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UniProtKB - I3PFJ3 (DOD1U_BETVU)
Protein
4,5-DOPA dioxygenase extradiol 1
Gene
DODA1
Organism
Beta vulgaris (Sugar beet)
Status
Functioni
Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.
1 PublicationCatalytic activityi
- EC:1.13.11.29Curated
Cofactori
Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity
: betalain biosynthesis Pathwayi
This protein is involved in the pathway betalain biosynthesis, which is part of Pigment biosynthesis.CuratedView all proteins of this organism that are known to be involved in the pathway betalain biosynthesis and in Pigment biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 22 | ZincBy similarity | 1 | |
Metal bindingi | 60 | ZincBy similarity | 1 | |
Metal bindingi | 182 | ZincBy similarity | 1 | |
Metal bindingi | 236 | ZincBy similarity | 1 |
GO - Molecular functioni
- ferrous iron binding Source: InterPro
- stizolobate synthase activity Source: UniProtKB-EC
- zinc ion binding Source: InterPro
GO - Biological processi
- cellular aromatic compound metabolic process Source: InterPro
Keywordsi
Molecular function | Dioxygenase, Oxidoreductase |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
UniPathwayi | UPA00278 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:DODA11 Publication |
Organismi | Beta vulgaris (Sugar beet)Imported |
Taxonomic identifieri | 161934 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › Caryophyllales › Chenopodiaceae › Betoideae › Beta |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000431981 | 1 – 275 | 4,5-DOPA dioxygenase extradiol 1Add BLAST | 275 |
Expressioni
Inductioni
Regulated by MYB1.1 Publication
Family & Domainsi
Sequence similaritiesi
Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.Curated
Family and domain databases
CDDi | cd07363, 45_DOPA_Dioxygenase, 1 hit |
InterProi | View protein in InterPro IPR014436, Extradiol_dOase_DODA IPR004183, Xdiol_dOase_suB |
Pfami | View protein in Pfam PF02900, LigB, 1 hit |
PIRSFi | PIRSF006157, Doxgns_DODA, 1 hit |
i Sequence
Sequence statusi: Complete.
I3PFJ3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKMMNGEDAT DQMIKESFFI THGNPILTVE DTHPLRPFFE TWREKIFSKK
60 70 80 90 100
PKAILIISGH WETVKPTVNA VHINDTIHDF DDYPAAMYLF KYPAPGAPEL
110 120 130 140 150
ARKVEEILKK SGFETAETDE KRGLDHGAWV PLMLMYPEAD IPVCQLSVQP
160 170 180 190 200
HLDGTYHYNL GRALAPLKND GVLIIGSGSA THPLDETPHY FDGVAPWAAA
210 220 230 240 250
FDSWLRKALI NGRFEEVNIY ETKAPNWKLA HPFPEHFYPL HVVLGAAGEK
260 270
WKAELIHSSW DHGTLCHGSY KFTSA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HQ656021 Genomic DNA Translation: AET43287.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | HQ656021 Genomic DNA Translation: AET43287.1 |
3D structure databases
AlphaFoldDBi | I3PFJ3 |
SMRi | I3PFJ3 |
ModBasei | Search... |
Enzyme and pathway databases
UniPathwayi | UPA00278 |
Family and domain databases
CDDi | cd07363, 45_DOPA_Dioxygenase, 1 hit |
InterProi | View protein in InterPro IPR014436, Extradiol_dOase_DODA IPR004183, Xdiol_dOase_suB |
Pfami | View protein in Pfam PF02900, LigB, 1 hit |
PIRSFi | PIRSF006157, Doxgns_DODA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DOD1U_BETVU | |
Accessioni | I3PFJ3Primary (citable) accession number: I3PFJ3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 4, 2015 |
Last sequence update: | September 5, 2012 | |
Last modified: | May 25, 2022 | |
This is version 23 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families