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Entry version 47 (10 Apr 2019)
Sequence version 1 (05 Sep 2012)
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Protein

Beta-xylanase

Gene

Tsac_1459

Organism
Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.UniRule annotation EC:3.2.1.8

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei599NucleophilePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradationUniRule annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
TSAC1094508:GLMA-1481-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Beta-xylanaseUniRule annotation (EC:3.2.1.8UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:Tsac_1459Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiThermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1094508 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisThermoanaerobacterium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006178 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 32Sequence analysisAdd BLAST32
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500368160833 – 1432Beta-xylanaseSequence analysisAdd BLAST1400

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
1094508.Tsac_1459

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
I3VVC1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini351 – 674GH10InterPro annotationAdd BLAST324
Domaini1248 – 1311SLHInterPro annotationAdd BLAST64
Domaini1312 – 1370SLHInterPro annotationAdd BLAST59
Domaini1373 – 1432SLHInterPro annotationAdd BLAST60

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 10 (cellulase F) family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K01181

Identification of Orthologs from Complete Genome Data

More...
OMAi
IGMQMHI

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010502 Carb-bd_dom_fam9
IPR003305 CenC_carb-bd
IPR008979 Galactose-bd-like_sf
IPR001000 GH10
IPR031158 GH10_AS
IPR018087 Glyco_hydro_5_CS
IPR017853 Glycoside_hydrolase_SF
IPR001119 SLH_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06452 CBM9_1, 2 hits
PF02018 CBM_4_9, 2 hits
PF00331 Glyco_hydro_10, 1 hit
PF00395 SLH, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00134 GLHYDRLASE10

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00633 Glyco_10, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 2 hits
SSF51445 SSF51445, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00591 GH10_1, 1 hit
PS51760 GH10_2, 1 hit
PS00659 GLYCOSYL_HYDROL_F5, 1 hit
PS51272 SLH, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

I3VVC1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSIVNRVVS IVTALIMIFG TSLFSQHIRA FADDTNTNLV SNGDFETGTI
60 70 80 90 100
DGWIKQGNPT LEVTTEQAIG QYSMKVTGRT QTYEGPAYSF LGKMQKGESY
110 120 130 140 150
NVSLKVRLVS EQNSSNPFIT VTMFREDDNG KHYDTIVWQK QVSEDSWTTV
160 170 180 190 200
SGTYTLDYTG TLKTLYMYVE SPDPTLEYYI DDVVVTPQNP IQVGNVITNG
210 220 230 240 250
TFENGNTSGW VGTGSSVVKA VYGVAHSGGY SLLTTGRTAN WNGPSYDLTG
260 270 280 290 300
KIVPGQQYNV DFWVKFVNGN DTEQIKATVK ATSDKDNYIQ VNDFANVNKG
310 320 330 340 350
EWTEIKGSFT LPVADYSGVS IYVESQNPTL EFYIDDFSVI GEISNNQITI
360 370 380 390 400
QNDIPDLYSV FKDYFPIGVA VDPSRLNDAD PHAQLTAKHF NMLVAENAMK
410 420 430 440 450
PESLQPTEGN FTFDNADKIV DYAIAHNMKM RGHTLLWHNQ VPDWFFQDPS
460 470 480 490 500
DPSKPASRDL LLQRLRTHIT TVLDHFKTKY GSQNPIIGWD VVNEVLDDNG
510 520 530 540 550
NLRNSKWLQI IGPDYIEKAF EYAHEADPSM KLFINDYNIE NNGVKTQAMY
560 570 580 590 600
DLVKKLKNEG VPINGIGMQM HISINSNIDN IKASIEKLAS LGVEIQVTEL
610 620 630 640 650
DMNMNGDVSN DALLKQARLY KQLFDLFKAE KQYITAVVFW GVSDDVSWLS
660 670 680 690 700
KPNAPLLFDS KLQAKPAYWA IVDPGKAIPD IQSAKALEGS PTIGANVDSS
710 720 730 740 750
WKLVKPLYAN TYVKGTIGAT AAVKSMWDTK NLYLLVQISD NTPSNNDGIE
760 770 780 790 800
IFVDKNDNKS TTYESDDEHY IVKRDGTGSS NITKYVMSNA DGYVAQIAIP
810 820 830 840 850
IEDISPVLND KIGFDIRIND DQGSGNVNAI TVWNDYTNSQ DTNTAYFGDL
860 870 880 890 900
VLSKPAQIAT AIYGTPVIDG KVDGVWNNAE AISTNTWVLG SNGATATAKM
910 920 930 940 950
MWDDKYLYIL ADVTDNNLNK SSVNPYEQDS VEVFVDQNND KTTYYENDDG
960 970 980 990 1000
QFRVNYDNEQ SFGGSTNSNG FKSATSLTQN GYIVEEAIPW TSITPLNGTI
1010 1020 1030 1040 1050
IGFDLQVNDA DENGKRTGIV TWCDPSGNSW QDTSGFGNLM LTGKPSWGST
1060 1070 1080 1090 1100
SNSGTTSSSS NTSSTIGVIT KNGNVITLIL DAGKAKDLIV NSKDKKVVFD
1110 1120 1130 1140 1150
ITTIGEGQQK VVQISKDILD TSAANGKDIV IKSDNASIAL TKDALNQNQI
1160 1170 1180 1190 1200
QNGVNVSIKD NGKPNVTNYV TLSNVVDITI SGSSGNVALA KPVEVTLNIS
1210 1220 1230 1240 1250
KANDPRKVAV YYYNPTTNQW EYVGGKVDAS SGTITFNATH FSQYAAFEYD
1260 1270 1280 1290 1300
KTFNDIKDNW AKDVIEVLAS RHIVEGMTDT QYEPNKTVTR AEFTAMILRL
1310 1320 1330 1340 1350
LNIKEEAYSG EFSDVKSGDW YANAIEAAYK AGIIEGDGKN ARPNDSITRE
1360 1370 1380 1390 1400
EMTAIAMRAY EMLTQYKEEN IGATTFSDDK SISDWARNVV ANAAKLGIVN
1410 1420 1430
GEPNNVFAPK GNATRAEAAA IIYGLLEKTN NL
Length:1,432
Mass (Da):157,621
Last modified:September 5, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i568C77DF3CCACEE5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP003184 Genomic DNA Translation: AFK86466.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AFK86466; AFK86466; Tsac_1459

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tsh:Tsac_1459

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1094508.3.peg.1480

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003184 Genomic DNA Translation: AFK86466.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3W24X-ray1.35A349-684[»]
3W25X-ray1.32A349-684[»]
3W26X-ray1.60A349-684[»]
3W27X-ray1.41A349-684[»]
3W28X-ray1.39A349-684[»]
3W29X-ray1.39A349-684[»]
SMRiI3VVC1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi1094508.Tsac_1459

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFK86466; AFK86466; Tsac_1459
KEGGitsh:Tsac_1459
PATRICifig|1094508.3.peg.1480

Phylogenomic databases

KOiK01181
OMAiIGMQMHI

Enzyme and pathway databases

BioCyciTSAC1094508:GLMA-1481-MONOMER

Family and domain databases

Gene3Di2.60.120.260, 2 hits
InterProiView protein in InterPro
IPR010502 Carb-bd_dom_fam9
IPR003305 CenC_carb-bd
IPR008979 Galactose-bd-like_sf
IPR001000 GH10
IPR031158 GH10_AS
IPR018087 Glyco_hydro_5_CS
IPR017853 Glycoside_hydrolase_SF
IPR001119 SLH_dom
PfamiView protein in Pfam
PF06452 CBM9_1, 2 hits
PF02018 CBM_4_9, 2 hits
PF00331 Glyco_hydro_10, 1 hit
PF00395 SLH, 3 hits
PRINTSiPR00134 GLHYDRLASE10
SMARTiView protein in SMART
SM00633 Glyco_10, 1 hit
SUPFAMiSSF49785 SSF49785, 2 hits
SSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS00591 GH10_1, 1 hit
PS51760 GH10_2, 1 hit
PS00659 GLYCOSYL_HYDROL_F5, 1 hit
PS51272 SLH, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI3VVC1_THESW
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I3VVC1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: April 10, 2019
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported
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