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Protein
Submitted name:

Sperm-egg fusion protein Juno

Gene

IZUMO1R

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Sperm-egg fusion protein JunoImported
Gene namesi
Name:IZUMO1RImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000183560.8
HGNCiHGNC:32565 IZUMO1R

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183560

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500841903820 – 250Sequence analysisAdd BLAST231

Proteomic databases

PRIDEiJ3KNP7

Expressioni

Gene expression databases

BgeeiENSG00000183560 Expressed in 33 organ(s), highest expression level in lymph node
ExpressionAtlasiJ3KNP7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliJ3KNP7
SMRiJ3KNP7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 208Folate_recInterPro annotationAdd BLAST183

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFFP Eukaryota
ENOG4111IU4 LUCA
GeneTreeiENSGT00390000010470
KOiK13649
OMAiFPHYFPT
PhylomeDBiJ3KNP7

Family and domain databases

InterProiView protein in InterPro
IPR004269 Folate_rcpt
IPR018143 Folate_rcpt-like
PANTHERiPTHR10517 PTHR10517, 1 hit
PfamiView protein in Pfam
PF03024 Folate_rec, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

J3KNP7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MACWWPLLLE LWTVMPTWAG DELLNICMNA KHHKRVPSPE DKLYEECIPW
60 70 80 90 100
KDNACCTLTT SWEAHLDVSP LYNFSLFHCG LLMPGCRKHF IQAICFYECS
110 120 130 140 150
PNLGPWIQPV GSLGWEVAPS GQGERVVNVP LCQEDCEEWW EDCRMSYTCK
160 170 180 190 200
SNWRGGWDWS QGKNRCPKGA QCLPFSHYFP TPADLCEKTW SNSFKASPER
210 220 230 240 250
RNSGRCLQKW FEPAQGNPNV AVARLFASSA PSWELSYTIM VCSLFLPFLS
Length:250
Mass (Da):28,672
Last modified:October 5, 2016 - v8
Checksum:iCBF2FD967ABAF6E7
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6ND01JUNO_HUMAN
Sperm-egg fusion protein Juno
IZUMO1R FOLR4, JUNO
250Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002784 Genomic DNA No translation available.
RefSeqiNP_001186135.1, NM_001199206.1
UniGeneiHs.553758

Genome annotation databases

EnsembliENST00000328458; ENSP00000332963; ENSG00000183560
GeneIDi390243
KEGGihsa:390243
UCSCiuc058gov.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002784 Genomic DNA No translation available.
RefSeqiNP_001186135.1, NM_001199206.1
UniGeneiHs.553758

3D structure databases

ProteinModelPortaliJ3KNP7
SMRiJ3KNP7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiJ3KNP7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000328458; ENSP00000332963; ENSG00000183560
GeneIDi390243
KEGGihsa:390243
UCSCiuc058gov.1 human

Organism-specific databases

CTDi390243
EuPathDBiHostDB:ENSG00000183560.8
HGNCiHGNC:32565 IZUMO1R
OpenTargetsiENSG00000183560
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFFP Eukaryota
ENOG4111IU4 LUCA
GeneTreeiENSGT00390000010470
KOiK13649
OMAiFPHYFPT
PhylomeDBiJ3KNP7

Gene expression databases

BgeeiENSG00000183560 Expressed in 33 organ(s), highest expression level in lymph node
ExpressionAtlasiJ3KNP7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR004269 Folate_rcpt
IPR018143 Folate_rcpt-like
PANTHERiPTHR10517 PTHR10517, 1 hit
PfamiView protein in Pfam
PF03024 Folate_rec, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiJ3KNP7_HUMAN
AccessioniPrimary (citable) accession number: J3KNP7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 5, 2016
Last modified: November 7, 2018
This is version 42 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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