Fork-head domain-containing protein

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• beta-catenin binding Source: Ensembl
• DNA-binding transcription activator activity, RNA polymerase II-specific Source: Ensembl
• enzyme binding Source: Ensembl
• identical protein binding Source: Ensembl
• sequence-specific double-stranded DNA binding Source: Ensembl
• transcription factor binding Source: Ensembl

GO - Biological processⁱ

• cell cycle arrest Source: Ensembl
• insulin receptor signaling pathway Source: Ensembl
• mitotic G2 DNA damage checkpoint Source: Ensembl
• negative regulation of angiogenesis Source: Ensembl
• negative regulation of cell population proliferation Source: Ensembl
• negative regulation of G0 to G1 transition Source: Ensembl
• negative regulation of smooth muscle cell differentiation Source: Ensembl
• positive regulation of cell cycle arrest Source: Ensembl
• stem cell differentiation Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• beta-catenin binding Source: Ensembl
• enzyme binding Source: Ensembl
• identical protein binding Source: Ensembl
• transcription factor binding Source: Ensembl

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Compositional bias

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MDPGNKNSAT EAAAIIDLDP DFEPQSRPRS CTWPLPRPEP TTKPSEPPEV 
        60         70         80         90        100
EPGLGEKVHT EGHSEPILLP SRLPEPAGGP QPGILGAVTG PRKGGSRRNA 
       110        120        130        140        150
WGNQSYAELI SQAIESAPEK RLTLAQIYEW MVRTVPYFKD KGDSNSSAGW 
       160        170        180        190        200
KNSIRHNLSL HSKFIKVHNE ATGKSSWWML NPEGGKSGKA PRRRAASMDS 
       210        220        230        240        250
SSKLLRGRSK APKKKPSVLP APPEGATPTS PIGHFSKWSG SPCSRNREEA 
       260        270        280        290        300
DMWTAFRPRS SSNASTVSTR LSPMRPESEV LAEEEIPASV SSYAGGVPPT 
       310        320        330        340        350
LNEDLELLDG LNLTSPHSLL SRSSLSGFSL QHPGVPGPLH TYGASLFGPA 
       360        370        380        390        400
EGPMSAEGCF SSSQSLEALL TSDTPPPPAD VLMTQVDPIL SQAPTLLLLG 
       410        420        430        440        450
GMPSSSKLAT GVGLCPKPLE APGPSSLVPT LPMMAPPPVM GGAPIPKALG 
       460        470        480        490        500
TPVLTPPTEA SSQDRMPQDL DLDMYMENLE CDMDNIISDL MDGGEGLDFN 

FEPDP                                                  

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ