UniProtKB - J3KRG2 (J3KRG2_HUMAN)
Protein
Submitted name:
Gasdermin-A
Gene
GSDMA
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Gasdermin-AImported |
Gene namesi | Name:GSDMAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000167914.10 |
HGNCi | HGNC:13311, GSDMA |
Expressioni
Gene expression databases
Bgeei | ENSG00000167914, Expressed in skin of leg and 88 other tissues |
ExpressionAtlasi | J3KRG2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 158 | GasderminInterPro annotationAdd BLAST | 156 |
Sequence similaritiesi
Belongs to the gasdermin family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00950000183140 |
HOGENOMi | CLU_144519_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR007677, Gasdermin IPR040460, Gasdermin_pore |
PANTHERi | PTHR16399, PTHR16399, 1 hit |
Pfami | View protein in Pfam PF04598, Gasdermin, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
J3KRG2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTMFENVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG
60 70 80 90 100
ARYVRTDYTL LDVLEPGSSP SDPTDTGNFG FKNMLDTRVE GDVDVPKTVK
110 120 130 140 150
VKGTAGLSQN STLEVQTLSV APKALETVQE RKLAADHPFL KEMQDQGENL
YVVMEVVE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ96QA5 | GSDMA_HUMAN | Gasdermin-A | GSDMA GSDM, GSDM1, FKSG9 | 445 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 158 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC090844 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000577447; ENSP00000461985; ENSG00000167914 |
UCSCi | uc060euy.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC090844 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | J3KRG2 |
PRIDEi | J3KRG2 |
Protocols and materials databases
Antibodypediai | 7880, 104 antibodies |
Genome annotation databases
Ensembli | ENST00000577447; ENSP00000461985; ENSG00000167914 |
UCSCi | uc060euy.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000167914.10 |
HGNCi | HGNC:13311, GSDMA |
OpenTargetsi | ENSG00000167914 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000183140 |
HOGENOMi | CLU_144519_0_0_1 |
Gene expression databases
Bgeei | ENSG00000167914, Expressed in skin of leg and 88 other tissues |
ExpressionAtlasi | J3KRG2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007677, Gasdermin IPR040460, Gasdermin_pore |
PANTHERi | PTHR16399, PTHR16399, 1 hit |
Pfami | View protein in Pfam PF04598, Gasdermin, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | J3KRG2_HUMAN | |
Accessioni | J3KRG2Primary (citable) accession number: J3KRG2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2012 |
Last sequence update: | October 5, 2016 | |
Last modified: | August 12, 2020 | |
This is version 48 of the entry and version 8 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |