMAN
AccessioniPrimary (citable) accession number: J3KS19
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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