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Protein
Submitted name:

Clathrin heavy chain 1

Gene

CLTC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Clathrin heavy chain 1Imported
Gene namesi
Name:CLTCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000141367.11
HGNCiHGNC:2092 CLTC

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141367

PTM / Processingi

Proteomic databases

MaxQBiJ3KRF5
PeptideAtlasiJ3KRF5
PRIDEiJ3KRF5

Expressioni

Gene expression databases

BgeeiENSG00000141367 Expressed in 240 organ(s), highest expression level in dorsolateral prefrontal cortex
ExpressionAtlasiJ3KRF5 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiJ3KRF5, 1 interactor
MINTiJ3KRF5

Structurei

3D structure databases

ProteinModelPortaliJ3KRF5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1 – 68CHCRPROSITE-ProRule annotationAdd BLAST68

Phylogenomic databases

GeneTreeiENSGT00400000022107

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR000547 Clathrin_H-chain/VPS_repeat
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF00637 Clathrin, 1 hit
PROSITEiView protein in PROSITE
PS50236 CHCR, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

J3KRF5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XEKHELIEFR RIAAYLFKGN NRWKQSVELC KKDSLYKDAM QYASESKDTE
60 70 80 90 100
LAEELLQWFL QEEKRECFGA CLFTCYDLLR PDVVLETAWR HNIMDFAMPY
110 120 130
FIQVMKEYLT KVDAIKEKVK VDSLTSLSLE D
Length:131
Mass (Da):15,601
Last modified:October 3, 2012 - v1
Checksum:i4E06F2FCDB0ABAF4
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q00610CLH1_HUMAN
Clathrin heavy chain 1
CLTC CLH17, CLTCL2, KIAA0034
1,675Annotation score:
A0A087WVQ6A0A087WVQ6_HUMAN
Clathrin heavy chain
CLTC hCG_1818599
1,679Annotation score:
J3KS13J3KS13_HUMAN
Clathrin heavy chain 1
CLTC
612Annotation score:
K7EJJ5K7EJJ5_HUMAN
Clathrin heavy chain 1
CLTC
222Annotation score:
J3KSQ2J3KSQ2_HUMAN
Clathrin heavy chain 1
CLTC
122Annotation score:
J3QL20J3QL20_HUMAN
Clathrin heavy chain 1
CLTC
97Annotation score:
J3KTN1J3KTN1_HUMAN
Clathrin heavy chain 1
CLTC
24Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091271 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000475458; ENSP00000461977; ENSG00000141367
UCSCiuc060idk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091271 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliJ3KRF5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiJ3KRF5, 1 interactor
MINTiJ3KRF5

Proteomic databases

MaxQBiJ3KRF5
PeptideAtlasiJ3KRF5
PRIDEiJ3KRF5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000475458; ENSP00000461977; ENSG00000141367
UCSCiuc060idk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000141367.11
HGNCiHGNC:2092 CLTC
OpenTargetsiENSG00000141367
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00400000022107

Miscellaneous databases

ChiTaRSiCLTC human

Gene expression databases

BgeeiENSG00000141367 Expressed in 240 organ(s), highest expression level in dorsolateral prefrontal cortex
ExpressionAtlasiJ3KRF5 baseline and differential

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR000547 Clathrin_H-chain/VPS_repeat
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF00637 Clathrin, 1 hit
PROSITEiView protein in PROSITE
PS50236 CHCR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KRF5_HUMAN
AccessioniPrimary (citable) accession number: J3KRF5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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