UniProtKB - J3KQ34 (J3KQ34_HUMAN)
Protein
Submitted name:
COP9 signalosome complex subunit 7b
Gene
COPS7B
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: COP9 signalosome complex subunit 7bImported |
Gene namesi | Name:COPS7BImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000144524.17 |
HGNCi | HGNC:16760, COPS7B |
Subcellular locationi
Nucleus
- COP9 signalosome Source: InterPro
- nucleoplasm Source: HPA
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmARBA annotation, NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000144524, Expressed in pituitary gland and 212 other tissues |
ExpressionAtlasi | J3KQ34, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 125 | PCIInterPro annotationAdd BLAST | 125 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 189 – 230 | DisorderedSequence analysisAdd BLAST | 42 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 154 – 185 | Sequence analysisAdd BLAST | 32 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 202 – 218 | PolyampholyteSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000157155 |
Family and domain databases
InterProi | View protein in InterPro IPR041481, CSN7_helixI IPR027530, Csn7b IPR000717, PCI_dom |
PANTHERi | PTHR15350:SF8, PTHR15350:SF8, 1 hit |
Pfami | View protein in Pfam PF18392, CSN7a_helixI, 1 hit PF01399, PCI, 1 hit |
SMARTi | View protein in SMART SM00088, PINT, 1 hit |
PROSITEi | View protein in PROSITE PS50250, PCI, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All
J3KQ34-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTARRELTSV YMELRHLQIM LAEGANAAYL QLLNLFAYGT YPDYIANKES
60 70 80 90 100
LPELSTAQQN KLKHLTIVSL ASRMKCIPYS VLLKDLEMRN LRELEDLIIE
110 120 130 140 150
AVYTDIIQGK LDQRNQLLEV DFCIGRDIRK KDINNIVKTL HEWCDGCEAV
160 170 180 190 200
LLGIEQQVLR ANQYKENHNR TQQQVEAEVT NIKKTLKATA SSSAQEMEQQ
210 220 230
LAERECPPHA EQRQPTKKMS KVKGLVSSRH
Computationally mapped potential isoform sequencesi
There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9H9Q2 | CSN7B_HUMAN | COP9 signalosome complex subunit 7b | COPS7B CSN7B | 264 | Annotation score: | ||
A0A087X1P5 | A0A087X1P5_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 209 | Annotation score: | ||
J3QT73 | J3QT73_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 172 | Annotation score: | ||
J3KQ41 | J3KQ41_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 278 | Annotation score: | ||
J3QT95 | J3QT95_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 150 | Annotation score: | ||
J3QT50 | J3QT50_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 78 | Annotation score: | ||
J3QT43 | J3QT43_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 103 | Annotation score: | ||
J3QT67 | J3QT67_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 62 | Annotation score: | ||
J3QT69 | J3QT69_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 68 | Annotation score: | ||
J3QT65 | J3QT65_HUMAN | COP9 signalosome complex subunit 7b | COPS7B | 49 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC073476 Genomic DNA No translation available. |
RefSeqi | NP_001269878.1, NM_001282949.2 |
Genome annotation databases
Ensembli | ENST00000409295; ENSP00000386438; ENSG00000144524 |
GeneIDi | 64708 |
UCSCi | uc010fxy.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC073476 Genomic DNA No translation available. |
RefSeqi | NP_001269878.1, NM_001282949.2 |
3D structure databases
SMRi | J3KQ34 |
ModBasei | Search... |
Proteomic databases
MaxQBi | J3KQ34 |
PeptideAtlasi | J3KQ34 |
PRIDEi | J3KQ34 |
Protocols and materials databases
Antibodypediai | 20213, 94 antibodies |
Genome annotation databases
Ensembli | ENST00000409295; ENSP00000386438; ENSG00000144524 |
GeneIDi | 64708 |
UCSCi | uc010fxy.3, human |
Organism-specific databases
CTDi | 64708 |
EuPathDBi | HostDB:ENSG00000144524.17 |
HGNCi | HGNC:16760, COPS7B |
OpenTargetsi | ENSG00000144524 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157155 |
Miscellaneous databases
BioGRID-ORCSi | 64708, 6 hits in 848 CRISPR screens |
ChiTaRSi | COPS7B, human |
GenomeRNAii | 64708 |
Gene expression databases
Bgeei | ENSG00000144524, Expressed in pituitary gland and 212 other tissues |
ExpressionAtlasi | J3KQ34, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR041481, CSN7_helixI IPR027530, Csn7b IPR000717, PCI_dom |
PANTHERi | PTHR15350:SF8, PTHR15350:SF8, 1 hit |
Pfami | View protein in Pfam PF18392, CSN7a_helixI, 1 hit PF01399, PCI, 1 hit |
SMARTi | View protein in SMART SM00088, PINT, 1 hit |
PROSITEi | View protein in PROSITE PS50250, PCI, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | J3KQ34_HUMAN | |
Accessioni | J3KQ34Primary (citable) accession number: J3KQ34 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2012 |
Last sequence update: | October 3, 2012 | |
Last modified: | December 2, 2020 | |
This is version 67 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |