Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - I3ZNL2 (I3ZNL2_HUMAN)

Entry version 31 (12 Aug 2020)
Sequence version 1 (05 Sep 2012)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Fatty acid desaturase 1

Gene

FADS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Fatty acid desaturase 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FADS1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei12 – 35HelicalSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...PeptideAtlasi		I3ZNL2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

I3ZNL2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40
DLAWMITFYV RFFLTYVPLL GLKAFLGLFF IVRFLESNWF
Length:40
Mass (Da):4,896
Last modified:September 5, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3367C4DE3C184309
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei40Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
JQ773089 Genomic DNA Translation: AFL91575.1
JQ773090 Genomic DNA Translation: AFL91576.1
JQ773092 Genomic DNA Translation: AFL91578.1
JQ773093 Genomic DNA Translation: AFL91579.1
JQ773094 Genomic DNA Translation: AFL91580.1
JQ773095 Genomic DNA Translation: AFL91581.1
JQ773096 Genomic DNA Translation: AFL91582.1
JQ773097 Genomic DNA Translation: AFL91583.1
JQ773098 Genomic DNA Translation: AFL91584.1
JQ773099 Genomic DNA Translation: AFL91585.1
JQ773100 Genomic DNA Translation: AFL91586.1
JQ773101 Genomic DNA Translation: AFL91587.1
JQ773102 Genomic DNA Translation: AFL91588.1
JQ773103 Genomic DNA Translation: AFL91589.1
JQ773104 Genomic DNA Translation: AFL91590.1
JQ773105 Genomic DNA Translation: AFL91591.1
JQ773106 Genomic DNA Translation: AFL91592.1
JQ773107 Genomic DNA Translation: AFL91593.1
JQ773108 Genomic DNA Translation: AFL91594.1
JQ773109 Genomic DNA Translation: AFL91595.1
JQ773110 Genomic DNA Translation: AFL91596.1
JQ773111 Genomic DNA Translation: AFL91597.1
JQ773112 Genomic DNA Translation: AFL91598.1
JQ773113 Genomic DNA Translation: AFL91599.1
JQ773114 Genomic DNA Translation: AFL91600.1
JQ773115 Genomic DNA Translation: AFL91601.1
JQ773116 Genomic DNA Translation: AFL91602.1
JQ773117 Genomic DNA Translation: AFL91603.1
JQ773118 Genomic DNA Translation: AFL91604.1
JQ773119 Genomic DNA Translation: AFL91605.1
JQ773120 Genomic DNA Translation: AFL91606.1
JQ773121 Genomic DNA Translation: AFL91607.1
JQ773122 Genomic DNA Translation: AFL91608.1
JQ773123 Genomic DNA Translation: AFL91609.1
JQ773124 Genomic DNA Translation: AFL91610.1
JQ773125 Genomic DNA Translation: AFL91611.1
JQ773126 Genomic DNA Translation: AFL91612.1
JQ773127 Genomic DNA Translation: AFL91613.1
JQ773128 Genomic DNA Translation: AFL91614.1
JQ773129 Genomic DNA Translation: AFL91615.1
JQ773130 Genomic DNA Translation: AFL91616.1
JQ773131 Genomic DNA Translation: AFL91617.1
JQ773132 Genomic DNA Translation: AFL91618.1
JQ773133 Genomic DNA Translation: AFL91619.1
JQ773134 Genomic DNA Translation: AFL91620.1
JQ773135 Genomic DNA Translation: AFL91621.1
JQ773136 Genomic DNA Translation: AFL91622.1
JQ773138 Genomic DNA Translation: AFL91624.1
JQ773139 Genomic DNA Translation: AFL91625.1
JQ773140 Genomic DNA Translation: AFL91626.1
JQ773141 Genomic DNA Translation: AFL91627.1
JQ773142 Genomic DNA Translation: AFL91628.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ773089 Genomic DNA Translation: AFL91575.1
JQ773090 Genomic DNA Translation: AFL91576.1
JQ773092 Genomic DNA Translation: AFL91578.1
JQ773093 Genomic DNA Translation: AFL91579.1
JQ773094 Genomic DNA Translation: AFL91580.1
JQ773095 Genomic DNA Translation: AFL91581.1
JQ773096 Genomic DNA Translation: AFL91582.1
JQ773097 Genomic DNA Translation: AFL91583.1
JQ773098 Genomic DNA Translation: AFL91584.1
JQ773099 Genomic DNA Translation: AFL91585.1
JQ773100 Genomic DNA Translation: AFL91586.1
JQ773101 Genomic DNA Translation: AFL91587.1
JQ773102 Genomic DNA Translation: AFL91588.1
JQ773103 Genomic DNA Translation: AFL91589.1
JQ773104 Genomic DNA Translation: AFL91590.1
JQ773105 Genomic DNA Translation: AFL91591.1
JQ773106 Genomic DNA Translation: AFL91592.1
JQ773107 Genomic DNA Translation: AFL91593.1
JQ773108 Genomic DNA Translation: AFL91594.1
JQ773109 Genomic DNA Translation: AFL91595.1
JQ773110 Genomic DNA Translation: AFL91596.1
JQ773111 Genomic DNA Translation: AFL91597.1
JQ773112 Genomic DNA Translation: AFL91598.1
JQ773113 Genomic DNA Translation: AFL91599.1
JQ773114 Genomic DNA Translation: AFL91600.1
JQ773115 Genomic DNA Translation: AFL91601.1
JQ773116 Genomic DNA Translation: AFL91602.1
JQ773117 Genomic DNA Translation: AFL91603.1
JQ773118 Genomic DNA Translation: AFL91604.1
JQ773119 Genomic DNA Translation: AFL91605.1
JQ773120 Genomic DNA Translation: AFL91606.1
JQ773121 Genomic DNA Translation: AFL91607.1
JQ773122 Genomic DNA Translation: AFL91608.1
JQ773123 Genomic DNA Translation: AFL91609.1
JQ773124 Genomic DNA Translation: AFL91610.1
JQ773125 Genomic DNA Translation: AFL91611.1
JQ773126 Genomic DNA Translation: AFL91612.1
JQ773127 Genomic DNA Translation: AFL91613.1
JQ773128 Genomic DNA Translation: AFL91614.1
JQ773129 Genomic DNA Translation: AFL91615.1
JQ773130 Genomic DNA Translation: AFL91616.1
JQ773131 Genomic DNA Translation: AFL91617.1
JQ773132 Genomic DNA Translation: AFL91618.1
JQ773133 Genomic DNA Translation: AFL91619.1
JQ773134 Genomic DNA Translation: AFL91620.1
JQ773135 Genomic DNA Translation: AFL91621.1
JQ773136 Genomic DNA Translation: AFL91622.1
JQ773138 Genomic DNA Translation: AFL91624.1
JQ773139 Genomic DNA Translation: AFL91625.1
JQ773140 Genomic DNA Translation: AFL91626.1
JQ773141 Genomic DNA Translation: AFL91627.1
JQ773142 Genomic DNA Translation: AFL91628.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PeptideAtlasiI3ZNL2

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FADS1, human

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI3ZNL2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I3ZNL2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: August 12, 2020
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again