UniProtKB - J3KMX1 (J3KMX1_HUMAN)
Protein
Submitted name:
Nuclear pore complex protein Nup88
Gene
NUP88
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- structural constituent of nuclear pore Source: InterPro
GO - Biological processi
- mRNA transport Source: UniProtKB-KW
- ribosomal large subunit export from nucleus Source: InterPro
- ribosomal small subunit export from nucleus Source: InterPro
Keywordsi
Biological process | mRNA transport, Protein transport, Translocation, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: Nuclear pore complex protein Nup88Imported |
Gene namesi | Name:NUP88Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000108559.11 |
HGNCi | HGNC:8067, NUP88 |
Subcellular locationi
Nucleus
- nuclear pore complex ARBA annotation
Nucleus
- nuclear pore Source: UniProtKB-SubCell
- nucleoplasm Source: HPA
Keywords - Cellular componenti
Nuclear pore complexARBA annotation, NucleusExpressioni
Gene expression databases
Bgeei | ENSG00000108559, Expressed in testis and 231 other tissues |
ExpressionAtlasi | J3KMX1, baseline and differential |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 567 – 601 | Sequence analysisAdd BLAST | 35 |
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000015063 |
HOGENOMi | CLU_017144_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR019321, Nucleoporin_Nup88 IPR037700, NUP88/NUP82 |
PANTHERi | PTHR13257, PTHR13257, 1 hit |
Pfami | View protein in Pfam PF10168, Nup88, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
J3KMX1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XGLGGELFLW DGEDSSFLVV RLRGPSGGGE EPALSQYQRL LCINPPLFEI
60 70 80 90 100
YQVLLSPTQH HVALIGIKGL MVLELPKRWG KNSEFEGGKS TVNCSTTPVA
110 120 130 140 150
ERFFTSSTSL TLKHAAWYPS EILDPHVVLL TSDNVIRIYS LREPQTPTNV
160 170 180 190 200
IILSEAEEES LVLNKGRAYT ASLGETAVAF DFGPLAAVPK TLFGQNGKDE
210 220 230 240 250
VVAYPLYILY ENGETFLTYI SLLHSPGNIG KLLGPLPMHP AAEDNYGYDA
260 270 280 290 300
CAVLCLPCVP NILVIATESG MLYHCVVLEG EEEDDHTSEK SWDSRIDLIP
310 320 330 340 350
SLYVFECVEL ELALKLASGE DDPFDSDFSC PVKLHRDPKC PSRYHCTHEA
360 370 380 390 400
GVHSVGLTWI HKLHKFLGSD EEDKDSLQEL STEQKCFVEH ILCTKPLPCR
410 420 430 440 450
QPAPIRGFWI VPDILGPTMI CITSTYECLI WPLLSTVHPA SPPLLCTRED
460 470 480 490 500
VEVAESPLRV LAETPDSFEK HIRSILQRSV ANPAFLNCFT QLRKIKVETL
510 520 530 540 550
FLRASEKDIA PPPEECLQLL SRATQVFREQ YILKQDLAKE EIQRRVKLLC
560 570 580 590 600
DQKKKQLEDL SYCREERKSL REMAERLADK YEEAKEKQED IMNRMKKLLH
610 620 630 640 650
SFHSELPVLS DSERDMKKEL QLIPDQLRHL GNAIKQVTMK KDYQQQKMEK
660 670 680 690
VLSLPKPTII LSAYQRKCIQ SILKEEGEHI REMVKQINDI RNHVNF
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ99567 | NUP88_HUMAN | Nuclear pore complex protein Nup88 | NUP88 | 741 | Annotation score: | ||
I3L4K7 | I3L4K7_HUMAN | Nuclear pore complex protein Nup88 | NUP88 | 110 | Annotation score: | ||
I3L245 | I3L245_HUMAN | Nuclear pore complex protein Nup88 | NUP88 | 153 | Annotation score: | ||
I3L2W3 | I3L2W3_HUMAN | Nuclear pore complex protein Nup88 | NUP88 | 128 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC004148 Genomic DNA No translation available. AC015727 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000225696; ENSP00000225696; ENSG00000108559 |
UCSCi | uc060aat.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC004148 Genomic DNA No translation available. AC015727 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
MaxQBi | J3KMX1 |
PeptideAtlasi | J3KMX1 |
PRIDEi | J3KMX1 |
Protocols and materials databases
Antibodypediai | 3693, 189 antibodies |
Genome annotation databases
Ensembli | ENST00000225696; ENSP00000225696; ENSG00000108559 |
UCSCi | uc060aat.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000108559.11 |
HGNCi | HGNC:8067, NUP88 |
OpenTargetsi | ENSG00000108559 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000015063 |
HOGENOMi | CLU_017144_0_0_1 |
Miscellaneous databases
ChiTaRSi | NUP88, human |
Gene expression databases
Bgeei | ENSG00000108559, Expressed in testis and 231 other tissues |
ExpressionAtlasi | J3KMX1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR019321, Nucleoporin_Nup88 IPR037700, NUP88/NUP82 |
PANTHERi | PTHR13257, PTHR13257, 1 hit |
Pfami | View protein in Pfam PF10168, Nup88, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | J3KMX1_HUMAN | |
Accessioni | J3KMX1Primary (citable) accession number: J3KMX1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2012 |
Last sequence update: | October 3, 2012 | |
Last modified: | October 7, 2020 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |