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UniProtKB - I3R4Y8 (I3R4Y8_HALMT)

Entry version 53 (25 May 2022)
Sequence version 1 (05 Sep 2012)
Previous versions | rss
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Protein

Dolichyl-phosphooligosaccharide-protein glycotransferase

Gene

stt3

Organism
Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • An archaeal dolichyl phosphooligosaccharide + [protein]-L-asparagine = an archaeal dolichyl phosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.ARBA annotation EC:2.4.99.21

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.ARBA annotation
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferaseImportedARBA annotation, Transferase
LigandMagnesiumARBA annotation, ManganeseARBA annotation, Metal-bindingARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00378

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Dolichyl-phosphooligosaccharide-protein glycotransferaseARBA annotation (EC:2.4.99.21ARBA annotation)
Alternative name(s):
Oligosaccharyl transferaseARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:stt3Imported
Ordered Locus Names:HFX_1592Imported
ORF Names:BM92_01155Imported, C439_02522Imported, E6P09_10990Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri523841 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Haloferacales › Haloferacaceae › Haloferax ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000011603 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000006469 Componenti: Chromosome
  • UP000027075 Componenti: Chromosome
  • UP000299011 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei23 – 41HelicalSequence analysisAdd BLAST19
Transmembranei95 – 113HelicalSequence analysisAdd BLAST19
Transmembranei119 – 141HelicalSequence analysisAdd BLAST23
Transmembranei153 – 171HelicalSequence analysisAdd BLAST19
Transmembranei183 – 199HelicalSequence analysisAdd BLAST17
Transmembranei220 – 236HelicalSequence analysisAdd BLAST17
Transmembranei242 – 261HelicalSequence analysisAdd BLAST20
Transmembranei268 – 288HelicalSequence analysisAdd BLAST21
Transmembranei300 – 320HelicalSequence analysisAdd BLAST21
Transmembranei332 – 352HelicalSequence analysisAdd BLAST21
Transmembranei405 – 421HelicalSequence analysisAdd BLAST17
Transmembranei433 – 452HelicalSequence analysisAdd BLAST20
Transmembranei458 – 481HelicalSequence analysisAdd BLAST24
Transmembranei488 – 505HelicalSequence analysisAdd BLAST18
Transmembranei511 – 529HelicalSequence analysisAdd BLAST19
Transmembranei550 – 571HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		523841.HFX_1592

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini890 – 993AglB_L1InterPro annotationAdd BLAST104

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1008 – 1047DisorderedSequence analysisAdd BLAST40

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the STT3 family.ARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		arCOG02043, Archaea

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008803_0_0_2

Identification of Orthologs from Complete Genome Data

More...OMAi		SWYHWRT

Database of Orthologous Groups

More...OrthoDBi		5183at2157

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR041154, AglB_P1
IPR003674, Oligo_trans_STT3
IPR026410, OlisacTrfase_arch

The PANTHER Classification System

More...PANTHERi		PTHR13872, PTHR13872, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF18079, AglB_L1, 1 hit
PF02516, STT3, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR04154, archaeo_STT3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

I3R4Y8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSADTERIED SGSKSVLELA KDWYHVPALL VILVGMLTLR LRSYSNFIRG 
        60         70         80         90        100
GEVLFSGNDA WYHLREVTYT VQNWPSTMPF DPWTYFPFGT SVGQFGTIYD 
       110        120        130        140        150
QIIATAALVV GLGSPSPDLV AKTLLVAPAV FGTLVAIPTF LIGRRLGGRT 
       160        170        180        190        200
GGLFGVLILA LLPGTFLRRG LVGFADHNIA EPFFQGFAVV TVMIALTVAN 
       210        220        230        240        250
REKPVWELVA ARDFDALRST LIWSALAGVA MAIYMWSWPP GVLLVGIFGL 
       260        270        280        290        300
FLVLQMVADY VRGRSPEHVA FVGAVSLGVT GLLMFVPLHE MSFSATSFSL 
       310        320        330        340        350
LQPVVSFVIA LGAVFLAALA RFWENNDVDD RGYPVAVGGL AVAGIVLISV 
       360        370        380        390        400
VLPDAFNSIA RNFLRTVGFS AGAATRTIGE AQPFLSSSTL QRTGMTAAER 
       410        420        430        440        450
IMSEYGFTFF TGLVGAIWLV GKPLVSEGDT RKVGYVFGSL AVIGLIFLAP 
       460        470        480        490        500
AIPAGIGGLV GIDSALISLA IVTAIIVGAV LQADYESEHL FVLVWAAIIT 
       510        520        530        540        550
SAAFTQVRFN YYLAVVVAVM NAYLLREILS FDVIGLADVD RLENVSLGTV 
       560        570        580        590        600
AVVAVALLLI LTPVLMVPIQ LGNAGTSSNA LESARSGPGG VTQWQSTFDW 
       610        620        630        640        650
MQNNTPEEGE FGGASNEMEY YGTYKATNDF EYADGTYGVM SWWDYGHWIT 
       660        670        680        690        700
VLGERIPNAN PFQQGAKEAA NFLLAPNETQ ASNVLAEQSE EGNETRYVMV 
       710        720        730        740        750
DWQMASTDSK FGAPTIFYNK QNVSSSDFYS AYYGLQRQDG QERLVSSTTL 
       760        770        780        790        800
KDQRYYESLM VRLYEYHGSA RNPSPIVVDW EERTSRDGST TFKVTPSDNK 
       810        820        830        840        850
PVKSFRTMDA AKAYVANDTT SQIGGLGAFP EERVAALEHY RLVKSSNSTA 
       860        870        880        890        900
LRSQSYYNSI ASAGRTYGIQ PRALLGNNPA WVKTFERVPG ATVEGDGAPA 
       910        920        930        940        950
NATVTARVEM RDPVSGTTFN YTQQAQTDAN GEFTMTLPYS TTGYDDYGPD 
       960        970        980        990       1000
NGYTNVSVRA VDDYTFTGPT SFEGNNTFVT YQATNVSVEE GLVNGAEDGT 
      1010       1020       1030       1040 
VQVSLEQTEQ EITLNESSSD DSSSDDAETN ESTSASIDAG SVPAVAA
Length:1,047
Mass (Da):113,009
Last modified:September 5, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9721E4FE4AEB24FA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP001868 Genomic DNA Translation: AFK19298.1
CP007551 Genomic DNA Translation: AHZ21345.1
AOLO01000002 Genomic DNA Translation: EMA04513.1
CP039139 Genomic DNA Translation: QCQ75765.1

NCBI Reference Sequences

More...RefSeqi		WP_004056863.1, NZ_CP039139.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AFK19298; AFK19298; HFX_1592
AHZ21345; AHZ21345; BM92_01155
EMA04513; EMA04513; C439_02522
QCQ75765; QCQ75765; E6P09_10990

Database of genes from NCBI RefSeq genomes

More...GeneIDi		40156949

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hme:HFX_1592

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|523841.21.peg.509

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001868 Genomic DNA Translation: AFK19298.1
CP007551 Genomic DNA Translation: AHZ21345.1
AOLO01000002 Genomic DNA Translation: EMA04513.1
CP039139 Genomic DNA Translation: QCQ75765.1
RefSeqiWP_004056863.1, NZ_CP039139.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi523841.HFX_1592

Genome annotation databases

EnsemblBacteriaiAFK19298; AFK19298; HFX_1592
AHZ21345; AHZ21345; BM92_01155
EMA04513; EMA04513; C439_02522
QCQ75765; QCQ75765; E6P09_10990
GeneIDi40156949
KEGGihme:HFX_1592
PATRICifig|523841.21.peg.509

Phylogenomic databases

eggNOGiarCOG02043, Archaea
HOGENOMiCLU_008803_0_0_2
OMAiSWYHWRT
OrthoDBi5183at2157

Enzyme and pathway databases

UniPathwayiUPA00378

Family and domain databases

InterProiView protein in InterPro
IPR041154, AglB_P1
IPR003674, Oligo_trans_STT3
IPR026410, OlisacTrfase_arch
PANTHERiPTHR13872, PTHR13872, 1 hit
PfamiView protein in Pfam
PF18079, AglB_L1, 1 hit
PF02516, STT3, 1 hit
TIGRFAMsiTIGR04154, archaeo_STT3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI3R4Y8_HALMT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: I3R4Y8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: May 25, 2022
This is version 53 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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