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UniProtKB - I3ZNN6 (I3ZNN6_HUMAN)

Entry version 29 (12 Aug 2020)
Sequence version 1 (05 Sep 2012)
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Protein
Submitted name:

Fatty acid desaturase 1

Gene

FADS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Fatty acid desaturase 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FADS1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 29HelicalSequence analysisAdd BLAST18
Transmembranei35 – 57HelicalSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

I3ZNN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
ELRATVERMG LMKANHVFFL LYLLHILLLD GAAWLTLWVF GTSFLPFLLC 

AVLLSAVQ
Length:58
Mass (Da):6,577
Last modified:September 5, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC080722D22AADE6D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei58Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
JQ773200 Genomic DNA Translation: AFL91629.1
JQ773201 Genomic DNA Translation: AFL91630.1
JQ773202 Genomic DNA Translation: AFL91631.1
JQ773203 Genomic DNA Translation: AFL91632.1
JQ773204 Genomic DNA Translation: AFL91633.1
JQ773205 Genomic DNA Translation: AFL91634.1
JQ773206 Genomic DNA Translation: AFL91635.1
JQ773207 Genomic DNA Translation: AFL91636.1
JQ773208 Genomic DNA Translation: AFL91637.1
JQ773209 Genomic DNA Translation: AFL91638.1
JQ773210 Genomic DNA Translation: AFL91639.1
JQ773211 Genomic DNA Translation: AFL91640.1
JQ773212 Genomic DNA Translation: AFL91641.1
JQ773213 Genomic DNA Translation: AFL91642.1
JQ773214 Genomic DNA Translation: AFL91643.1
JQ773215 Genomic DNA Translation: AFL91644.1
JQ773216 Genomic DNA Translation: AFL91645.1
JQ773217 Genomic DNA Translation: AFL91646.1
JQ773218 Genomic DNA Translation: AFL91647.1
JQ773219 Genomic DNA Translation: AFL91648.1
JQ773220 Genomic DNA Translation: AFL91649.1
JQ773221 Genomic DNA Translation: AFL91650.1
JQ773222 Genomic DNA Translation: AFL91651.1
JQ773223 Genomic DNA Translation: AFL91652.1
JQ773224 Genomic DNA Translation: AFL91653.1
JQ773225 Genomic DNA Translation: AFL91654.1
JQ773226 Genomic DNA Translation: AFL91655.1
JQ773227 Genomic DNA Translation: AFL91656.1
JQ773228 Genomic DNA Translation: AFL91657.1
JQ773229 Genomic DNA Translation: AFL91658.1
JQ773230 Genomic DNA Translation: AFL91659.1
JQ773231 Genomic DNA Translation: AFL91660.1
JQ773232 Genomic DNA Translation: AFL91661.1
JQ773233 Genomic DNA Translation: AFL91662.1
JQ773234 Genomic DNA Translation: AFL91663.1
JQ773235 Genomic DNA Translation: AFL91664.1
JQ773236 Genomic DNA Translation: AFL91665.1
JQ773237 Genomic DNA Translation: AFL91666.1
JQ773238 Genomic DNA Translation: AFL91667.1
JQ773239 Genomic DNA Translation: AFL91668.1
JQ773240 Genomic DNA Translation: AFL91669.1
JQ773241 Genomic DNA Translation: AFL91670.1
JQ773242 Genomic DNA Translation: AFL91671.1
JQ773243 Genomic DNA Translation: AFL91672.1
JQ773244 Genomic DNA Translation: AFL91673.1
JQ773245 Genomic DNA Translation: AFL91674.1
JQ773247 Genomic DNA Translation: AFL91676.1
JQ773249 Genomic DNA Translation: AFL91678.1
JQ773250 Genomic DNA Translation: AFL91679.1
JQ773252 Genomic DNA Translation: AFL91681.1
JQ773253 Genomic DNA Translation: AFL91682.1
JQ773254 Genomic DNA Translation: AFL91683.1
JQ773255 Genomic DNA Translation: AFL91684.1
JQ773256 Genomic DNA Translation: AFL91685.1
JQ773257 Genomic DNA Translation: AFL91686.1
JQ773259 Genomic DNA Translation: AFL91688.1
JQ773260 Genomic DNA Translation: AFL91689.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ773200 Genomic DNA Translation: AFL91629.1
JQ773201 Genomic DNA Translation: AFL91630.1
JQ773202 Genomic DNA Translation: AFL91631.1
JQ773203 Genomic DNA Translation: AFL91632.1
JQ773204 Genomic DNA Translation: AFL91633.1
JQ773205 Genomic DNA Translation: AFL91634.1
JQ773206 Genomic DNA Translation: AFL91635.1
JQ773207 Genomic DNA Translation: AFL91636.1
JQ773208 Genomic DNA Translation: AFL91637.1
JQ773209 Genomic DNA Translation: AFL91638.1
JQ773210 Genomic DNA Translation: AFL91639.1
JQ773211 Genomic DNA Translation: AFL91640.1
JQ773212 Genomic DNA Translation: AFL91641.1
JQ773213 Genomic DNA Translation: AFL91642.1
JQ773214 Genomic DNA Translation: AFL91643.1
JQ773215 Genomic DNA Translation: AFL91644.1
JQ773216 Genomic DNA Translation: AFL91645.1
JQ773217 Genomic DNA Translation: AFL91646.1
JQ773218 Genomic DNA Translation: AFL91647.1
JQ773219 Genomic DNA Translation: AFL91648.1
JQ773220 Genomic DNA Translation: AFL91649.1
JQ773221 Genomic DNA Translation: AFL91650.1
JQ773222 Genomic DNA Translation: AFL91651.1
JQ773223 Genomic DNA Translation: AFL91652.1
JQ773224 Genomic DNA Translation: AFL91653.1
JQ773225 Genomic DNA Translation: AFL91654.1
JQ773226 Genomic DNA Translation: AFL91655.1
JQ773227 Genomic DNA Translation: AFL91656.1
JQ773228 Genomic DNA Translation: AFL91657.1
JQ773229 Genomic DNA Translation: AFL91658.1
JQ773230 Genomic DNA Translation: AFL91659.1
JQ773231 Genomic DNA Translation: AFL91660.1
JQ773232 Genomic DNA Translation: AFL91661.1
JQ773233 Genomic DNA Translation: AFL91662.1
JQ773234 Genomic DNA Translation: AFL91663.1
JQ773235 Genomic DNA Translation: AFL91664.1
JQ773236 Genomic DNA Translation: AFL91665.1
JQ773237 Genomic DNA Translation: AFL91666.1
JQ773238 Genomic DNA Translation: AFL91667.1
JQ773239 Genomic DNA Translation: AFL91668.1
JQ773240 Genomic DNA Translation: AFL91669.1
JQ773241 Genomic DNA Translation: AFL91670.1
JQ773242 Genomic DNA Translation: AFL91671.1
JQ773243 Genomic DNA Translation: AFL91672.1
JQ773244 Genomic DNA Translation: AFL91673.1
JQ773245 Genomic DNA Translation: AFL91674.1
JQ773247 Genomic DNA Translation: AFL91676.1
JQ773249 Genomic DNA Translation: AFL91678.1
JQ773250 Genomic DNA Translation: AFL91679.1
JQ773252 Genomic DNA Translation: AFL91681.1
JQ773253 Genomic DNA Translation: AFL91682.1
JQ773254 Genomic DNA Translation: AFL91683.1
JQ773255 Genomic DNA Translation: AFL91684.1
JQ773256 Genomic DNA Translation: AFL91685.1
JQ773257 Genomic DNA Translation: AFL91686.1
JQ773259 Genomic DNA Translation: AFL91688.1
JQ773260 Genomic DNA Translation: AFL91689.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FADS1, human

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI3ZNN6_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I3ZNN6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: August 12, 2020
This is version 29 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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