GSDMA

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Gasdermin-AImported
Gene namesⁱ	Name:GSDMAImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 17

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000167914.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13311 GSDMA

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000167914

OpenTargetsⁱ

ENSG00000167914

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	J3KRG2
PRIDEⁱ	J3KRG2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000167914 Expressed in 65 organ(s), highest expression level in skin of leg
ExpressionAtlasⁱ	J3KRG2 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	J3KRG2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	ENOG410IH8H Eukaryota ENOG41116WI LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063218

Family and domain databases

InterProⁱ	View protein in InterPro IPR007677 Gasdermin
PANTHERⁱ	PTHR16399 PTHR16399, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04598 Gasdermin, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

J3KRG2-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MTMFENVTRA LARQLNPRGD LTPLDSLIDF KRFHPFCLVL RKRKSTLFWG 
        60         70         80         90        100
ARYVRTDYTL LDVLEPGSSP SDPTDTGNFG FKNMLDTRVE GDVDVPKTVK 
       110        120        130        140        150
VKGTAGLSQN STLEVQTLSV APKALETVQE RKLAADHPFL KEMQDQGENL 

YVVMEVVE

Length:158

Mass (Da):17,791

Last modified:October 5, 2016 - v8

Checksum:ⁱA85DB97928EE2C1C

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	Q96QA5	GSDMA_HUMAN		Gasdermin-A Gasdermin-A (Gasdermin-1)	GSDMA GSDM, GSDM1, FKSG9	445	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	158	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC090844 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC090844 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000577447; ENSP00000461985; ENSG00000167914
UCSC genome browser More...UCSCⁱ	uc060euy.1 human

Protein	Similar proteins		Species	Score	Length	Source
J3KRG2	Gasdermin-A		HUMAN		445	UniRef100_Q96QA5
UPI0005D0339C		HUMAN		303

Protein	Similar proteins		Species	Score	Length	Source
J3KRG2	Gasdermin-A		HUMAN		445	UniRef90_Q96QA5
Uncharacterized protein		CALJA		446
Uncharacterized protein		Cebus capucinus imitator		446
Gasdermin A		RHIBE		445
Gasdermin A		MACFA		445
+27

Protein	Similar proteins		Species	Score	Length	Source
J3KRG2	Gasdermin-A		HUMAN		445	UniRef50_Q96QA5
Gasdermin-A		MOUSE		446
Uncharacterized protein		Cebus capucinus imitator		446
Uncharacterized protein		CALJA		446
GSDMA isoform 1		PONAB		445
+165

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC090844 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC090844 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	J3KRG2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlasⁱ	J3KRG2
PRIDEⁱ	J3KRG2

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000577447; ENSP00000461985; ENSG00000167914
UCSCⁱ	uc060euy.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000167914.10
HGNCⁱ	HGNC:13311 GSDMA
OpenTargetsⁱ	ENSG00000167914
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IH8H Eukaryota ENOG41116WI LUCA
GeneTreeⁱ	ENSGT00530000063218

Gene expression databases

Bgeeⁱ	ENSG00000167914 Expressed in 65 organ(s), highest expression level in skin of leg
ExpressionAtlasⁱ	J3KRG2 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR007677 Gasdermin
PANTHERⁱ	PTHR16399 PTHR16399, 1 hit
Pfamⁱ	View protein in Pfam PF04598 Gasdermin, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	J3KRG2_HUMAN
Accessionⁱ	J3KRG2Primary (citable) accession number: J3KRG2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 3, 2012
	Last sequence update:	October 5, 2016
	Last modified:	September 12, 2018
	This is version 38 of the entry and version 8 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - J3KRG2 (J3KRG2_HUMAN)

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Gasdermin-A

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Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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UniRef

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Supporting data

UniProtKB - J3KRG2 (J3KRG2_HUMAN)

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Gasdermin-A

GSDMA

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

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Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

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Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ