Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Macrophage migration inhibitory factor

Gene

MIF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Macrophage migration inhibitory factorImported
Gene namesi
Name:MIFImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000240972.1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000240972 Expressed in 89 organ(s), highest expression level in left adrenal gland

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
WDYHV1Q96HA83EBI-10287234,EBI-741158

GO - Molecular functioni

Protein-protein interaction databases

IntActiI4AY87, 1 interactor
I4AY87, 1 interactor

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1759 Eukaryota
ENOG41122MF LUCA
KOiK07253
OMAiPDRIYIN
OrthoDBiEOG091G0ZNJ

Family and domain databases

Gene3Di3.30.429.10, 1 hit
InterProiView protein in InterPro
IPR001398 Macrophage_inhib_fac
IPR019829 Macrophage_inhib_fac_CS
IPR014347 Tautomerase/MIF_sf
PANTHERiPTHR11954 PTHR11954, 1 hit
PfamiView protein in Pfam
PF01187 MIF, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004816 Macrophage_inhib_fac, 1 hit
SUPFAMiSSF55331 SSF55331, 1 hit
PROSITEiView protein in PROSITE
PS01158 MIF, 1 hit

Sequencei

Sequence statusi: Fragment.

I4AY87-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF
60 70 80 90 100
GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY
110
DMNAANVGWN NSTFA
Length:115
Mass (Da):12,476
Last modified:September 5, 2012 - v1
Checksum:i56D51107C05286B2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei115Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ846015 mRNA Translation: AFM09726.1
HF564790 Genomic DNA Translation: CCP37995.1
RefSeqiNP_002406.1, NM_002415.1
UniGeneiHs.407995

Genome annotation databases

GeneIDi4282
KEGGihsa:4282

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ846015 mRNA Translation: AFM09726.1
HF564790 Genomic DNA Translation: CCP37995.1
RefSeqiNP_002406.1, NM_002415.1
UniGeneiHs.407995

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiI4AY87, 1 interactor
I4AY87, 1 interactor

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4282
KEGGihsa:4282

Organism-specific databases

CTDi4282
EuPathDBiHostDB:ENSG00000240972.1

Phylogenomic databases

eggNOGiKOG1759 Eukaryota
ENOG41122MF LUCA
KOiK07253
OMAiPDRIYIN
OrthoDBiEOG091G0ZNJ

Miscellaneous databases

GenomeRNAii4282

Gene expression databases

BgeeiENSG00000240972 Expressed in 89 organ(s), highest expression level in left adrenal gland

Family and domain databases

Gene3Di3.30.429.10, 1 hit
InterProiView protein in InterPro
IPR001398 Macrophage_inhib_fac
IPR019829 Macrophage_inhib_fac_CS
IPR014347 Tautomerase/MIF_sf
PANTHERiPTHR11954 PTHR11954, 1 hit
PfamiView protein in Pfam
PF01187 MIF, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004816 Macrophage_inhib_fac, 1 hit
SUPFAMiSSF55331 SSF55331, 1 hit
PROSITEiView protein in PROSITE
PS01158 MIF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiI4AY87_HUMAN
AccessioniPrimary (citable) accession number: I4AY87
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: November 7, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again