Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Anthrax toxin receptor

Gene

ANTXR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi41Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionReceptorUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Anthrax toxin receptorUniRule annotation
Gene namesi
Name:ANTXR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000163297.16
HGNCiHGNC:21732 ANTXR2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei242 – 264HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163297

PTM / Processingi

Proteomic databases

EPDiJ3KPY9
MaxQBiJ3KPY9
PeptideAtlasiJ3KPY9
PRIDEiJ3KPY9

Expressioni

Gene expression databases

BgeeiENSG00000163297 Expressed in 192 organ(s), highest expression level in layer of synovial tissue
ExpressionAtlasiJ3KPY9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3KPY9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 136VWFAInterPro annotationAdd BLAST136

Sequence similaritiesi

Belongs to the ATR family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK1W Eukaryota
ENOG410YC57 LUCA
GeneTreeiENSGT00430000031214

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR017360 Anthrax_toxin_rcpt
IPR008399 Anthrax_toxin_rcpt_C
IPR008400 Anthrax_toxin_rcpt_extracel
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF05586 Ant_C, 1 hit
PF05587 Anth_Ig, 1 hit
PF00092 VWA, 1 hit
PIRSFiPIRSF038023 Anthrax_toxin_receptor_2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD377005 Anthrax_toxin_rcpt_C, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

J3KPY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLSFIVFSS QATIILPLTG DRGKISKGLE DLKRVSPVGE TYIHEGLKLA
60 70 80 90 100
NEQIQKAGGL KTSSIIIALT DGKLDGLVPS YAEKEAKISR SLGASVYCVG
110 120 130 140 150
VLDFEQAQLE RIADSKEQVF PVKGGFQALK GIINSILAQS CTEILELQPS
160 170 180 190 200
SVCVGEEFQI VLSGRGFMLG SRNGSVLCTY TVNETYTTSV KPVSVQLNSM
210 220 230 240 250
LCPAPILNKA GETLDVSVSF NGGKSVISGS LIVTATECSN GIAAIIVILV
260 270 280 290 300
LLLLLGIGLM WWFWPLCCKV VIKDPPPPPA PAPKEEEEEP LPTKKWPTVD
310 320 330 340 350
ASYYGGRGVG GIKRMEVRWG DKGSTEEGAR LEKAKNAVVK IPEETEEPIR
360 370 380 390 400
PRPPRPKPTH QPPQTKWYTP IKGRLDALWA LLRRQYDRVS LMRPQEGDEG
410
RCINFSRVPS Q
Length:411
Mass (Da):44,841
Last modified:October 3, 2012 - v1
Checksum:i34CBF9CB86CA4571
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P58335ANTR2_HUMAN
Anthrax toxin receptor 2
ANTXR2 CMG2
489Annotation score:
A0A0C4DG84A0A0C4DG84_HUMAN
Anthrax toxin receptor 2, isoform C...
ANTXR2 hCG_1818780
245Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097711 Genomic DNA No translation available.
AC109518 Genomic DNA No translation available.
AC114773 Genomic DNA No translation available.
RefSeqiNP_001273709.1, NM_001286780.1
NP_001273710.1, NM_001286781.1
UniGeneiHs.162963

Genome annotation databases

EnsembliENST00000404191; ENSP00000384028; ENSG00000163297
GeneIDi118429
UCSCiuc032tnm.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097711 Genomic DNA No translation available.
AC109518 Genomic DNA No translation available.
AC114773 Genomic DNA No translation available.
RefSeqiNP_001273709.1, NM_001286780.1
NP_001273710.1, NM_001286781.1
UniGeneiHs.162963

3D structure databases

ProteinModelPortaliJ3KPY9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiJ3KPY9
MaxQBiJ3KPY9
PeptideAtlasiJ3KPY9
PRIDEiJ3KPY9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000404191; ENSP00000384028; ENSG00000163297
GeneIDi118429
UCSCiuc032tnm.2 human

Organism-specific databases

CTDi118429
EuPathDBiHostDB:ENSG00000163297.16
HGNCiHGNC:21732 ANTXR2
OpenTargetsiENSG00000163297
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IK1W Eukaryota
ENOG410YC57 LUCA
GeneTreeiENSGT00430000031214

Miscellaneous databases

ChiTaRSiANTXR2 human
GenomeRNAii118429

Gene expression databases

BgeeiENSG00000163297 Expressed in 192 organ(s), highest expression level in layer of synovial tissue
ExpressionAtlasiJ3KPY9 baseline and differential

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR017360 Anthrax_toxin_rcpt
IPR008399 Anthrax_toxin_rcpt_C
IPR008400 Anthrax_toxin_rcpt_extracel
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF05586 Ant_C, 1 hit
PF05587 Anth_Ig, 1 hit
PF00092 VWA, 1 hit
PIRSFiPIRSF038023 Anthrax_toxin_receptor_2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD377005 Anthrax_toxin_rcpt_C, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KPY9_HUMAN
AccessioniPrimary (citable) accession number: J3KPY9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again