Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tafazzin family protein

Gene

Taz

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Some isoforms may be involved in cardiolipin metabolism.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1482798 Acyl chain remodeling of CL

Names & Taxonomyi

Protein namesi
Recommended name:
Tafazzin family proteinUniRule annotation
Gene namesi
Name:TazImported
Synonyms:TAZUniRule annotation
ORF Names:RP23-436K3.6-015Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:109626 Taz

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 34HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000009995 Expressed in 277 organ(s), highest expression level in zone of skin

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109818

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 188PlsCInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the taffazin family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2847 Eukaryota
ENOG410XT5T LUCA
GeneTreeiENSGT00390000018621
KOiK13511
OMAiKGEWVHI
OrthoDBiEOG091G0DPL
TreeFamiTF313862

Family and domain databases

InterProiView protein in InterPro
IPR002123 Plipid/glycerol_acylTrfase
IPR000872 Tafazzin
PANTHERiPTHR12497 PTHR12497, 1 hit
PfamiView protein in Pfam
PF01553 Acyltransferase, 1 hit
PRINTSiPR00979 TAFAZZIN
SMARTiView protein in SMART
SM00563 PlsC, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

I7HJS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLHVKWPFP AVPRLTWTLA SSVVMGLVGT YSCFWTKYMN HLTVHNKEVL
60 70 80 90 100
YELIENRGPA TPLITVSNHQ SCMDDPHLWG ILKLRHIWNL KLMRWTPAAA
110 120 130 140 150
DICFTKELHS HFFSLGKCVP VCRGDGVYQK GMDFILEKLN HGDWVHIFPE
160 170 180 190 200
GKVNMSSEFL RFKWVGIGRL IAECHLNPII LPLWHVGMND VLPNSPPYFP
210 220 230 240 250
RFGQKITVLI GKPFSTLPVL ERLRAENKSA VEMRKALTDF IQEEFQRLKM
260
QAEQLHNHFQ PGR
Length:263
Mass (Da):30,433
Last modified:October 3, 2012 - v1
Checksum:i2B8FF7A1341D3888
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q810E8Q810E8_MOUSE
Tafazzin family protein
Taz TAZ
201Annotation score:
H3BK99H3BK99_MOUSE
Tafazzin family protein
Taz TAZ
175Annotation score:
Q91WF0Q91WF0_MOUSE
Tafazzin family protein
Taz TAZ, mCG_129905, RP23-436K3.6-001
262Annotation score:
J3JS92J3JS92_MOUSE
Tafazzin family protein
Taz TAZ, RP23-436K3.6-020
248Annotation score:
H3BKZ8H3BKZ8_MOUSE
Tafazzin family protein
Taz TAZ
178Annotation score:
H3BJJ8H3BJJ8_MOUSE
Tafazzin family protein
Taz TAZ
148Annotation score:
F6TQ32F6TQ32_MOUSE
Tafazzin family protein
Taz TAZ
64Annotation score:
B7FAU2B7FAU2_MOUSE
Tafazzin family protein
Taz TAZ, RP23-436K3.6-007
134Annotation score:
F6V7B7F6V7B7_MOUSE
Tafazzin
Taz
21Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807376 Genomic DNA Translation: CAM24341.1
RefSeqiNP_001167018.1, NM_001173547.2
XP_006528307.1, XM_006528244.2
UniGeneiMm.268483

Genome annotation databases

EnsembliENSMUST00000114180; ENSMUSP00000109818; ENSMUSG00000009995
GeneIDi66826
KEGGimmu:66826
UCSCiuc009toh.3 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807376 Genomic DNA Translation: CAM24341.1
RefSeqiNP_001167018.1, NM_001173547.2
XP_006528307.1, XM_006528244.2
UniGeneiMm.268483

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109818

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000114180; ENSMUSP00000109818; ENSMUSG00000009995
GeneIDi66826
KEGGimmu:66826
UCSCiuc009toh.3 mouse

Organism-specific databases

CTDi6901
MGIiMGI:109626 Taz

Phylogenomic databases

eggNOGiKOG2847 Eukaryota
ENOG410XT5T LUCA
GeneTreeiENSGT00390000018621
KOiK13511
OMAiKGEWVHI
OrthoDBiEOG091G0DPL
TreeFamiTF313862

Enzyme and pathway databases

ReactomeiR-MMU-1482798 Acyl chain remodeling of CL

Miscellaneous databases

ChiTaRSiTaz mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000009995 Expressed in 277 organ(s), highest expression level in zone of skin

Family and domain databases

InterProiView protein in InterPro
IPR002123 Plipid/glycerol_acylTrfase
IPR000872 Tafazzin
PANTHERiPTHR12497 PTHR12497, 1 hit
PfamiView protein in Pfam
PF01553 Acyltransferase, 1 hit
PRINTSiPR00979 TAFAZZIN
SMARTiView protein in SMART
SM00563 PlsC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI7HJS2_MOUSE
AccessioniPrimary (citable) accession number: I7HJS2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2012
Last sequence update: October 3, 2012
Last modified: November 7, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again